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1.
Turk Neurosurg ; 27(2): 245-251, 2017.
Artículo en Inglés | MEDLINE | ID: mdl-27593786

RESUMEN

AIM: The aim of the study was to develop new equipment for the assessment of the flexibility of the spine with different forces. This new system should provide a different perspective to adolescent idiopathic scoliosis (AIS) for the selection of fusion levels and surgical success. MATERIAL AND METHODS: Eighteen patients suffering from AIS who were scheduled to undergo posterior instrumented spinal fusion in our clinic were recruited in this study. The Electronic Traction Table (ETT) that was designed in our clinic was used to evaluate the radiogical and clinical parameters of the spine. RESULTS: The significant prescriptive angle of major Cobb angles between postoperative angles were longitudinal traction and lateral pushing Cobb angles. Longitudinal traction and lateral pushing angles were more correlated with correction ratios. There was a significant difference between longitudinal traction minor Cobb angle, longitudinal traction lateral pushing minor Cobb angle and postoperative minor Cobb angles. CONCLUSION: The deformity is needed to balance both tractional and rotational forces and useful technique to evaluate curve flexibility before the operation. Electronic traction table is a new device for determining preoperative flexibility with longitudinal traction and lateral pushing radiographs. It can be useful for choosing selective fusion levels at the proximal and distal end of the vertebral column.


Asunto(s)
Diagnóstico por Computador/métodos , Radiografía/métodos , Escoliosis/diagnóstico , Adolescente , Femenino , Humanos , Masculino , Escoliosis/diagnóstico por imagen , Escoliosis/cirugía , Fusión Vertebral
2.
Acta Orthop Traumatol Turc ; 50(1): 37-41, 2016.
Artículo en Inglés | MEDLINE | ID: mdl-26854047

RESUMEN

OBJECTIVE: Compartment syndrome is one of the most devastating complications in orthopedics both for the patient and the treating physician. Among the many causes, trauma and its treatment are the most common reasons for compartment syndrome, which most frequently occurs in the lower leg following tibial fractures. Since bridge plating of difficult metadiaphyseal tibial fractures is becoming increasingly popular, serious concerns have been raised about the increased intracompartmental pressures and possible compartment syndrome. METHODS: This study investigated the intracompartmental pressure changes in anterolateral compartment of the leg during and immediately after anterolateral bridge plating of tibial fractures. Intracompartmental pressures were measured before and during plate application, just after the completion of fixation, and immediately and 4-5 min after the tourniquet release in 22 isolated closed comminuted tibial fractures. RESULTS: Baseline anterolateral compartment pressures were higher than those on the uninjured side (9.3 vs 27.8 mmHg). Pressures were 69.5, 57.4, 65.8, and 56.8 mmHg, respectively, for the other measurements times. None of the patients received prophylactic fasciotomy, and none developed clinical compartment syndrome. CONCLUSION: We found that anterolateral compartmental pressures were higher than pressures on the uninjured side in all patients. Although there is a considerable increase in intracompartmental pressures during and immediately after anterolateral percutaneous bridge plating of comminuted tibial fractures, intraoperative prophylactic fasciotomy is not routinely needed. One should monitor the patients on the first postoperative day for signs of compartment syndrome. Fasciotomy decisions should be based on both clinical symptoms and serial intracompartmental pressure measurements rather than a single measurement.


Asunto(s)
Placas Óseas/efectos adversos , Síndromes Compartimentales , Fijación Interna de Fracturas , Fracturas de la Tibia , Adulto , Fenómenos Biomecánicos , Síndromes Compartimentales/diagnóstico , Síndromes Compartimentales/etiología , Síndromes Compartimentales/fisiopatología , Síndromes Compartimentales/prevención & control , Diagnóstico Precoz , Femenino , Fijación Interna de Fracturas/efectos adversos , Fijación Interna de Fracturas/instrumentación , Fijación Interna de Fracturas/métodos , Humanos , Masculino , Persona de Mediana Edad , Evaluación de Procesos y Resultados en Atención de Salud , Estudios Prospectivos , Fracturas de la Tibia/diagnóstico , Fracturas de la Tibia/cirugía , Tiempo de Tratamiento , Turquía
3.
J Orthop Sci ; 17(6): 705-9, 2012 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-22936208

