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Intensive longitudinal research-including experience sampling and smartphone sensor monitoring-has potential for identifying proximal risk factors for psychopathology, including suicidal thoughts and behaviors (STB). Yet, missing data can complicate analysis and interpretation. This study aimed to address whether clinical and study design factors are associated with missing data and whether missingness predicts changes in symptom severity or STB. Adolescents ages 13- to 18 years old (N = 179) reporting depressive, anxiety, and/or substance use disorders were enrolled; 65% reported current suicidal ideation and 29% indicated a past-year attempt. Passively acquired smartphone sensor data (e.g., global positioning system, accelerometer, and keyboard inputs), daily mood surveys, and weekly suicidal ideation surveys were collected during the 6-month study period using the effortless assessment research system smartphone app. First, acquisition of passive smartphone sensor data (with data on â¼80% of days across the whole sample) was strongly associated with survey data acquisition on the same day (â¼44% of days). Second, STB and psychiatric symptoms were largely not associated with missing data. Rather, temporal features (e.g., length of time in study, weekends, and summer) explained more missingness of survey and passive smartphone sensor data. Last, within-participant changes in missing data over time neither followed nor predicted subsequent change in suicidal ideation and psychiatric symptoms. Findings indicate that considering technical and study design factors impacting missingness is critical and highlight several factors that should be addressed to maximize the validity of clinical interpretations in intensive longitudinal research. (PsycInfo Database Record (c) 2024 APA, all rights reserved).
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Our understanding of ownership influences how we interact with objects and with each other. Here, we studied people's intuitions about ownership transfer using a set of simple, parametrically varied events. We found that people (N = 120 U.S. adults) had similar intuitions about ownership for some events but sharply opposing intuitions for others (Experiment 1). People (N = 120 U.S. adults) were unaware of these conflicts and overestimated ownership consensus (Experiment 2). Moreover, differences in people's ownership intuitions predicted their intuitions about the acceptability of using, altering, controlling, and destroying the owned object (N = 130 U.S. adults; Experiment 3), even when ownership was not explicitly mentioned (N = 130 U.S. adults; Experiment 4). Subject-level analyses suggest that these disagreements reflect at least two underlying intuitive theories, one in which intentions are central to ownership and another in which physical possession is prioritized.
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Intuición , Propiedad , Humanos , Adulto , Femenino , Masculino , Adulto Joven , Juicio , IntenciónRESUMEN
Cognitive science has demonstrated that we construct knowledge about the world by abstracting patterns from routinely encountered experiences and storing them as semantic memories. This preregistered study tested the hypothesis that caregiving-related early adversities (crEAs) shape affective semantic memories to reflect the content of those adverse interpersonal-affective experiences. We also tested the hypothesis that because affective semantic memories may continue to evolve in response to later-occurring positive experiences, child-perceived attachment security will inform their content. The sample comprised 160 children (ages 6-12 at Visit 1; 87F/73 M), 66% of whom experienced crEAs (n = 105). At Visit 1, crEA exposure prior to study enrollment was operationalized as parental-reports endorsing a history of crEAs (abuse/neglect, permanent/significant parent-child separation); while child-reports assessed concurrent attachment security. A false memory task was administered online â¼2.5 years later (Visit 2) to probe the content of affective semantic memories-specifically attachment schemas. Results showed that crEA exposure (vs. no exposure) was associated with a higher likelihood of falsely endorsing insecure (vs. secure) schema scenes. Attachment security moderated the association between crEA exposure and insecure schema-based false recognition. Findings suggest that interpersonal-affective semantic schemas include representations of parent-child interactions that may capture the quality of one's own attachment experiences and that these representations shape how children remember attachment-relevant narrative events. Findings are also consistent with the hypothesis that these affective semantic memories can be modified by later experiences. Moving forward, the approach taken in this study provides a means of operationalizing Bowlby's notion of internal working models within a cognitive neuroscience framework. RESEARCH HIGHLIGHTS: Affective semantic memories representing insecure schema knowledge (child needs + needs-not-met) may be more salient, elaborated, and persistent among youths exposed to early caregiving adversity. All youths, irrespective of early caregiving adversity exposure, may possess affective semantic memories that represent knowledge of secure schemas (child needs + needs-met). Establishing secure relationships with parents following early-occurring caregiving adversity may attenuate the expression of insecure semantic memories, suggesting potential malleability. Affective semantic memories include schema representations of parent-child interactions that may capture the quality of one's own attachment experiences and shape how youths remember attachment-relevant events.
