RESUMEN
A survey of West Midlands paediatricians in 2001 identified 24 cases of symptomatic vitamin D deficiency in children less than 5 years of age. The overall incidence was 7.5 per 100,000 children per year with notable differences in incidence per ethnic group.
Asunto(s)
Deficiencia de Vitamina D/epidemiología , África/etnología , Asia/etnología , Lactancia Materna/estadística & datos numéricos , Niño , Preescolar , Inglaterra/epidemiología , Femenino , Humanos , Incidencia , Lactante , Recién Nacido , Masculino , Estudios Prospectivos , Indias Occidentales/etnologíaRESUMEN
The rectal "inflammatory cloacogenic polyp" is a recognized pathologic entity in adulthood. We report three cases in children aged between 8 and 12 years. This disorder should be included in the differential diagnosis in patients with hematochezia and tenesmus. These polyps are usually located at the anorectal junction and so may be overlooked at colonoscopy unless an endoscopic retroflexion maneuver is performed.
Asunto(s)
Enfermedades del Ano/etiología , Hemorragia Gastrointestinal/etiología , Pólipos Intestinales/complicaciones , Dolor/etiología , Neoplasias del Recto/complicaciones , Enfermedades del Ano/diagnóstico , Enfermedades del Ano/patología , Biopsia , Niño , Defecación , Femenino , Hemorragia Gastrointestinal/diagnóstico , Hemorragia Gastrointestinal/patología , Humanos , Mucosa Intestinal/patología , Pólipos Intestinales/diagnóstico , Pólipos Intestinales/patología , Masculino , Dolor/diagnóstico , Dolor/patología , Neoplasias del Recto/diagnóstico , Neoplasias del Recto/patología , Recto/patologíaRESUMEN
OBJECTIVE: To describe four infants with protracted diarrhea caused by glucose polymer intolerance resulting from congenital sucrase-isomaltase deficiency. METHODS: The diagnosis of congenital sucrase-isomaltase deficiency was established by mucosal disaccharidase assay. In each case the clinical response to discontinuation of glucose polymer was documented. RESULTS: The median age at the onset of symptoms was 3 weeks (range, 2 to 16 weeks). In three infants the formula had been prescribed for presumed postgastroenteritis diarrhea, and in a fourth it was begun after resection of a short-segment congenital ileal atresia. In each infant watery diarrhea occurred and persisted for many months, and it was assumed that the original gastrointestinal disorder was responsible. In two cases, parenteral nutrition was administered for persistent failure to thrive. Ultimately, investigation revealed the underlying congenital sucrase-isomaltase deficiency, and elimination of glucose polymer from the diet led to immediate recovery in each case. CONCLUSION: Congenital sucrase-isomaltase deficiency should be considered a possible cause of protracted diarrhea in infants receiving glucose polymer-based feedings.