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2.
Gematol Transfuziol ; 35(9): 33-5, 1990 Sep.
Artículo en Ruso | MEDLINE | ID: mdl-2272454

RESUMEN

It has been shown that low concentrations of potassium chloride change almost similarly the rate constant of oxyhemoglobin autooxidation in tris-buffer and the rate constant of its oxidation by ferricyanide in the same buffer. A conclusion has been made on the principal possibility of using the latter constant as a test for oxyhemoglobin state in solution and, particularly, for its predisposition to autooxidation.


Asunto(s)
Conservación de la Sangre/métodos , Ferricianuros , Hemoglobinas/análisis , Humanos
3.
Izv Akad Nauk SSSR Biol ; (2): 194-201, 1990.
Artículo en Ruso | MEDLINE | ID: mdl-2362035

RESUMEN

The kinetics of human oxyhemoglobin coagulation in neutral phosphate buffer in the presence of mercury acetate at 20 degrees has been studied using turbidimetric methods. The addition of small amounts of concentrated Hg2+ solution leads to rapid local protein coagulation with subsequent dissolution of the formed coagulate. Coagulation can be inhibited by addition of Tris that binds to mercury ions. The pattern of oxyhemoglobin coagulation is determined by molar Hg2+/protein ration rather than by total Hg2+ concentration.


Asunto(s)
Coagulación Sanguínea/efectos de los fármacos , Mercurio/farmacología , Oxihemoglobinas/metabolismo , Fosfatos/farmacología , Tampones (Química) , Relación Dosis-Respuesta a Droga , Humanos , Concentración de Iones de Hidrógeno , Técnicas In Vitro , Nefelometría y Turbidimetría , Yoduro de Potasio/farmacología , Trometamina/farmacología
6.
Antibiotiki ; 28(6): 429-34, 1983 Jun.
Artículo en Ruso | MEDLINE | ID: mdl-6881953

RESUMEN

Sensitivity of 120 staphylococcal strains belonging to different species isolated from newborn infants with pyoseptic infections was studied with respect to 13 antibiotics. Methicillin, cephaloridin, rifampicin, ristomycin, gentamicin and novobiocin were mainly highly active against the isolates, while some of the strains were resistant. The coagulase negative species were as a whole characterized by higher resistance levels with respect to some antibiotics, as compared to Staph. aureus. The predominant part of the coagulase negative strains with exceedingly high resistance levels did not belong to Staph. epidermidis. The sensitivity of staphylococci depended on the source of their isolation. At large the strains isolated from purulent excretions of localized foci were characterized by lower levels of resistance to a number of antibiotics (benzylpenicillin, tetracycline, erythromycin, methicillin and others) as compared to the strains isolated from the blood.


Asunto(s)
Antibacterianos/farmacología , Enfermedades del Recién Nacido/microbiología , Sepsis/microbiología , Infecciones Estafilocócicas/microbiología , Staphylococcus/efectos de los fármacos , Relación Dosis-Respuesta a Droga , Farmacorresistencia Microbiana , Humanos , Recién Nacido , Especificidad de la Especie
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