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Many scholars have proposed that feeling what we believe others are feeling-often known as "empathy"-is essential for other-regarding sentiments and plays an important role in our moral lives. Caring for and about others (without necessarily sharing their feelings)-often known as "compassion"-is also frequently discussed as a relevant force for prosocial motivation and action. Here, we explore the relationship between empathy and compassion using the methods of computational linguistics. Analyses of 2,356,916 Facebook posts suggest that individuals (N = 2,781) high in empathy use different language than those high in compassion, after accounting for shared variance between these constructs. Empathic people, controlling for compassion, often use self-focused language and write about negative feelings, social isolation, and feeling overwhelmed. Compassionate people, controlling for empathy, often use other-focused language and write about positive feelings and social connections. In addition, high empathy without compassion is related to negative health outcomes, while high compassion without empathy is related to positive health outcomes, positive lifestyle choices, and charitable giving. Such findings favor an approach to moral motivation that is grounded in compassion rather than empathy. (PsycInfo Database Record (c) 2024 APA, all rights reserved).
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Emociones , Empatía , Humanos , Motivación , Principios Morales , LingüísticaRESUMEN
In this article we investigate the societal implications of empathic artificial intelligence (AI), asking how its seemingly empathic expressions make people feel. We highlight AI's unique ability to simulate empathy without the same biases that afflict humans. While acknowledging serious pitfalls, we propose that AI expressions of empathy could improve human welfare.
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Inteligencia Artificial , Empatía , Humanos , EmocionesRESUMEN
These guidelines present a systematic approach to diagnosis, treatment, and management of allergic skin diseases in dogs and cats. The guidelines describe detailed diagnosis and treatment plans for flea allergy, food allergy, and atopy in dogs and for flea allergy, food allergy, and feline atopic skin syndrome in cats. Management of the allergic patient entails a multimodal approach with frequent and ongoing communication with the client. Obtaining a comprehensive history is crucial for diagnosis and treatment of allergic skin diseases, and the guidelines describe key questions to ask when presented with allergic canine and feline patients. Once a detailed history is obtained, a physical examination should be performed, a minimum dermatologic database collected, and treatment for secondary infection, ectoparasites, and pruritus (where indicated) initiated. The process of diagnosing and managing allergic skin disease can be prolonged and frustrating for clients. The guidelines offer recommendations and tips for client communication and when referral to a dermatologist should be considered, to improve client satisfaction and optimize patient outcomes.
