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Nucleic Acids Res ; 38(Database issue): D308-17, 2010 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-19858099

RESUMEN

The Protein Data Bank in Europe (PDBe) (http://www.ebi.ac.uk/pdbe/) is actively working with its Worldwide Protein Data Bank partners to enhance the quality and consistency of the international archive of bio-macromolecular structure data, the Protein Data Bank (PDB). PDBe also works closely with its collaborators at the European Bioinformatics Institute and the scientific community around the world to enhance its databases and services by adding curated and actively maintained derived data to the existing structural data in the PDB. We have developed a new database infrastructure based on the remediated PDB archive data and a specially designed database for storing information on interactions between proteins and bound molecules. The group has developed new services that allow users to carry out simple textual queries or more complex 3D structure-based queries. The newly designed 'PDBeView Atlas pages' provide an overview of an individual PDB entry in a user-friendly layout and serve as a starting point to further explore the information available in the PDBe database. PDBe's active involvement with the X-ray crystallography, Nuclear Magnetic Resonance spectroscopy and cryo-Electron Microscopy communities have resulted in improved tools for structure deposition and analysis.


Asunto(s)
Biología Computacional/métodos , Bases de Datos Genéticas , Bases de Datos de Proteínas , Secuencia de Aminoácidos , Animales , Sitios de Unión , Biología Computacional/tendencias , Europa (Continente) , Humanos , Almacenamiento y Recuperación de la Información/métodos , Internet , Ligandos , Datos de Secuencia Molecular , Estructura Terciaria de Proteína , Homología de Secuencia de Aminoácido , Programas Informáticos
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