RESUMEN

AIM: The aim of this prospective study was to evaluate the outcome of open reduction and Tönnis acetabuloplasty as the first method of treating developmental dysplasia of the hip (DDH) in children in early childhood at walking age. MATERIALS AND METHODS: Between 2005 and 2009, 34 hips of 34 children were operated on with the aforementioned method. Mean age was 25.6 (range 12-44) months, and mean follow-up was 3.6 years. During the follow-up period ,the hips were evaluated using the acetabular index and for development of avascular necrosis and redislocation. Functional evaluation was also conducted. RESULTS: Clinically, 97.3 % of patients had excellent and good results. The acetabular angle decreased from 45° preoperatively to 21° early postoperatively and at the last follow-up had improved to 18°. In two hips, type 2 avascular necrosis developed. Hip instability was not observed, and no additional surgery was performed. CONCLUSION: Tönnis acetabuloplasty is a powerful tool to increase primary stability of the hip when acetabular coverage is inadequate in DDH. Besides its acute correction ability, when performed properly, it has no unwanted effects on acetabular growth. As an isolated procedure or as a part of combined open reduction and/or femoral osteotomy, Tönnis type acetabuloplasty is a safe and effective method.


Asunto(s)
Acetábulo/cirugía , Artroplastia/métodos , Enfermedades del Desarrollo Óseo/cirugía , Articulación de la Cadera , Deformidades Adquiridas de la Articulación/cirugía , Osteotomía/métodos , Factores de Edad , Enfermedades del Desarrollo Óseo/diagnóstico , Enfermedades del Desarrollo Óseo/etiología , Preescolar , Femenino , Fémur/cirugía , Estudios de Seguimiento , Humanos , Lactante , Deformidades Adquiridas de la Articulación/diagnóstico , Deformidades Adquiridas de la Articulación/etiología , Masculino , Estudios Prospectivos , Rango del Movimiento Articular , Resultado del Tratamiento
4.
Eklem Hastalik Cerrahisi ; 22(2): 85-8, 2011 Aug.
Artículo en Turco | MEDLINE | ID: mdl-21762063

RESUMEN

OBJECTIVES: This study investigated whether the confusion about the acceptable angulation value in fifth metacarpal neck fractures results from the hand radiographs taken at non-standard oblique position. MATERIALS AND METHODS: In this experimental study two Kirshner wires representing the intramedullary axis of the two fracture fragments were placed on a platform prearranged with an angle of 50 degrees between them. The radiographs of the wires were taken on the platform (horizontal) at angles of 0, 30, 45 and 60 degrees. The radiographs were taken without changing the cassette location and the position of the radiography device. RESULTS: The known volar angulation (50 degrees) was measured on the radiographs as 50, 36, 30 and 23 degrees, respectively. CONCLUSION: The main debate about the fifth metacarpal neck fracture is over the acceptable distal fragment volar angulation degree. This degree of angulation is between 30 and 70 degrees in the studies. The presence of such different and inaccurate results in the literature results from the use of non-standard oblique hand radiographs. Standardized radiographs are required in fifth metacarpal neck fractures.


Asunto(s)
Traumatismos de los Dedos/cirugía , Huesos del Metacarpo/lesiones , Fenómenos Biomecánicos , Traumatismos de los Dedos/diagnóstico por imagen , Fracturas Óseas/diagnóstico por imagen , Fracturas Óseas/cirugía , Humanos , Huesos del Metacarpo/diagnóstico por imagen , Huesos del Metacarpo/cirugía , Radiografía , Reproducibilidad de los Resultados
5.
Knee Surg Sports Traumatol Arthrosc ; 18(4): 540-2, 2010 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-19779895

RESUMEN

We describe a case of a previously healthy 35-year-old man who presents with meniscal symptoms, and present the arthroscopic findings of a complicated tear of black lateral meniscus. Investigations revealed that he had underlying alkaptonuria, which was previously undiagnosed without any other findings. After the surgical treatment, the patient's complaints were alleviated and almost no complaints were registered, during the next follow-up.


