RESUMEN
The genus Elsinoe includes many aggressive plant pathogens that infect various economically important agricultural, horticultural and forestry plants. Significant diseases include citrus scab caused by E. fawcettii and E. australis, grapevine spot anthracnose by E. ampelina, and the emerging Eucalyptus scab and shoot malformation disease caused by the recently described E. necatrix. Despite their importance as plant pathogens, little is known regarding the biology of many Elsinoe spp. To gain insights into the reproductive biology of these fungi, we characterized the mating-type loci of seven species using whole genome sequence data. Results showed that the MAT1 locus organization and its flanking genes is relatively conserved in most cases. All seven species manifested a typical heterothallic mating system characterized by having either the MAT1-1 or MAT1-2 idiomorph present in an isolate. These idiomorphs were defined by the MAT1-1-1 or the MAT1-2-1 gene, respectively. A unique MAT1-1 idiomorph containing a truncated MAT1-2-1 gene, and a MAT1-1-1 gene, was identified in E. necatrix and E. fawcettii genomes. Additionally, two idiomorph-specific proteins were found in the MAT1-1 and MAT1-2 idiomorphs of E. australis. Universal mating-type markers confirmed heterothallism across 21 Elsinoe spp., are poised to advance future studies regarding the biology of these fungi.
Asunto(s)
Ascomicetos , Genes del Tipo Sexual de los Hongos , Ascomicetos/genética , Reproducción/genéticaRESUMEN
Los déficits en salud tras la excarcelación son habituales, incluso con mayor riesgo de muerte. En estos casos, la principal causa de muerte es el uso de heroína y de otros opioides, pero hay otras posibles causas, muchas de ellas potencialmente prevenibles. Los grupos más vulnerables al incremento de la morbimortalidad tras la excarcelación son los consumidores de drogas, los enfermos mentales y los internos extranjeros que proceden de países con pocos recursos económicos. Es urgente implementar intervenciones que optimicen el acceso a los dispositivos sanitarios después de la excarcelación, eviten interrupciones de la continuidad de la atención y del tratamiento prescrito en prisión, y reduzcan la morbimortalidad. Para ello, se precisa coordinar de forma efectiva la atención dentro y fuera de la prisión y aplicar medidas de apoyo. En este trabajo, se presenta el proyecto implementado en las prisiones de Cataluña, que ha utilizado el "enfermero de enlace" (EE) como figura clave del proceso, y el procedimiento interno y externo utilizado para facilitar el adecuado traspaso de información sanitaria y terapéutica, vincular a los pacientes excarcelados a los dispositivos sanitarios y asegurarse de que estos los reciben en el tiempo y la forma adecuados
Deficits in health after being released are common, and even include a higher risk of death. In these cases, the main cause of death is the use of heroin and other opioids, but there are other causes and most of them are potentially preventable. The most vulnerable groups to the increase in post-release morbidity and mortality are drug users, the mentally ill and foreign inmates from countries with fewer economic resources. What is urgently needed is to implement interventions that optimize access to health devices after prison release, avoid interruptions in the continuity of care and treatment prescribed in prison and reduce morbidity and mortality. To achieve this, it is necessary to coordinate effective forms of care inside and outside prison and apply support measures. We present the project implemented in prisons in Catalonia, where the "liaison nurse" was used as a key figure in the process. We also present the internal and external procedure used to facilitate the transfer of sanitary and therapeutic information, to link released patients to health devices and to ensure that they are received in a timely and appropriate manner