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Enfermedades de los Gatos , Dermatitis Atópica , Enfermedades de los Perros , Hipersensibilidad a los Alimentos , Humanos , Animales , Gatos , Perros , Dermatitis Atópica/diagnóstico , Dermatitis Atópica/terapia , Dermatitis Atópica/veterinaria , Enfermedades de los Gatos/diagnóstico , Enfermedades de los Gatos/terapia , Enfermedades de los Perros/diagnóstico , Enfermedades de los Perros/terapia , Prurito/terapia , Prurito/veterinaria , Hipersensibilidad a los Alimentos/veterinaria , AlérgenosRESUMEN
BACKGROUND: Adolescence is characterized by a heightened vulnerability for Major Depressive Disorder (MDD) onset, and currently, treatments are only effective for roughly half of adolescents with MDD. Accordingly, novel interventions are urgently needed. This study aims to establish mindfulness-based real-time fMRI neurofeedback (mbNF) as a non-invasive approach to downregulate the default mode network (DMN) in order to decrease ruminatory processes and depressive symptoms. METHODS: Adolescents (N = 90) with a current diagnosis of MDD ages 13-18-years-old will be randomized in a parallel group, two-arm, superiority trial to receive either 15 or 30 min of mbNF with a 1:1 allocation ratio. Real-time neurofeedback based on activation of the frontoparietal network (FPN) relative to the DMN will be displayed to participants via the movement of a ball on a computer screen while participants practice mindfulness in the scanner. We hypothesize that within-DMN (medial prefrontal cortex [mPFC] with posterior cingulate cortex [PCC]) functional connectivity will be reduced following mbNF (Aim 1: Target Engagement). Additionally, we hypothesize that participants in the 30-min mbNF condition will show greater reductions in within-DMN functional connectivity (Aim 2: Dosing Impact on Target Engagement). Aim 1 will analyze data from all participants as a single-group, and Aim 2 will leverage the randomized assignment to analyze data as a parallel-group trial. Secondary analyses will probe changes in depressive symptoms and rumination. DISCUSSION: Results of this study will determine whether mbNF reduces functional connectivity within the DMN among adolescents with MDD, and critically, will identify the optimal dosing with respect to DMN modulation as well as reduction in depressive symptoms and rumination. TRIAL REGISTRATION: This study has been registered with clinicaltrials.gov, most recently updated on July 6, 2023 (trial identifier: NCT05617495).
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Trastorno Depresivo Mayor , Atención Plena , Neurorretroalimentación , Humanos , Adolescente , Trastorno Depresivo Mayor/diagnóstico por imagen , Trastorno Depresivo Mayor/terapia , Imagen por Resonancia Magnética/métodos , Neurorretroalimentación/métodos , Giro del Cíngulo/diagnóstico por imagen , Encéfalo/diagnóstico por imagen , Mapeo Encefálico/métodosRESUMEN
Significant advances have been made in recent years regarding the developmental trajectories of brain circuits and networks, revealing links between brain structure and function. Emerging evidence highlights the importance of developmental trajectories in determining early psychiatric outcomes. However, efforts to encourage crosstalk between basic developmental neuroscience and clinical practice are limited. Here, we focus on the potential advantage of considering features of neural circuit development when optimizing treatments for adolescent patient populations. Drawing on characteristics of adolescent neurodevelopment, we highlight two examples, safety cues and incentives, that leverage insights from neural circuit development and may have great promise for augmenting existing behavioral treatments for anxiety disorders during adolescence. This commentary seeks to serve as a framework to maximize the translational potential of basic research in developmental populations for strengthening psychiatric treatments. In turn, input from clinical practice including the identification of age-specific clinically relevant phenotypes will continue to guide future basic research in the same neural circuits to better reflect clinical practices. Encouraging reciprocal communication to bridge the gap between basic developmental neuroscience research and clinical implementation is an important step toward advancing both research and practice in this domain.
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OBJECTIVE: In the current project, we focus on another group of unusual altruists: people who have taken the Giving What We Can (GWWC) pledge to donate at least 10% of their income to charity. Our project aims to understand what is unique about this population. BACKGROUND: Many people care about helping, but in recent years there has been a surge of research examining those whose moral concern for others goes far beyond that of the typical population. These unusual altruists (also termed extraordinary or extreme altruists or moral exemplars) make great personal sacrifices to help others-such as donating their kidneys to strangers or participating in COVID-19 vaccine challenge trials. METHOD: In a global study (N = 536) we examine a number of cognitive and personality traits of GWWC pledgers and compare them to a country-matched comparison group. RESULTS: In accordance with our predictions, GWWC pledgers were better at identifying fearful faces, more morally expansive and higher in actively open-minded thinking, need for cognition and two subscales of utilitarianism and, tentatively, lower in social dominance orientation. Against our predictions, they were lower in maximizing tendency. Finally, we found an inconclusive relationship between pledger status and empathy/compassion that we believe warrants further examination. CONCLUSIONS: These findings offer initial insights into the characteristics that set apart those who have made the decision to donate a substantial portion of their income to help others.