Asunto(s)
Ocronosis/complicaciones , Lesiones de Menisco Tibial , Adulto , Alcaptonuria/complicaciones , Artroscopía , Estudios de Seguimiento , Humanos , Masculino , Meniscos Tibiales/patología , Ocronosis/patología , Estudios Prospectivos , Resultado del Tratamiento
6.
J Orthop Trauma ; 23(9): 640-4, 2009 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-19897985

RESUMEN

OBJECTIVE: To evaluate knee function in patients having femoral diaphyseal fractures treated with antegrade or retrograde intramedullary nail insertion. DESIGN: Prospective. SETTING: Level I referral center. PATIENTS AND METHODS: Seventy patients having 71 OTA 32 fractures were randomly allocated into 2 groups to be treated with either antegrade or retrograde intramedullary nails inserted with reaming. INTERVENTION: Antegrade nail in 41 fractures and retrograde femoral intramedullary nails in 30 fractures. MAIN OUTCOME MEASURES: Postoperative knee range of motion, Lysholm Knee Score, and isokinetic knee muscle function testing at least 6 months after documented fracture healing, minimum 1 year postoperatively. RESULTS: Groups had similar data with regard to demographics and injury patterns. Mean follow-up time was 44 (range: 25-80) months. Mean knee flexion angle was 132 and 134 degrees, and mean Lysholm Score was 84 and 83.1 in antegrade and retrograde groups, respectively (P = 0.893 and P = 0.701). Isokinetic evaluation revealed similar results for peak torque deficiencies at 30 and 180 degrees per second and total work deficiencies at 180 degrees per second (P > 0.05). Age affected the knee functioning as the higher the age of the patient is, the lower the Lysholm Score and knee flexion angle (r = -0.449, P = 0.0321 and r = -0.568, P = 0.001, respectively). CONCLUSIONS: Knee function seems to have similar clinical results after either antegrade or retrograde nail insertion for femoral diaphyseal fractures when knee range of motion, Lysholm Scores, and isokinetic knee evaluation are considered as outcome measures. With increasing patient age, a decrease in knee functioning should be anticipated in patients with femoral fractures treated with intramedullary nails regardless of technique.


Asunto(s)
Clavos Ortopédicos , Fracturas del Fémur/cirugía , Fijación Intramedular de Fracturas/métodos , Articulación de la Rodilla/cirugía , Accidentes de Tránsito , Adolescente , Adulto , Anciano , Femenino , Fracturas del Fémur/fisiopatología , Fijación Intramedular de Fracturas/instrumentación , Fijación Intramedular de Fracturas/rehabilitación , Humanos , Contracción Isométrica , Articulación de la Rodilla/fisiopatología , Masculino , Persona de Mediana Edad , Estudios Prospectivos , Rango del Movimiento Articular , Recuperación de la Función , Adulto Joven
7.
Acta Orthop Traumatol Turc ; 43(4): 324-30, 2009.
Artículo en Turco | MEDLINE | ID: mdl-19809229

RESUMEN

OBJECTIVES: Optimal surgical fixation method for displaced distal clavicle fractures should not impose limitations on neighboring joint movements. We evaluated the results of surgical treatment of displaced distal clavicle fractures using locked distal radius plates. METHODS: Displaced distal clavicle fractures of 14 consecutive patients (11 men, 3 women; mean age 30 + or - 9 years; range 19 to 51 years) were treated using open reduction and locked distal radius plates. Before final fixation, one patient underwent K-wire fixation with tension band at another center, resulting in nonunion. Except for two cases with late presentation, the mean time to surgery was 5.3 days (range 1 to 17 days). According to the Neer classification, fresh fractures were type II in 10 patients and type III in three patients. Shoulder examinations and functional evaluations were made at 3, 6, and 12 months postoperatively. Functional assessment included the Modified Shoulder Rating Scale and Constant score. RESULTS: All patients achieved full range of motion of the shoulder at six weeks postoperatively. The mean modified shoulder score was 18.7 + or - 1.5 and the mean Constant score was 95.4 + or - 3.0 at 12 months. None of the patients developed implant failure, loss of reduction, skin breakdown, or infection. CONCLUSION: In selected acute fractures and nonunions of the distal clavicle, excellent clinical results are easily achievable with locked distal radius plate fixation because it allows early shoulder movements without necessitating implant removal.


