Hip Fractures: The St Ann's Bay Regional Hospital Experience.

OBJECTIVES: To study the outcome of hip fractures in a cohort of patients from two different time periods (2002-2003 and 2006-2008). METHODS: Patients treated for hip fractures at the St Ann's Bay Regional Hospital (SABRH), which provides orthopaedic care for the parishes of St Ann, St Mary and Portland, were retrospectively analysed between 2002-2003 and 2006-2008. RESULTS: A significant increase in the recorded incidence of hip fractures, from 19 in the 2002-2003 time period to 101 in the 2006-2008 time period was noted. There was a drastic fall in the in-hospital mortality rate (43% in the 2002-2003 time period compared to 4.5% in the 2006-2008 time period). In the 2006-2008 period, 82.9% of patients were ambulant at discharge compared to 36% from the 2002-2003 time period. CONCLUSION: Early surgical fixation is necessary to allow rapid mobilization in these patients for whom the consequences of bed rest would otherwise be devastating.

Endoscopic carpal tunnel release in Jamaica--seven years experience.

OBJECTIVE: To assess the patient profile and outcome of treatment, by endoscopic release, of patients with carpal tunnel syndrome. METHODS: A descriptive study was done using data from two sets of patients who had endoscopic carpal tunnel release in Jamaica from 2004 to 2006 and 2006 to 2010. The medical records of patients who had a diagnosis of carpal tunnel syndrome using symptoms, clinical signs and confirmation by nerve conduction test were reviewed. The data were analysed using SPSS and Micosoft Excel. RESULTS: A total of 68 patients with 75 cases of carpal tunnel syndrome were done. Fifty-two (76%) of these patients were females and about 50% were older than 41 years old. There were 61 (90%) unilateral cases. Of these, the majority of cases affected the right hand. All patients had improvement in symptoms after one week, required minimal analgesic use, had good compliance with rehabilitation and returned to work after about two weeks. There were three cases of pilar tenderness, two cases of transient paraesthesia in the index finger which resolved after three weeks. There were three failed cases from the first series which had to be converted to open carpal tunnel release. The complication rate was 6.7%. No serious complications occurred in the second series and all were treated successfully without interventional surgery. The rate of conversion to open release was 4%. CONCLUSION: Carpal tunnel affects mostly middle aged females and when treatment is done by endoscopic release, there is a fast resolution of symptoms and early return to work.

Endoscopic carpal tunnel release in jamaica: seven years experience / Liberación endoscópica del túnel carpiano en jamaica: siete anos de experiencia

OBJECTIVE: To assess the patient profile and outcome of treatment, by endoscopic release, of patients with carpal tunnel syndrome. METHODS: A descriptive study was done using data from two sets ofpatients who had endoscopic carpal tunnel release in Jamaica from 2004 to 2006 and 2006 to 2010. The medical records of patients who had a diagnosis of carpal tunnel syndrome using symptoms, clinical signs and confirmation by nerve conduction test were reviewed. The data were analysed using SPSS and Micosoft Excel®. RESULTS: A total of 68 patients with 75 cases of carpal tunnel syndrome were done. Fifty-two (76%) of these patients were females and about 50% were older than 41 years old. There were 61 (90%) unilateral cases. Of these, the majority of cases affected the right hand. All patients had improvement in symptoms after one week, required minimal analgesic use, had good compliance with rehabilitation and returned to work after about two weeks. There were three cases of pilar tenderness, two cases of transient paraesthesia in the index finger which resolved after three weeks. There were three failed cases from the first series which had to be converted to open carpal tunnel release. The complication rate was 6.7%. No serious complications occurred in the second series and all were treated successfully without interventional surgery. The rate ofconversion to open release was 4%. CONCLUSION: Carpal tunnel affects mostly middle aged females and when treatment is done by endoscopic release, there is a fast resolution of symptoms and early return to work.

