RESUMEN
BACKGROUND: Prospective studies about endoscopic retrograde cholangio-pancreatography (ERCP) in a community setting are rare. AIM: To assess success and complication rates of routinely-performed ERCP in a regional setting, and the priority quality indicators for ERCP practice. METHODS: Prospective region wide observational study on consecutive patients undergoing ERCP during a 6-month period. A centralized online ERCP questionnaire was built and used for data storage. Primary quality indicators provided by the American Society of Gastrointestinal Endoscopy (ASGE) were considered. RESULTS: 38 endoscopists from 18 centers performed a total of 2388 ERCP. The most common indication for ERCP was choledocholitiasis (54.8%) followed by malignant jaundice (22.6%). Cannulation of the desired duct was obtained in 2293 cases (96%) and ERCP was successful in 2176 cases (91.1%). Success and ERCP difficulty were significantly related to the experience of the operator (pâ¯=â¯0.001 and pâ¯<â¯0.001, respectively). ERCP difficulty was also significantly related to volume centers (pâ¯<â¯0.01). The overall complication rate was 8.4%: post-ERCP pancreatitis (PEP) occurred in 4.1% of procedures, bleeding in 2.9%, infection in 0.8%, perforation in 0.4%. Mortality rate was 0.4%. All the ASGE priority quality indicators for ERCP were confirmed. CONCLUSIONS: The procedural questionnaire proved to be an important tool to assess and verify the quality of routinely-performed ERCP performance in a community setting.
Asunto(s)
Colangiopancreatografia Retrógrada Endoscópica/efectos adversos , Colangiopancreatografia Retrógrada Endoscópica/estadística & datos numéricos , Hemorragia/epidemiología , Pancreatitis/epidemiología , Indicadores de Calidad de la Atención de Salud , Cateterismo/estadística & datos numéricos , Coledocolitiasis/diagnóstico por imagen , Coledocolitiasis/cirugía , Bases de Datos Factuales , Hemorragia/etiología , Humanos , Italia/epidemiología , Ictericia/diagnóstico por imagen , Modelos Logísticos , Pancreatitis/etiología , Estudios Prospectivos , Encuestas y CuestionariosAsunto(s)
Inhibidores Enzimáticos/uso terapéutico , Inmunoterapia/métodos , Melanoma/tratamiento farmacológico , Proteínas Proto-Oncogénicas B-raf/antagonistas & inhibidores , Neoplasias Gástricas/tratamiento farmacológico , Anciano , Anticuerpos Monoclonales/uso terapéutico , Endoscopía del Sistema Digestivo , Resultado Fatal , Humanos , Indoles/uso terapéutico , Ipilimumab , Imagen por Resonancia Magnética , Masculino , Melanoma/diagnóstico por imagen , Mutación , Proteínas Proto-Oncogénicas B-raf/genética , Neoplasias Gástricas/diagnóstico por imagen , Sulfonamidas/uso terapéutico , Tomografía Computarizada por Rayos X , VemurafenibRESUMEN
Splenic rupture is a rare complication of diagnostic and therapeutic gastrointestinal endoscopy procedures. Herein, we report for the first time a case of splenic rupture following therapeutic retrograde double-balloon enteroscopy, which occurred in an 85-year-old man who was treated for recurrent mid-intestinal bleeding that resulted from ileal angioectasia. This patient promptly underwent an operation and eventually recovered.
Asunto(s)
Toma de Decisiones Clínicas/métodos , Examen Físico/normas , Adulto , Humanos , Masculino , Sífilis/diagnósticoAsunto(s)
Hemorragia Gastrointestinal/etiología , Íleon/irrigación sanguínea , Malformaciones Vasculares/diagnóstico , Arterias/anomalías , Endoscopía Capsular , Humanos , Masculino , Persona de Mediana Edad , Resultado del Tratamiento , Malformaciones Vasculares/complicaciones , Malformaciones Vasculares/cirugíaRESUMEN
BACKGROUND: Submucosal malignant masses (SMMs) and innocent bulges look similar on small-bowel capsule endoscopy (SBCE). In a previous observational study, 4 criteria associated with innocent bulges were recognized. OBJECTIVE: To devise and validate an index based on these criteria (smooth, protruding lesion index on capsule endoscopy [SPICE]) to discriminate SMMs from innocent bulges. DESIGN: Single-center, prospective study. SETTING: General hospital in Busto Arsizio, Italy. PATIENTS: This study involved 25 of 424 consecutive SBCEs performed on as many patients having SBCE findings of smooth, round, protruding lesions. INTERVENTION: Patients' evaluation up to the final diagnosis. At study entry, a short video clip of the lesion was obtained and deidentified for blind SPICE calculation. MAIN OUTCOME MEASUREMENTS: SPICE accuracy, using the final diagnosis of each patient as the criterion standard. RESULTS: Six patients had SMMs (4 GI stromal tumors, 2 neuroendocrine tumors), and 19 had innocent bulges. SPICE scores ranged from 0 to 4; they discriminated SMMs from innocent bulges (P = .002). A SPICE value >2 had 83.3% sensitivity and 89.4% specificity, and the area under the curve was 0.90 (95% confidence interval, 0.72-0.98; P < .001) for the detection of SMMs. LIMITATIONS: Single-center study; small sample size; no invasive ascertainment in 36% of patients. CONCLUSION: SPICE is easy to calculate and useful for distinguishing SMMs from innocent bulges. An index >2 is predictive of SMM.
Asunto(s)
Endoscopía Capsular , Técnicas de Apoyo para la Decisión , Tumores del Estroma Gastrointestinal/patología , Neoplasias del Íleon/patología , Neoplasias del Yeyuno/patología , Tumores Neuroendocrinos/patología , Adulto , Anciano , Anciano de 80 o más Años , Área Bajo la Curva , Malformaciones Arteriovenosas/patología , Femenino , Humanos , Enfermedades del Íleon/patología , Síndrome del Colon Irritable/patología , Enfermedades del Yeyuno/patología , Masculino , Persona de Mediana Edad , Variaciones Dependientes del Observador , Estudios Prospectivos , Curva ROC , Estadísticas no Paramétricas , Adherencias Tisulares/patologíaRESUMEN
Endoscopic palliation is the most suitable approach to improve quality of life in patients with esophageal cancer since diagnosis is often made at an advanced stage, when radical treatment is unfeasible. Endoscopy offers several techniques to palliate dysphagia either by stenting the stenosis or by reducing the tumor mass with thermoablation. A small number of randomized controlled trials is available to compare the efficacy of different techniques and the ideal palliation has not been defined as yet. Recently, the development of self-expandable covered metal stents has rapidly gained ground in the endoscopy units throughout the world as a simple, single step procedure for palliation of dysphagia.