Asunto(s)
Clavícula/lesiones , Clavícula/cirugía , Fijadores Internos , Luxaciones Articulares/cirugía , Adulto , Hilos Ortopédicos , Diseño de Equipo , Femenino , Humanos , Masculino , Persona de Mediana Edad , Músculo Esquelético/fisiología , Músculo Esquelético/fisiopatología , Dolor Postoperatorio/clasificación , Dolor Postoperatorio/epidemiología , Radio (Anatomía)/cirugía , Rango del Movimiento Articular , Adulto Joven
10.
Strategies Trauma Limb Reconstr ; 4(1): 35-9, 2009 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-19340521

RESUMEN

Triceps tendon ruptures are rare injuries. Coexistence of ipsilateral ulnar collateral ligament injury is even rarer. Here, we describe an unusual combination injury to elbow of a 39-year-old male construction worker consisting of triceps tendon rupture, avulsion of elbow ulnar collateral ligament and flexor pronator muscle origin ipsilaterally. A simultaneous repair and reconstruction of all damaged structures was proposed with individualized postoperative rehabilitation. Return to pre-injury level of activities obtained with this treatment protocol. High degree of suspicion and careful examination were needed to prevent missed diagnosis and prolonged instability which may be inevitable after inappropriate treatment of such injury.

13.
J Orthop Sci ; 13(4): 341-7, 2008 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-18696193

RESUMEN

BACKGROUND: Severe disability originating from feet generally requires surgery. In addition to a number of other techniques, triple arthrodesis is still used to treat deformity and instability unresponsive to conservative measures. The aim of this study was to evaluate the results of the triple arthrodesis operation in two groups of patients with different primary etiologies and to identify the possible factors affecting the results. METHODS: During a 4-year period, triple arthrodesis was performed on 25 feet in 20 patients (average age 24.9 years). These patients were divided into two groups according to the primary etiology of the disability: neurogenic and nonneurogenic. Patients were evaluated with pre-and postoperative clinical examinations, American Orthopedic Foot and Ankle Society (AOFAS) Hindfoot and Ankle Scale, radiography, pedobarography, and a general health questionnaire (Short Form 36, SF-36). The need for orthotics and the effect of previous treatments on the end results were also evaluated. RESULTS: The preoperative average AOFAS score improved from 24 to 71 postoperatively. Preoperative AOFAS values of neurogenic cases were significantly lower than those of nonneurogenic cases. Postoperative AOFAS values were found to be lower in neurogenic cases (64.0 vs. 77.6). Marked improvement was observed for all angular measurements. No relation was found between the AOFAS, changes in angular measurements, and pre-and postoperative plantar pressure analysis results. SF-36 results improved postoperatively in both groups. Triple arthrodesis decreased the use of orthotics postoperatively in both groups. Previous treatments were not found to affect the end results in this series. CONCLUSIONS: Triple arthrodesis operation is a surgical option with limited alternatives in patients with disabilities originating from feet. Both neurogenic and nonneurogenic patient groups improved significantly, and we were unable to show any significant differences in the results of these two groups.


Asunto(s)
Artrodesis/métodos , Deformidades del Pie/cirugía , Adolescente , Adulto , Artropatía Neurógena/complicaciones , Niño , Femenino , Estudios de Seguimiento , Deformidades del Pie/etiología , Humanos , Masculino , Persona de Mediana Edad , Resultado del Tratamiento , Adulto Joven
14.
Acta Orthop Traumatol Turc ; 42(1): 59-63, 2008.
Artículo en Turco | MEDLINE | ID: mdl-18354279

RESUMEN

OBJECTIVES: This study was designed to investigate the frequency of requests for computed tomography (CT) examination of the spinal column and pelvis in our emergency orthopedic department, the reasons of requests, and the rates of positive and negative CT examinations. METHODS: We retrospectively reviewed patients for whom a request for CT examination was made by the emergency orthopedic department within a year (September 2005- 2006). The reasons for CT requests, findings in CT reports, and age and sex of the patients were recorded. Findings unrelated and related to the original request denoted a negative and positive CT examination, respectively. RESULTS: Of 24,378 admissions to our emergency orthopedic department, a CT scan was requested in 1,295 patients (5.3%). In 817 patients (63.1%), CT examination involved the pelvis or the spinal column. Of these, 418 CT scans (51.2%) yielded a negative result. The mean age of the patients with a negative CT scan was significantly lower than those having a positive CT scan (40.7 vs 45.1 years; p=0.001). There was no significant difference with respect to sex between patients having negative and positive CT findings (p=0.670). Compared to pelvis CT scans, the frequency of negative CTs was significantly higher for spinal column examinations (p<0.001). The incidence of negative CT scans for upper thoracic and cervical vertebrae was significantly higher than that found for lower thoracic and lumbar regions (p<0.001). CONCLUSION: The high incidence of negative CT scans documented for pelvic and spinal column examinations underlines the need for measures to avoid superfluous CT requests in emergency departments.