OBJETIVO: Evaluar el perfil del paciente y el resultado clínico del tratamiento de pacientes con el síndrome del túnel carpiano tratados mediante liberación endoscópica. MÉTODOS: Se llevó a cabo un estudio descriptivo, usando datos de dos conjuntos de pacientes a quienes se les realizó una liberación endoscópica del túnel carpiano en Jamaica entre 2004 y 2006; 2006 y 2010. Se revisaron las historias clínicas de pacientes con un diagnóstico de síndrome del túnel carpiano, usando síntomas, senales clínicas y confirmación mediante la prueba de conducción de nervio. Los datos fueron analizados usando SPSS y Micosoft Excel®. RESULTADOS: Se analizó un total de 68 pacientes con 75 casos de síndrome del túnel carpiano. Cincuenta y dos (76%) de estas pacientes fueron mujeres, y aproximadamente 50% tenían más de 41 anos de edad. Hubo 61 (90%) casos unilaterales. De éstos, la mayoría de casos tuvo afectación de la mano derecha. Todos los pacientes experimentaron una mejoría en los síntomas después de una semana; necesitaron un uso mínimo de analgésicos, cumplieron bien con la rehabilitación, y regresaron al trabajo luego de dos semanas aproximadamente. Hubo tres casos de sensibilidad del talón de la mano, y dos casos deparestesia transitoria del dedo índice, que se resolvieron después de tres semanas. Hubo tres casos fallidos que tuvieron que ser convertidos en liberación abierta del túnel carpiano. La tasa de complicación fue 6.7%. No ocurrió ninguna complicación seria en esta serie, y todas fueron tratadas exitosamente sin intervención quirúrgica. La tasa de conversión para abrir la liberación fue 4%. CONCLUSIÓN: El túnel carpiano afecta principalmente a las mujeres de mediana edad, y cuando el tratamiento se realiza mediante liberación endoscópica, se produce una resolución rápida de los síntomas y un temprano regreso al trabajo.

The Haitian earthquake crisis: the first responders' perspective.

A catastrophic earthquake of the magnitude of 7 on the Richter scale hit Haiti's capital Port-au-Prince on Tuesday January 12, 2010 at a focal depth of 13 km or 8.1 miles. Four days after, a joint Ministry of Health (Jamaica)/Jamaica Medical Doctor Association (JMDA) initiated CARICOM (Caribbean Community) endeavour entered Haiti to establish a system whereby medical help could be offered to the Haitian populace. Two hospital sites were established (one for life-saving surgeries, the other for limb reconstructions), clinic facilities for walk-in wounded and other related cases, and mobile clinic services (called the Train of Hope). Within 48 hours, a total of 43 operations were performed (26 major 17 minor). Within eight days, a total of 1229-1249 patients were seen in all the facilities established. This included a total of 106 operations (64 major 42 minor). There were a total of 21 life-saving amputations.

Outcomes of long bone fractures treated by open intramedullary nailing at the St Ann's bay hospital, Jamaica / Resultados clínicos de las fracturas de huesos largos tratadas mediante enclavijado intramedular abierto en el hospital de Saint Ann's bay, Jamaica

Between May 2001 to August 2004, 35 patients had open nailing of long bones. There were 40 fractures fixed. Of these 40 fractures, there were 25 femoral fractures, 11 were tibial fractures and 4 were humeral fractures. There were 33 (82.5%) closed fractures and 7 (17.5%) open fractures. In the group of patients with open fractures, there were two Grade I, two Grade II and three Grade IIIB. Seven (20%) patients were lost to follow-up; all of whom had closed fractures. The final analysis as it relates to complications was done using 28 patients with 32 fractures. The majority of fractures healed without significant complication. All the patients with closed fractures went on to bony union. There was one non-union and three delayed unions. There were two infections (osteomyelitis) and this was from the open fracture cohort. This represents an infection rate of 28.6% in this cohort. Two (7.0%) patients had persistent pain and one (3.6%) patient had early removal of the nail because of failure of fixation. The mean time from injury to surgery for the fractured femur was 15.5 (range 0-49) days; fractured tibia 24.4 (range 0-40), days and fractured humerus 41.5 (20-81) days. The mean hospital stay was 18.9 (range 9-37) days for patients with fractured femur; for fractured tibia, it was 20.5 (range 3-82) days and for fractured humerus, it was 22.7 (range 3-82) days. The mean postoperative stay was 4.1 (range 1-14) days for fractured femur, 4.5 (range 1-14) days for fractured tibia and 4.0 (range 1-10) days for fractured humerus. The mean time to healing (consolidation) as defined by X-rays was 5.0 (range 3-11) months for fractured femur, 5.2 ( range 3-11) months for tibia and 7.0 (range 6- 8) months for fractured humerus.