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Familiar music facilitates memory retrieval in adults with dementia. However, mechanisms behind this effect, and its generality, are unclear because of a lack of parallel work in healthy aging. Exposure to familiar music enhances spontaneous recall of memories directly cued by the music, but it is unknown whether such effects extend to deliberate recall more generally - e.g., to memories not directly linked to the music being played. It is also unclear whether familiar music boosts recall of specific episodes versus more generalised semantic memories, or whether effects are driven by domain-general mechanisms (e.g., improved mood). In a registered report study, we examined effects of familiar music on deliberate recall in healthy adults ages 65-80 years (N = 75) by presenting familiar music from earlier in life, unfamiliar music, and non-musical audio clips across three sessions. After each clip, we assessed free recall of remote memories for pre-selected events. Contrary to our hypotheses, we found no effects of music exposure on recall of prompted events, though familiar music evoked spontaneous memories most often. These results suggest that effects of familiar music on recall may be limited to memories specifically evoked in response to the music (Preprint and registered report protocol at https://osf.io/kjnwd/).
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Envejecimiento Saludable , Memoria Episódica , Humanos , Adulto , Anciano , Anciano de 80 o más Años , Semántica , Recuerdo Mental/fisiología , Señales (Psicología)RESUMEN
Malassezia pachydermatis is a commensal of canines associated with Malassezia dermatitis. Consensus guidelines recommend topical and/or systemic treatment, but resistance to antifungals has been reported. The objective of this pilot study was to determine the efficacy of a 0.003% colloidal silver nanoparticle-based shampoo in the treatment of canine Malassezia dermatitis. Dogs were included based on compatible history, presentation, and at least one positive cytology. Fourteen privately owned dogs were bathed every 48 hr for up to 28 days, allowing 5-10 min of contact time. The mean Malassezia organisms for 10 oil immersion fields at each Malassezia dermatitis-affected body area was recorded at days 0 and 14. Dogs positive on day 14 had cytologies performed on day 28. Eleven dogs (78.6%) were cytologically negative by day 28. Nine (81.8%) of these were negative by day 14. One dog (7.14%) had partial resolution (negative in 3/4 Malassezia dermatitis areas) by day 28. These results suggest that silver nanoparticle-based shampoo may be effective in the treatment of canine Malassezia dermatitis. Larger, controlled studies are needed to further investigate efficacy, optimal concentration, and ideal application frequency.
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Dermatitis , Dermatomicosis , Enfermedades de los Perros , Malassezia , Nanopartículas del Metal , Perros , Animales , Proyectos Piloto , Plata/uso terapéutico , Dermatomicosis/tratamiento farmacológico , Dermatomicosis/veterinaria , Nanopartículas del Metal/uso terapéutico , Enfermedades de los Perros/tratamiento farmacológico , Dermatitis/veterinariaRESUMEN
The tip-of-the-tongue (TOT) state is a spontaneously occurring metacognitive state that indicates that the answer to a query is almost, but not quite, at hand, i.e., that resolution is imminent. Since the time of William James, a distinctive feeling of nagging frustration has been observed to be associated with TOT states. On a more positive note, TOT states are also associated with intense goal-directed curiosity and with a strong desire to know that translates into successful mental action. The present study showed that prior to the presentation of resolving feedback to verbal queries-if the individual was in a TOT state-alpha suppression was in evidence in the EEG. This alpha suppression appears to be a marker of a spontaneously occurring, conscious, and highly motivating goal-directed internal metacognitive state. At the same time, alpha expression in the same time period was associated with the feeling of not knowing, indicating a more discursive state. Both alpha and alpha suppression were observed broadly across centro-parietal scalp electrodes and disappeared immediately upon presentation of the resolving feedback. Analyses indicated that the occurrence of alpha suppression was associated with participants' verbal affirmations of being in a TOT state, which is also related to subsequent expression of a late positivity when feedback is provided, and to enhanced memory.
