Urgent Treatment of Complicated Ulcerated Infantile Hemangioma with ß-Blockers via Telemedicine: A Case Report.

Introduction: Infantile hemangiomas (IH) exacerbated by ulceration invariably necessitate hospitalization, although simple IHs are sometimes managed remotely. Furthermore, according to international regulations, ß-blocker medication for such hemangiomas should be systemic and performed in a clinic, especially if there is infection and risk of bleeding. Case: War in Ukraine made it impossible to hospitalize and properly examine a patient with a complex ulcerated and infected IH, forcing us to administer ß-blocker timolol therapy only through telemedicine. Conclusions: Our case demonstrates the possibility of successful distant treatment of IH with ulcer using only a topical ß-blocker carried out remotely through telemedicine, which is critical in the context of the COVID-19 pandemic, war, hostilities, or natural disasters where inpatient treatment is not available.

Pigmented Poroma of the Lower Eyelid: A Case Report and Literature Review.

BACKGROUND Eyelid tumors belong to a diverse group of neoplasms ranging from benign lesions to malignant tumors. Poromas are common, benign, mostly unpigmented tumors of the epidermal sweat duct unit, that usually grow slowly and occur in elderly people on the palms and soles. In most poroma cases some gene fusions were detected, which were caused by chromosomal aberrations. CASE REPORT We report the atypical case of a 30-year-old female patient suffering for more than 15 years from a solitary, polypoid, pigmented formation with a focal tuberous surface on the left lower eyelid. The lesion was not growing during the first years, but in the last 6 months before diagnosis its size more than doubled, finally reaching 12×14 mm. It was removed and histopathological analysis confirmed the diagnosis of a rare tumor - a poroma. There were no complications during healing and no recurrence was reported. CONCLUSIONS There have so far been only 9 reports of eyelid poromas, and the presented case significantly differed from the previous ones, as it appeared at an early age and showed rapid growth during a short time due to the war-related acute psychological stress. Moreover, it had unusual pigmentation and unpleasant smell. Reporting such untypical cases is clinically important because it is crucial to be aware of the diversity of eccrine poroma manifestation to distinguish it from malignant lesions.

Covid-19, leukemia, and secondary malignancies of the skin - is there a connection: a case report and literature analysis.

We report the case of a patient who was diagnosed with two melanomas and one skin cancer within two years. Of particular interest was the fact, that at the time these tumors were diagnosed, the patient was already suffering from chronic myeloid leukemia, which developed three months after recovering from Covid-19. From the time of leukemia occurrence, the patient has been taking the tyrosine kinase inhibitor (TKI) - Gleevec. Thus, we took into the account the possibile effect of Gleevec administration on the risk of skin tumor appearance. It was also important to analyze the impact of the SARS-CoV-2 virus and chronic myeloid leukemia on the risk of secondary malignancies. According to so far published data, the direct relationship between Gleevec treatment and the occurrence of skin cancers cannot be proved. However, literature data indicate a direct and indirect relationship between SARS-CoV-2 infection and an increased incidence of carcinogenesis.

Store-and-forward teledermatology for the most common skin neoplasms in Ukraine.

BACKGROUND: Among all malignancies in Ukraine in 2016, the group of non-melanoma skin cancers headed the list in men and made up 21.6%. This group was second in women and made up 17.6%. The diagnostics of skin tumors are becoming increasingly relevant. METHODS: The store-and-forward (SAF) method was used. The study included patients that were remotely diagnosed with melanocytic nevi, seborrheic keratoses, skin cancer, and skin melanoma. Patients signed up for remote diagnostics, were examined in person by dermatologists, and had tumors excised with a subsequent histological examination. RESULTS: Using telemedicine, 108 melanocytic nevi, 97 seborrheic keratoses, 62 skin cancers, and 47 skin melanomas were diagnosed and selected. The accuracy of teledermatological examination and teledermoscopy compared to clinical examination and dermoscopy was 90.3 to 100.0%. The accuracy of teledermatological examination and teledermoscopy compared to histopathological diagnoses was 85.1 to 98.9%. CONCLUSIONS: Teledermatological diagnosis showed a high ability for detecting skin neoplasms in Ukraine.