Desde mayo de 2001 hasta agosto de 2004, 35 pacientes recibieron reducción de fracturas de huesos largos mediante enclavijado a cielo abierto. Se produjeron 40 fijaciones de fracturas. De estas 40 fracturas, 25 fracturas fueron del fémur, 11 fueron de la tibia, y 4 del húmero. Hubo 33 (82.5%) fracturas cerradas y 7 (17.5%) fracturas abiertas. En el grupo de pacientes con fracturas abiertas, hubo dos fracturas de grado I, dos de grado II y tres de grado IIIB. El análisis final en cuanto a las complicaciones, se realizó con 28 pacientes con 32 fracturas. La mayoría de las fracturas se curaron sin complicaciones significativas. Todos los pacientes con fracturas cerradas lograron finalmente la unión ósea. Hubo uno que no logró la unión y tres uniones retardadas. Se produjeron dos infecciones (osteomielitis), provenientes de la cohorte de fractura abierta. Esto representa una tasa de infección del 28.6% en dicha cohorte. Dos (7.0%) pacientes presentaban dolores persistentes, y a un (3.6%) paciente le fue retirado el clavo tempranamente debido a que la fijación falló. El tiempo promedio desde la lesión hasta la cirugía, fue de 15.5 días (rango 0-49) para la fractura del fémur; 24.4 días (rango 0-40) para la fractura de la tibia, y 41.5 días (20-81) para la fractura del húmero. La estancia promedio en el hospital fue de 18.9 días (rango 9-37) para los pacientes con el fémur fracturado; para la fractura de la tibia fue de 20.5 días (rango 3-82), y para el húmero fracturado fue 22.7 días (rango 3-82). La estadía postoperatoria promedio fue 4.1 días (rango 1-14) para el fémur fracturado, 4.5 días (rango 1-14) para la tibia fracturada, y 4.0 días (rango 1-10) días para los casos de fractura del húmero. El tiempo promedio de sanación (consolidación) tal como lo definieron los rayos X fue 5.0 meses (rango 3-11) para el fémur fracturado, 5.2 meses (rango 3-11) para la tibia y 7.0 meses (rango 6-8) para el húmero fracturado.

Outcomes of long bone fractures treated by open intramedullary nailing at the St. Ann's Bay Hospital, Jamaica.

Between May 2001 to August 2004, 35 patients had open nailing of long bones. There were 40 fractures fixed. Of these 40 fractures, there were 25 femoral fractures, 11 were tibial fractures and 4 were humeral fractures. There were 33 (82.5%) closed fractures and 7 (17.5%) open fractures. In the group of patients with open fractures, there were two Grade I, two Grade II and three Grade IIIB. Seven (20%) patients were lost to follow-up; all of whom had closed fractures. The final analysis as it relates to complications was done using 28 patients with 32 fractures. The majority of fractures healed without significant complication. All the patients with closed fractures went on to bony union. There was one non-union and three delayed unions. There were two infections (osteomyelitis) and this was from the open fracture cohort. This represents an infection rate of 28.6% in this cohort. Two (7.0%) patients had persistent pain and one (3.6%) patient had early removal of the nail because of failure of fixation. The mean time from injury to surgery for the fractured femur was 15.5 (range 0-49) days; fractured tibia 24.4 (range 0-40), days and fractured humerus 41.5 (20-81) days. The mean hospital stay was 18.9 (range 9-37) days for patients with fractured femur; for fractured tibia, it was 20.5 (range 3-82) days and for fractured humerus, it was 22.7 (range 3-82) days. The mean postoperative stay was 4.1 (range 1-14) days for fractured femur, 4.5 (range 1-14) days for fractured tibia and 4.0 (range 1-10) days for fractured humerus. The mean time to healing (consolidation) as defined by X-rays was 5.0 (range 3-11) months for fractured femur 5.2 (range 3-11) months for tibia and 7.0 (range 6-8) months for fractured humerus.

Leiomiosarcoma primario de region retroauricular derecha: presentación de un caso / Primary leiomyosarcoma of region straight (retroauricular):presentation of a case

Se presenta un caso de Leiomiosarcoma de región retroauricular derecha de una joven de 27 años de edad. Diagnosticado 07/09/82 a los 17 años de la resección quirúrgica, no hay signos de recuperación local, ni metastasica. Se destaca la rareza de la localización de este tumor, así como los aspectos clínicos y terapeúticos más caracteristicos. Se realiza una revisión biblográfica relacionada con el tema.(AU)

Medical readiness training exercise in El Salvador, Central America, 1996.