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Adults often prefer things that they believe are natural, including natural foods. This preference has serious implications, such as the rejection of cultured meat and other sustainable technologies. Here we explore whether children also prefer natural foods. We conducted two preregistered studies with 374 adults and children from the United States. In Study 1, children's (N = 120) ages ranged from 6-10 years, with 57% of the sample identifying as female identifying as White/European American, whereas adults (N = 120) had a mean age of 30 years and 4 months, with 48.7% identifying as female, and 69.2% identifying as White/European American. In Study 2, children's (N = 63) aged ranged from 5-7 years, with 57% identifying as female and 66% identifying as White/European American, whereas adults (N = 64) had a mean age of 29 years and 11 months, with 60.7% of the sample identifying as female and 59% of participants identifying as White/European American. We found that, like adults, American children of these ages prefer natural over unnatural foods. This was found across two domains (fruit, juice) and a range of measures (tastiness, safety, unnaturalness, desire to consume). This preference was found in children as young as 5 years of age. Overall, we provide evidence that, at least in the United States, our tendency to prefer natural food is present even in childhood. (PsycInfo Database Record (c) 2022 APA, all rights reserved).
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Preferencias Alimentarias , Población Blanca , Adulto , Niño , Preescolar , Femenino , Preferencias Alimentarias/etnología , Humanos , Masculino , Estados Unidos , Población Blanca/psicología , Población Blanca/estadística & datos numéricosRESUMEN
Past research has demonstrated that both consequentialist motives (such as deterrence) and deontological motives (such as "just deserts") underlie children's and adults' punitive behavior. But what motives do we ascribe to others who pursue punishment? The present work explores this question by assessing which punitive motives children (6- and 7-year-olds, n = 100; 67% White; 55% female) and adults (n = 100; 76% White; 35% female) attribute to individuals who witnessed and punished a transgression (third-party punishment). Beyond this, we varied the social role of the punisher (a teacher, an adult visiting a school, a fellow peer) to examine whether motivational ascriptions vary depending on social context. Across these contexts, children endorsed a variety of punishment motives but consistently rejected the notion that individuals punish for the purpose of inflicting suffering. Adults-like children-prioritized consequentialist motives but, in more personal contexts (involving a child punishing their peer), considered "just deserts" a more plausible motive. These findings speak to developmental and contextual variation in individuals' theories about punitive motives and provide insight into how individuals understand and respond to punishment in everyday life. (PsycInfo Database Record (c) 2022 APA, all rights reserved).
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Motivación , Castigo , Adulto , Niño , Femenino , Humanos , Masculino , Grupo Paritario , Instituciones Académicas , Medio SocialRESUMEN
Maternal smoking is associated with a host of negative health outcomes, including an increased risk of children developing attention-deficit/hyperactivity disorder (ADHD). This study evaluated the efficacy of health messages disseminated through Facebook Ads focused on reducing tobacco smoke exposure during pregnancy. Two message versions were promoted via post advertisements on Facebook-a static infographic and a video containing an animated version of the infographic. The reach of and engagement with each message version was evaluated. Comments made to the posts were assessed using content analysis. The infographic reached approximately 60,000 people and the video reached about 16,000 people. The average costs were $10.00 and $40.00 per 1,000 people reached for the infographic- and video-based posts, respectively. While there was no engagement with the video, the infographic was liked (n = 157), given alternative likes (n = 59), shared (n = 171 to 341), and commented on (n = 221). About one-quarter of comments contained a personal narrative and mentions of health history related to ADHD and/or smoking. Comments were more often negative (than positive) (16.6% vs 3.9%) and expressed skepticism more often than message acceptance (21.5% vs 12.2%). Facebook users were more responsive to the infographic (compared to the video) and static posts were a preferred channel (i.e., higher engagement at a lower cost) to disseminate messages when using the boost post feature on Facebook for health education. Our review of the comments provided insights into message acceptance and guidance for future social media-based health message campaigns. However, it is not known whether and if so, how, these findings on message exposure would correlate with behavioral intentions or changes in behavior, such as intentions to quit smoking or smoking cessation.