Asunto(s)
Tratamiento de Urgencia/estadística & datos numéricos , Evaluación de Resultado en la Atención de Salud , Pelvis/diagnóstico por imagen , Traumatismos Vertebrales/diagnóstico por imagen , Traumatismos Vertebrales/epidemiología , Tomografía Computarizada por Rayos X/estadística & datos numéricos , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Niño , Femenino , Humanos , Masculino , Registros Médicos , Persona de Mediana Edad , Procedimientos Ortopédicos/estadística & datos numéricos , Pelvis/lesiones , Estudios Retrospectivos , Traumatismos Vertebrales/etiología , Turquía/epidemiología , Procedimientos Innecesarios/estadística & datos numéricos
16.
J Orthop Sci ; 12(5): 415-23, 2007 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-17909925

RESUMEN

BACKGROUND: Secondary malignancies arising from benign bone tumors are rare. Their recognition and diagnosis are difficult, and their slow growth and late recurrence require long-term follow-up. In this study, malignant transformation rates of various histological types of benign cartilage-forming bone tumors in large series were evaluated. METHODS: Between 1986 and 2004, a retrospective analysis of 627 cartilage-forming benign bone tumors revealed that 32 patients had malignant transformation. Of the 32 patients, 14 had solitary osteochondromas, 10 had multiple osteochondromas, 6 had a solitary enchondroma, 1 had Ollier's disease, and 1 had Maffucci's syndrome. The patient with Ollier's disease had two chondrosarcomas, and one patient with multiple osteochondroma had three chondrosarcomas. The cases were included in the study only when complete clinical documentation, radiological records, and histological analyses were available. RESULTS: The rate of malignant transformation for cartilage-originating tumors was 5.1% (solitary osteochondromas 4.2%, multiple osteochondromas 9.2%, solitary enchondromas 4.2%). The average time between the initial diagnosis and malignant transformation was 9.8 years. The most common site of involvement was the proximal portion of the femur. The tumors generally were well differentiated. The mean follow-up period was 57.3 months. Five patients (15.6%) died of tumor recurrence or metastasis at an average of 20.6 months. One patient is alive with tumor at 104 months. CONCLUSIONS: Cartilage-forming benign bone tumors are rather prone to undergo malignant transformation. Although malignant transformation of a benign bone tumor is a rarely encountered situation, orthopedic surgeons should be cautious while following patients with a benign bone neoplasm. Early recognition and appropriate surgical treatment are required to achieve successful outcomes. The rate of local recurrence in secondary chondrosarcomas depends not only on adequate surgical treatment but also on the localization and histological grade.


Asunto(s)
Neoplasias Óseas/patología , Cartílago/patología , Condrosarcoma/secundario , Neoplasias Primarias Secundarias/patología , Osteocondroma/patología , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Neoplasias Óseas/diagnóstico por imagen , Neoplasias Óseas/cirugía , Cartílago/diagnóstico por imagen , Transformación Celular Neoplásica/patología , Condrosarcoma/diagnóstico por imagen , Condrosarcoma/cirugía , Femenino , Humanos , Masculino , Persona de Mediana Edad , Recurrencia Local de Neoplasia , Neoplasias Primarias Secundarias/diagnóstico por imagen , Neoplasias Primarias Secundarias/cirugía , Osteocondroma/diagnóstico por imagen , Osteocondroma/cirugía , Radiografía , Estudios Retrospectivos
17.
Acta Orthop Traumatol Turc ; 41(1): 7-14, 2007.
Artículo en Turco | MEDLINE | ID: mdl-17483630