Medical Readiness Training Exercises (MEDRETEs) can be a valuable training tool for U.S. Army personnel in remote areas of deployment. We report our experience of the MEDRETE in El Salvador in 1996. Working with foreign physicians of the host country was a positive experience in which we learned local customs and mutual cooperation. Evaluation and treatment of nearly 6,000 patients increased goodwill in the community and provided an opportunity for teamwork for Army Reserve medical units, including increased discussions of public health issues. We also report on the field applicability of the advanced laboratory and pharmacy equipment we included in our training.

A chromosome 9 deletion in Plasmodium falciparum results in loss of cytoadherence.

Many lines of Plasmodium falciparum undergo a deletion of the right end of chromosome 9 during in vitro culture accompanied by loss of cytoadherence and gametocytogenesis. Selection of cytoadherent cells from a mixed population co-selects for those with an undeleted chromosome 9 and the selected cells produce gametocytes. The deletion also results in loss of expression of PfEMP1, the putative cytoadherence ligand, suggesting that PfEMP1 or a regulatory gene controlling PfEMP1 expression and gametocytogenesis may be encoded in this region. We have isolated several markers for the deleted region and are currently using a YAC-P. falciparum library to investigate this region of the genome in detail.

A chromosome 9 deletion in Plasmodium falciparum results in loss of cytoadherence

Many lines of Plasmodium falciparum undrgo a deletion of the right end of chromosome 9 during in vitro culture accompanied by loss of cytoadherence and gametocytogenesis. Selection of cytoadherent cells from a mixed population co-selects for those with an undeleted chromosome 9 and selected cells produce gametocytes. The deletion also results in loss of expression of PfEMP1, the putative cytoadherence ligand, suggesting PfEMP1 or a regulatory gene controlling PfEMP1 expression and gametocytogenesis may be encoded in this region. We have isolated several markers for the deleted region and are currently using a YAC-P. falciparum library to investigate this region of the genome in detail

Women's physical activity and pregnancy outcome: a longitudinal analysis from the Philippines.

We assessed the effects of physical activity on pregnancy outcome in 2741 Filipino women identified during pregnancy as part of a two-year longitudinal study. Specific elements of physical activity hypothesized to be relevant to pregnancy outcome were posture, energy expenditure, and physical stress. Variables were developed for nine household and 48 formal and informal economic activities. Analyses were stratified by whether the woman performed formal waged work outside of the home, income-related activity at home, or was economically inactive. Results show that traditional definitions of physical activity and work based on participation in the formal labour force ignore a sizeable amount of home economic production, as well as the physical demands of housework. We saw no difference in risk of low birthweight or preterm delivery in economically active compared to economically inactive women. However, we found that increased amounts of standing activity affected pregnancy outcome in certain groups of women. Accurate assessment of the effects of physical activity during pregnancy must examine specific components of the activity, rather than relying on formal employment as a proxy for exposure.

PIP: The authors assessed the effects of physical activity on pregnancy outcome in 2741 Filipino women identified during pregnancy as part of a 2-year longitudinal study. Specific elements of physical activity hypothesized to be relevant to pregnancy outcome were posture, energy expenditure, and physical stress. Variables were developed for 9 household and 48 formal and informal economic activities. Analyses were stratified by whether the women performed formal waged work outside the home, income-related activity at home, or were economically inactive. Results show that traditional definitions of physical activity and work based on participation in the formal labor force ignore a sizeable amount of home economic production, as well as the physical demands of housework. The authors saw no difference in risk of low birthweight or preterm delivery in economically active compared to economically inactive women. However, they did find that increased amounts of standing activity affected pregnancy outcome in certain groups of women. Accurate assessment of the effects of physical activity during pregnancy must examine specific components of the activity, rather than relying on formal employment as a proxy for exposure.

Relationship between muscle potassium and body potassium in infants with malnutrition

Specimens of muscle were obtained with a biopsy needle from 23 Jamaican children who were recovering from malnutrition. The samples were analysed for water, fat, nitrogen, and potassium, total body potassium was also measured. Muscle water is increased, but potassium concentration declines in malnutrition. A significant relationship exists between the depletions of muscle potassium and of total body potassium in malnourished infants. Analysis of muscle biopsy samples may lead to a better understanding of the response of tissue to protein depletion at the cellular level (Summary)