RESUMEN
Two patients with a history of epistaxis who were both found to have a nasolacrimal duct melanoma are presented. A literature review revealed that no previous cases of primary nasolacrimal duct melanoma have been reported. Current therapeutic modalities are discussed.
Asunto(s)
Neoplasias del Ojo/diagnóstico , Melanoma/diagnóstico , Conducto Nasolagrimal , Anciano , Epistaxis/etiología , Neoplasias del Ojo/complicaciones , Humanos , Masculino , Melanoma/complicaciones , Persona de Mediana Edad , Tomografía Computarizada por Rayos XRESUMEN
No disponible
Asunto(s)
Femenino , Adulto , Humanos , Linfedema/complicaciones , Enfermedades de la Uña/complicaciones , Tuberculosis/complicaciones , SíndromeRESUMEN
OBJECTIVE: To look for models predicting metastasis in laryngeal/hypopharyngeal carcinomas. DESIGN: Prospective study. PATIENTS: Sixty patients bearing laryngeal squamous cell carcinoma who were treated with curative purposes were followed prospectively with at least 10-year follow-up. PARAMETERS: Clinical (Staging, site, age, alcohol and smoking intake, surgery on the primary tumor, neck surgery) and pathological (size, number of metastatic lymph nodes, T and N staging, degree of differentiation, Jakobsson's and Glanz's scoring of malignancy, both scores in biopsies and surgical specimens) parameters were recorded in each case. METHODS: A multivariate analysis was performed to find out those parameters independently related to presence of metastases. RESULTS: The prospective study rendered tumor burden and Glanz's scoring from biopsies to be independently related with the presence of metastases. CONCLUSIONS: Malignancy grading systems must be included in laryngeal carcinoma patients' planning of neck treatment.
Asunto(s)
Carcinoma de Células Escamosas/patología , Neoplasias Laríngeas/patología , Carcinoma de Células Escamosas/radioterapia , Estudios de Seguimiento , Humanos , Neoplasias Laríngeas/radioterapia , Estadificación de Neoplasias/métodos , Pronóstico , Estudios ProspectivosRESUMEN
The leprosy is a chronic illness caused by M. leprae, which affects mucosa mainly at the level of the nasal region. The important destruction of the bone produces the facies leonina. We present the case of a patient with nasal leprosy, describing the clinical characteristics and the diagnostic and therapeutic methods that were carried out on her.
Asunto(s)
Lepra/diagnóstico , Enfermedades de los Cartílagos/etiología , Cara , Femenino , Humanos , Lepra/complicaciones , Persona de Mediana Edad , Tabique Nasal , Enfermedades Nasales/etiología , Trastornos de la Pigmentación/etiologíaRESUMEN
OBJECTIVE: To asses the role of Gastroesophageal reflux in the genesis of laryngeal granulomas. PATIENTS AND METHODS: Prospective series of 7 patients diagnosed of posterior laryngeal granuloma, 5 were male, and 2 female, ages ranging between 46 and 65 years, (only three with symptoms of gastroesophageal reflux), who followed an antireflux protocol (recommendations, omeprazol 20 mg, cisapride 20 mg, almagato 4000 mg daily). RESULTS: All cases did well, showing complete healing of the larynx 60 days after the beginning of treatment. CONCLUSIONS: Gastroesophageal reflux is an important factor in the genesis of posterior laryngeal granulomas. It seems appropriate to start an antireflux regimen before surgery, which can be chosen for non responders or cases with severe respiratory symptoms, hoarseness, or for definitive diagnosis.
