Targeted Engagement of the Action Selection Network during Task-Oriented Arm Training after Stroke.

Action selection (AS), or selection of an action from a set of alternatives, is an important movement preparation process that engages a frontal-parietal network. The addition of AS demands to arm training after stroke could be used to engage this motor planning process and the neural network that supports it. The purpose of this case series is to describe the feasibility and outcomes associated with task-oriented arm training aimed at engaging the AS behavioral process and the related neural network in three individuals with chronic stroke. Three participants with mild to moderate motor deficits completed 13 to 15 sessions of task-oriented arm training that included AS cues for each movement repetition; cues dictated movement direction, height, or distance. Before and after training, individuals completed an AS brain-behavior probe during functional MRI. AS behavioral performance improved after training (increased accuracy, decreased reaction time) in all participants while brain activation in the AS network (dorsal premotor, parietal, dorsolateral prefrontal cortices) decreased in two participants. Gains in motor function were also found in all three participants, especially on patient-reported measures of perceived difficulty and confidence to complete upper extremity functional tasks. It was feasible to target the AS behavioral process and the related neural network through the addition of AS demands to functional, task-oriented arm training in three individuals with mild to moderate motor dysfunction poststroke.

Body weight-supported treadmill training is no better than overground training for individuals with chronic stroke: a randomized controlled trial.

BACKGROUND: Body weight-supported treadmill training (BWSTT) has produced mixed results compared with other therapeutic techniques. OBJECTIVE: The purpose of this study was to determine whether an intensive intervention (intensive mobility training) including BWSTT provides superior gait, balance, and mobility outcomes compared with a similar intervention with overground gait training in place of BWSTT. METHODS: Forty-three individuals with chronic stroke (mean [SD] age, 61.5 [13.5] years; mean [SD] time since stroke, 3.3 [3.8] years), were randomized to a treatment (BWSTT, n = 23) or control (overground gait training, n = 20) group. Treatment consisted of 1 hour of gait training; 1 hour of balance activities; and 1 hour of strength, range of motion, and coordination for 10 consecutive weekdays (30 hours). Assessments (step length differential, self-selected and fast walking speed, 6-minute walk test, Berg Balance Scale [BBS], Dynamic Gait Index [DGI], Activities-specific Balance Confidence [ABC] scale, single limb stance, Timed Up and Go [TUG], Fugl-Meyer [FM], and perceived recovery [PR]) were conducted before, immediately after, and 3 months after intervention. RESULTS: No significant differences (α = 0.05) were found between groups after training or at follow-up; therefore, groups were combined for remaining analyses. Significant differences (α = 0.05) were found pretest to posttest for fast walking speed, BBS, DGI, ABC, TUG, FM, and PR. DGI, ABC, TUG, and PR results remained significant at follow-up. Effect sizes were small to moderate in the direction of improvement. CONCLUSIONS: Future studies should investigate the effectiveness of intensive interventions of durations greater than 10 days for improving gait, balance, and mobility in individuals with chronic stroke.

Concurrent validity of walking speed values calculated via the GAITRite electronic walkway and 3 meter walk test in the chronic stroke population.

The purpose of this study was to provide novel information regarding the concurrent validity (primary aim) and reliability (secondary aim) of walking speed (WS) calculated via the GAITRite electronic walkway system and 3 meter walk test (3MWT) in the chronic stroke population. The 3MWT is a feasible option for clinicians working in environments where space is limited. Psychometric properties of the test have not been established. Participants with chronic stroke were stratified into three groups: (1) household ambulators (HA) (self-selected WS < 0.4 m/s, 12 participants, 31 observations); (2) limited community ambulators (LCA) (self-selected WS 0.4-0.8 m/s, 24 participants, 60 observations); and (3) community ambulators (CA) (self-selected WS > 0.8 m/s, 26 participants, 71 observations). Three consecutive trials of GAITRite and 3MWT were performed at participant's self-selected WS. Average WS measurements differed significantly (p < 0.05) between GAITRite and 3MWT for all three groups. HA group: GAITRite 0.25 (0.11) m/s, 3MWT 0.27 (0.11) m/s; LCA group: GAITRite 0.56 (0.11) m/s, 3MWT 0.52 (0.10) m/s; CA group: GAITRite 1.03 (0.16) m/s, 3MWT 0.89 (0.15) m/s. Both WS measures had excellent within-session reliability (ICC's ranging from 0.85 to 0.97, SEM95 from 0.04 to 0.12 m/s and MDC95 from 0.05 to 0.16 m/s). Reliability was highest for HA on both measures. Although both the 3MWT and the GAITRite are reliable measures of WS for individuals with chronic stroke, the two measures do not demonstrate concurrent validity.