RELATIONSHIP OF DERMATOGLYPHICS WITH SPEED OF REACTION AND TYPE OF TEMPERAMENT OF ATHLETICS.

OBJECTIVE: The aim: To establish and practically substantiate the relationship between dermatoglyphic markers and the speed of reaction and type of temperament of track and field athletes. PATIENTS AND METHODS: Materials and methods: Analysis of scientific and methodological literature, survey, dermatoglyphics, methods of mathematical and statistical processing of the received data. RESULTS: Results: Track and field athletes among the population of the Sumy region of Ukraine have a tendency to decrease the number of whorls (p<0.05). Athletes of the sanguine type of temperament are most common (67,6%), and in the control group (among students of a medical university) the phlegmatic type of temperament is most common (68,4%). Also, among the subjects of the main group there is no such temperament as melancholic. We also determined the ATD angle for the palm. It was 37±4.88 in the main group, and 47±3.11 in the control group. This indicates a hereditary predisposition of this trait. The delta index in the control group has lower values (DI=9.5) than in the main group (DI=13.3). CONCLUSION: Conclusions: We established and practically substantiated the relationship between dermatoglyphic markers and reaction speed and temperament type of track and field athletes. Determined the relationship between the anatomical features of the fingers and the speed of mastering movements. For track and field athletes of the population of Ukraine, there were characteristic features of the dermatoglyphic structure: higher values of the deltoid index and genetic markers of the distance between the triradii a and d of the fingers.

[The analysis of association between ENPP1 K121Q polymorphism and risk factors of type 2 diabetes mellitus in ukrainian population].

OBJECTIVE: Introduction: More than 100 genes have been described associations between single nucleotide polymorphisms and type 2 diabetes mellitus (T2DM). Among these candidate genes, Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 (ENPP1), is located on the long arm of chromosome 6 (6q23.2) and encodes for a protein which is one of the factors determining the insulin sensitivity. An allelic polymorphism in exon 4 of ENPP1 (rs1044498) has been designated K121Q and widely investigated in T2DM in different populations. The aim: To analyze the association between ENPP1 K121Q polymorphism with the risk factors of type 2 diabetes mellitus in the Ukrainian population. PATIENTS AND METHODS: Materials and methods: Venous blood of 317 patients with type 2 diabetes mellitus and 302 controls was used for analysis. ENPP1 K121Q genotyping was performed using PCR-RFLP method. RESULTS: Results: Our results revealed that ratio of K/K homozygotes, K/Q heterozygotes and Q/Q homozygotes between case and control groups was significantly different (59.3%, 34.1%, 6.6% vs 67.9%, 28.5%, 3.6%, P = 0.05). Method of binary logistic regression shown that a reliable relationship was established in the general group for KQ/QQ vs K/K genetic model (P = 0.027). It was shown that in carriers of the minor Q-allele, the risk of T2DM is 1.4x higher than in homozygotes in the main K-allele (95% CI = 1.043-2.016). After adjusting for age, sex, smoking habit, BMI, obesity and the presence of hypertension, the reliability of these results persisted (P = 0.026). CONCLUSION: Conclusions: ENPP1 K121Q polymorphism is associated with T2DM in Ukrainian population. In carriers of the minor Q-allele the risk of T2DM is 1.4x higher than in homozygotes in the main K-allele. The risk increases in patients with BMI ≥ 25 kg/m2.