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Cese del Hábito de Fumar , Medios de Comunicación Sociales , Contaminación por Humo de Tabaco , Niño , Femenino , Humanos , Embarazo , Prevención del Hábito de Fumar , NicotianaRESUMEN
The amygdala and its connections with medial prefrontal cortex (mPFC) play central roles in the development of emotional processes. While several studies have suggested that this circuitry exhibits functional changes across the first two decades of life, findings have been mixed - perhaps resulting from differences in analytic choices across studies. Here we used multiverse analyses to examine the robustness of task-based amygdala-mPFC function findings to analytic choices within the context of an accelerated longitudinal design (4-22 years-old; N = 98; 183 scans; 1-3 scans/participant). Participants recruited from the greater Los Angeles area completed an event-related emotional face (fear, neutral) task. Parallel analyses varying in preprocessing and modeling choices found that age-related change estimates for amygdala reactivity were more robust than task-evoked amygdala-mPFC functional connectivity to varied analytical choices. Specification curves indicated evidence for age-related decreases in amygdala reactivity to faces, though within-participant changes in amygdala reactivity could not be differentiated from between-participant differences. In contrast, amygdala-mPFC functional connectivity results varied across methods much more, and evidence for age-related change in amygdala-mPFC connectivity was not consistent. Generalized psychophysiological interaction (gPPI) measurements of connectivity were especially sensitive to whether a deconvolution step was applied. Our findings demonstrate the importance of assessing the robustness of findings to analysis choices, although the age-related changes in our current work cannot be overinterpreted given low test-retest reliability. Together, these findings highlight both the challenges in estimating developmental change in longitudinal cohorts and the value of multiverse approaches in developmental neuroimaging for assessing robustness of results.
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Amígdala del Cerebelo , Imagen por Resonancia Magnética , Adolescente , Adulto , Amígdala del Cerebelo/fisiología , Niño , Preescolar , Emociones/fisiología , Humanos , Vías Nerviosas/fisiología , Corteza Prefrontal/fisiología , Reproducibilidad de los Resultados , Adulto JovenRESUMEN
Early psychosocial adversities exist at many levels, including caregiving-related, extrafamilial, and sociodemographic, which despite their high interrelatedness may have unique impacts on development. In this paper, we focus on caregiving-related early adversities (crEAs) and parse the heterogeneity of crEAs via data reduction techniques that identify experiential cooccurrences. Using network science, we characterized crEA cooccurrences to represent the comorbidity of crEA experiences across a sample of school-age children (n = 258; 6-12 years old) with a history of crEAs. crEA dimensions (variable level) and crEA subtypes (subject level) were identified using parallel factor analysis/principal component analysis and graph-based Louvain community detection. Bagging enhancement with cross-validation provided estimates of robustness. These data-driven dimensions/subtypes showed evidence of stability, transcended traditional sociolegally defined groups, were more homogenous than sociolegally defined groups, and reduced statistical correlations with sociodemographic factors. Finally, random forests showed both unique and common predictive importance of the crEA dimensions/subtypes for childhood mental health symptoms and academic skills. These data-driven outcomes provide additional tools and recommendations for crEA data reduction to inform precision medicine efforts in this area.
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Trastornos Mentales , Salud Mental , Niño , Humanos , Trastornos Mentales/epidemiología , ComorbilidadRESUMEN
Do children, like most adults, believe that only kin and close others are obligated to help one another? In two studies (total N = 1140), we examined whether children (â¼5- to â¼10-yos) and adults across five different societies consider social relationship when ascribing prosocial obligations. Contrary to the view that such discriminations are a natural default in human reasoning, younger children in the United States (Studies 1 and 2) and across cultures (Study 2) generally judged everyone-parents, friends, and strangers-as obligated to help someone in need. Older children and adults, on the other hand, tended to exhibit more discriminant judgments. They considered parents more obligated to help than friends followed by strangers-although this effect was stronger in some cultures than others. Our findings suggest that children's initial sense of prosocial obligation in social-relational contexts starts out broad and generally becomes more selective over the course of development. (PsycInfo Database Record (c) 2022 APA, all rights reserved).