Combination Therapy of Antibiotics and Platelet-rich Fibrin for Apical Closure: Case Series.

The aim of endodontic treatment in immature teeth is to disinfect and regenerate tissues in the apical region for the closure of the root. Stem cells from apical papilla (SCAP) by differentiating into odontogenic and osteogenic tissues create apical closure. Triple antibiotic pastes (TAP) disinfect the root canal without adversely affecting the SCAP. Differentiation of SCAP is promoted by platelet-rich fibrin (PRF). Hence, combining TAP and PRF could have a synergistic effect. Case description: An 11-year-old girl, a 9-year-old boy, and a 13-year-old boy, symptomatic patients with open apex, are treated with TAP, PRF, and mineral trioxide aggregate (MTA) as an apical barrier sequentially. There was the formation of a calcific barrier at the end of 12, 6, and 3 months, respectively. Conclusion: Correct diagnosis and protocol of sequential disinfection, regeneration, and finally filling the canal with an apical barrier could yield better results. How to cite this article: Biradar N, Ragulakollu R, Tej G, et al. Combination Therapy of Antibiotics and Platelet-rich Fibrin for Apical Closure: Case Series. Int J Clin Pediatr Dent 2023;16(3):541-546.

The prevalence of depression, anxiety, and stress among high school adolescent's children in public and private schools in Rangareddy district Telangana state: A cross-sectional study.

BACKGROUND: The depression, anxiety, and stress is a major educational problem among students all around the world. The purposes of this study were to determine the depression, anxiety, and stress among the high school adolescent children in public and private schools in Rangareddy district, Telangana state. MATERIALS AND METHODS: The present study was a cross-sectional study. The study sample considered 120 children from private schools and 259 children from public schools were studied. The study tool used was a questionnaire containing DASS (Depression, Anxiety, and Stress scale and sociodemographic characteristics. The data were expressed as proportion and mean values (Analysis of variance, independed t-test, and Pearson correlation) spatially tests were used at a significance level of P < 0.05). RESULTS: The overall prevalence of depression in children from the public school was found to be only 5%, that of anxiety was 20.8%, and that of stress was 15.8%; the overall prevalence of depression in children from private schools was found to be 1.9%, that of anxiety was 20.5%, and that of stress was 20.1%. CONCLUSION: In both schools, anxiety and atress were found to be more among study participants. Depression was observed to be less. But if they have more anxiety and stress and if not taken proper care at this point of time, it might get converted into a state of Depression.

Role of Plasma-rich Fibrin in the Management of Intrusion Injuries of Teeth.

AIM AND OBJECTIVE: To establish a new method of treating severe type of intrusion type of injuries to teeth. The prognosis of these injuries is poor. Poor prognosis is attributed to the development of multiple complications from various components of teeth. We described the various phases to prevent and treat various complications. BACKGROUND: Most common sequelae to intrusion injuries are alveolar bone loss, resorption of teeth, and gingival recession. Plasma-rich fibrin (PRF) possesses various biological elements for optimal healing and prevention of the above. CASE DESCRIPTION: A 9-year-old female patient suffered intrusion injury to 21 with no root fractures. Since intrusion was severe type, surgical repositioning with flexible splinting is done. Complications such as alveolar bone loss and gingival recession have occurred, which were successfully treated with PRF. To prevent development of resorption, calcium hydroxide was used as intracanal medicament and doxycycline was used to prevent surface resorption. CONCLUSION: PRF is effective not only in promoting healing, bone deposition but also prevents secondary infection of the wound. Hence, it is simple, easy, and inexpensive biomaterial for treating intrusion injuries of teeth. CLINICAL SIGNIFICANCE: Considering the various properties associated with PRF, it could be a key for treating other type traumatic injuries to teeth. HOW TO CITE THIS ARTICLE: Ragulakollu R, Biradar N, Kukkunuru GT, et al. Role of Plasma-rich Fibrin in the Management of Intrusion Injuries of Teeth. Int J Clin Pediatr Dent 2021;14(6):820-824.

Evaluation of Marginal Adaptation of Composite Restorations Reinforced with Novel Enamel Inserts (Biofillers) in Class V Cavities.

AIM AND OBJECTIVE: To evaluate the marginal adaptation at the tooth-restoration interface at enamel and cementum margins using composite restoration reinforced with novel enamel inserts/biofillers. MATERIALS AND METHODS: Standardized class V box-shaped cavities were prepared in 40 extracted maxillary first premolar teeth which were divided randomly into four experimental groups consisting of 10 samples each. Group I: Bulk placement. Groups II: Horizontal incremental technique. Group III: Restoration with precured composite balls (megafillers). Group IV: Restoration with biofillers. All the cavities were restored with visible light-activated direct restorative nanocomposite. The specimens were thermocycled for 24 hours. After thermocycling, the samples were immersed in a 1% methylene blue for 4 hours and subsequently evaluated for microleakage. Microleakage scores (0-4) were obtained from gingival margins of class V restorations and analyzed by statistical analysis. Evaluation of the data was performed by Kruskal-Wallis one-way analysis of variance (ANOVA), and Mann-Whitney U tests. RESULTS: Microleakage scores have indicated restorations with biofillers showed best results followed by megafillers, incremental horizontal build-up, and bulk filling. CONCLUSION: Biofillers provide a novel approach in improving microleakage and marginal adaptability of composite resin restorations. CLINICAL SIGNIFICANCE: Incorporation of inserts, which are capable of adequate bonding to resin and tooth, may provide improved marginal adaptability and reduce microleakage around restorative margins.

Endodontic treatment of mandibular canine with two roots and two canals.

In majority of cases, mandibular canines have one root and one root canal, although 15% may have two canals. Literature report shows incidence of two-rooted canine as low as 1.7%. This article reports a clinical case of endodontic treatment of mandibular canine with two roots and two canals.