RESUMEN

OBJECTIVES: We compared the results of plate-screw fixation and intramedullary fixation with inflatable nails for the treatment of acute humeral diaphyseal fractures. METHODS: The study included 34 patients (20 females, 14 males; mean age 36.4 years; range 18 to 62 years) who were selected from patients treated with plate-screw fixation or inflatable intramedullary nails. The groups were matched for age, sex, severity of fracture, and the type of humeral fracture. Eighteen fractures were treated in each group. Classification of humeral fractures and open fractures were made according to the AO and Gustilo-Anderson systems, respectively. Functional evaluations were made at postoperative six and 12 months using Constant shoulder and Mayo elbow performance scores. All the patients were administered the Short-Form 36 (SF-36) questionnaire at 12 months. The two groups were compared with respect to operation time, perioperative need for blood transfusion, time to union, complications, and shoulder and elbow functions. RESULTS: The mean operation time was significantly shorter (25.3 min vs 66.1 min; p<0.001) and the need for blood transfusion was significantly less (p=0.001) with inflatable intramedullary nails. Constant shoulder and Mayo elbow scores did not differ significantly between the two groups. Implant failure was only encountered with plate-screw fixation in three patients. Union problems were observed in five patients (3 plate-screw, 2 intramedullary nail). Following plate-screw fixation, two patients developed superficial infection, two patients developed transient radial paralysis. CONCLUSIONS: Inflatable intramedullary nails can be used safely in the treatment of acute humeral diaphyseal fractures without increasing union problems and complications.


Asunto(s)
Clavos Ortopédicos , Placas Óseas , Diáfisis/cirugía , Fijación Interna de Fracturas/instrumentación , Fracturas del Húmero/cirugía , Adolescente , Adulto , Diáfisis/diagnóstico por imagen , Diáfisis/patología , Femenino , Humanos , Fracturas del Húmero/diagnóstico por imagen , Fracturas del Húmero/patología , Masculino , Persona de Mediana Edad , Complicaciones Posoperatorias , Radiografía , Rango del Movimiento Articular , Encuestas y Cuestionarios , Resultado del Tratamiento
19.
J Pediatr Orthop B ; 15(1): 28-33, 2006 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-16280716

RESUMEN

The clinical and conventional bi-planar determinations of femoral torsion were compared with the tomographic technique, the reliability of which was confirmed. Femoral torsions were measured with the trochanteric prominence angle test, the sinus-wave bi-planar conventional radiographic technique, the modified Hermann bi-planar conventional radiographic technique and the limited three-dimensional volumetric tomography technique in 34 femora of 17 patients. There was a strong correlation between the modified Hermann and the limited tomography techniques for 14 intact and 20 fractured femora. If limited three-dimensional volumetric tomography cannot be obtained, the modified Hermann bi-planar conventional radiographic technique must be used in patients who have scarring about the proximal femur and obesity. Otherwise use of the trochanteric prominence angle test is much more cost-effective and is as accurate as the limited three-dimensional volumetric tomography technique.


Asunto(s)
Fracturas del Fémur/diagnóstico por imagen , Fémur/diagnóstico por imagen , Adolescente , Niño , Preescolar , Fracturas del Fémur/terapia , Humanos , Imagenología Tridimensional , Análisis de Regresión , Tomografía Computarizada Espiral , Anomalía Torsional/diagnóstico por imagen
20.
Neurosciences (Riyadh) ; 11(2): 93-6, 2006 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-22266556

RESUMEN

OBJECTIVE: Histological examination of proliferative therapy effects on the healing process of muscular injury. METHODS: We performed this study between March and August 2002 at Ankara University, School of Medicine, Laboratory of Animal Experiments, Ankara, Turkey. We used an experimental animal model by conducting a standardized cut injury of the gastrocnemius muscle in 30 adult male albino rats, which we divided into 2 groups; proliferative therapy group and control group. We evaluated the injured rat muscles by light microscopy on the fifth, eight, and twelfth day of injury. RESULTS: The muscular regeneration process began at day 5 in both the control and proliferative therapy groups. The proliferative therapy group revealed a prominent inflammatory reaction, fibroblast migration, and necrosis with accompanying regeneration and excessive connective tissue formation. CONCLUSION: We cannot consider proliferative therapy an appropriate treatment modality for muscular injuries, unless there is evidence of normal muscle physiology and biomechanics post traumatically.

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