[The effect of influenza and para-influenza on the course of ischemic heart disease]. / Vliianie grippa i paragrippa na techenie ishemicheskoi bolezni serdtsa.

A retrospective analysis was made of 541 case reports of patients with coronary heart disease admitted to the infectious department with the diagnosis of influenza (n-387) and parainfluenza (n-154). In all the patients, the diagnosis was verified serologically with the aid of the hemagglutination inhibition test, with a 4-fold and greater increase of the antibody titer in the serum. In part of the patients, it was confirmed by the above test combined with immunofluorescence in examining rhinopharyngeal smears and in part of influenza patients, it was verified virologically. Exacerbation of CHD was seen in the period of early convalescence in 60% of cases whatever the etiology of viral infection (days 5-13 of the disease). As compared to parainfluenza, influenza provoked the deterioration of CHD significantly more often, especially influenza B (25 and 14.3%). The group at risk for an unfavourable outcome of CHD included patients with influenza and parainfluenza, suffering from postinfarction cardiosclerosis. In this group, exacerbation of CHD was diagnosed in 38.3 and 26.1% of cases, whereas acute myocardial infarction developed in 11.7 and 4.4% of cases. Every second influenza patient and every third parainfluenza patient with acute pneumonia and postinfarction cardiosclerosis demonstrated deterioration of CHD.

[The incidence of exacerbations in chronic diseases in patients hospitalized with influenza and para-influenza]. / O chastote obostrenii khronicheskikh zabolevanii u gospitalizirovannykh bol'nykh grippom i paragrippom.

A retrospective analysis was made of the case reports of 829 patients admitted to the infectious department with a diagnosis of influenza (592) and parainfluenza (237). In all the patients, the diagnosis was supported serologically with the aid of the hemagglutination inhibition test, with the antibody titer in the serum rising 4-fold and more. In part of the patients the indicated test was used in combination with the immunofluorescence test in studying nasopharyngeal smears, whereas in part of the patients, it was coupled with virological tests. It has been revealed that in addition to the most frequently occurring complications on the part of the bronchopulmonary system and ENT organs caused by the pneumococcal and streptococcal flora, there were complications on the part of the endocrine, urogenital, nervous and gastrointestinal systems, equally in patients with influenza and parainfluenza. In patients with postinfarction cardiosclerosis, influenza B and mixed influenza run the most unfavourable course, provoking deterioration of coronary heart disease in every other patient. In 66.6% of cases, exacerbation of coronary heart disease fell within the period of early convalescence of patients with influenza and parainfluenza.