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1.
Parasitology ; : 1-9, 2023 Jan 20.
Artículo en Inglés | MEDLINE | ID: mdl-36661208

RESUMEN

Infection of sheep by gastrointestinal nematodes (GIN) in pastoral systems such as those found in the South Western area of France, the Pyrénées Atlantiques, is one of the main reasons for economic loss and degradation of their welfare. In the present study, the efficacy of eprinomectin (EPN) was monitored on farms from this area following suspicion of lack of anthelmintic efficacy. Suspicions were raised by veterinarians, based on clinical signs ranging from milk and body condition loss, to anaemia, and mortality. Resistance was evaluated according to the World Association for the Advancement for Veterinary Parasitology (WAAVP) guidelines using fecal egg count reduction tests reinforced by individual analysis of drug concentration in the serum of all treated ewes by high-performance liquid chromatography (HPLC). EPN was administered by subcutaneous (SC) and topical (T) route according to manufacturer's requirements, as well as by the oral route (O) with the topical solution according to off-labelled practices in the field. For the first time in France, the presence of resistant isolates of Haemonchus contortus to EPN was observed in 5 dairy sheep farms. The HPLC dosages showed exposure of worms to concentrations compatible with anthelmintic activity for animals treated by the SC and O routes. By contrast, they showed under exposure to the drug of most individuals treated by the T route. EPN is the only null milk withdrawal anthelmintic molecule currently available. The presence of resistant isolates of the pathogenic H. contortus to EPN in this important dairy region requires an urgent change in grazing, and sometimes production, systems.

2.
Sci Rep ; 9(1): 12699, 2019 09 03.
Artículo en Inglés | MEDLINE | ID: mdl-31481719

RESUMEN

Managing infections of sheep with anthelmintic resistant gastrointestinal nematodes (GIN) is a major challenge for sheep producers in Western Europe. New methods of grazing management have been poorly explored as a component of an integrated and sustainable control of these parasites. Therefore, the purpose of this study was to evaluate the effect of two different types of grazing systems of sheep (intensive cell grazing versus conventional rotational grazing) on GIN infections over two years in a farm located in a temperate environment of Western France. When considering the whole study, the type of grazing system did not influence significantly the intensity of egg excretions of adult ewes even if the proportion of ewes excreting high numbers of GIN eggs was higher in cell grazing system than in rotational grazing system. The most striking result of this survey was the effect of grazing system on the GIN species composition harbored by ewes and by their lambs: with time, the proportions of H. contortus infections were lower in cell grazing system than in rotational grazing system. In conclusion, the cell grazing system, as implemented in this study, could limit the importance of this highly pathogenic nematode species in sheep.


Asunto(s)
Antihelmínticos/uso terapéutico , Resistencia a Medicamentos , Enfermedades Gastrointestinales , Hemoncosis , Haemonchus/crecimiento & desarrollo , Estaciones del Año , Enfermedades de las Ovejas , Ovinos/parasitología , Animales , Heces/parasitología , Francia , Enfermedades Gastrointestinales/tratamiento farmacológico , Enfermedades Gastrointestinales/parasitología , Enfermedades Gastrointestinales/veterinaria , Hemoncosis/tratamiento farmacológico , Hemoncosis/parasitología , Hemoncosis/veterinaria , Recuento de Huevos de Parásitos , Enfermedades de las Ovejas/tratamiento farmacológico , Enfermedades de las Ovejas/parasitología
3.
Trauma (Majadahonda) ; 25(1): 18-20, ene.-mar. 2014. ilus
Artículo en Español | IBECS | ID: ibc-122352

RESUMEN

Presentamos una lesión vascular en un varón intervenido mediante discectomía L5-S1, que volvió a consulta al año de la cirugía por una nueva lumbociatalgia con imagen de fibrosis en RMN y se le realizó una artrodesis L5-S1. Durante el tiempo de discectomía y preparación del espacio se identificó sangrado arterial. Ante el deterioro general, se procedió a efectuar una laparotomía media, encontrando un hematoma retroperitoneal y lesión arterial hipogástrica derecha por laceración. La lesión de la aorta o de sus ramas durante la discectomía es más frecuente en reintervenciones, precisando su detección y reparación inmediatas (AU)


We present a case of a male who underwent a right L5/S1 discectomy. He returned to his work after three months. A year after the patient consulted again for sciatic pain and MRI showed mild epidural fibrosis. He underwent a new surgery and during the discectomy step an arterial bleeding was identifacated. Given the general deterioration, the vascular surgeon proceeds to midline laparotomy, aortic clamping, vascular exploration with an important retroperitoneal hematoma and right hypogastric artery injury. Vascular injuries during the time of discectomy are more frequent reported in reoperations. Once this occurs, detection and immediate repair are prior (AU)


Asunto(s)
Humanos , Masculino , Adulto , Enfermedades Vasculares/complicaciones , Enfermedades Vasculares/diagnóstico , Dolor de la Región Lumbar/complicaciones , Dolor de la Región Lumbar , Discectomía/métodos , Discectomía , Artrodesis/instrumentación , Artrodesis/métodos , Reoperación/métodos , Vértebras Lumbares/patología , Vértebras Lumbares/cirugía , Fibrosis/complicaciones , Fibrosis , Imagen por Resonancia Magnética/métodos , Laparotomía/métodos , Laparotomía , Laceraciones/complicaciones , Laceraciones/cirugía , Laceraciones
4.
Acta pediatr. esp ; 69(10): 450-454, nov. 2011. tab, graf
Artículo en Español | IBECS | ID: ibc-99257

RESUMEN

Objetivo: Evaluar la información que los padres buscan sobre la salud de sus hijos. Material y métodos: Estudio descriptivo de la población urbana atendida en un centro de atención primaria por el servicio de pediatría. Durante un periodo de 5 meses, un total de 201 padres que acudían a nuestras consultas rellenaron un cuestionario sobre las fuentes de información que utilizan respecto a la salud de sus hijos. Resultados: El 66% de los padres consulta algún medio de comunicación sobre problemas de salud. Los medios más utilizados son Internet (85%), las revistas especializadas (36%) y la televisión (18%). El 96% de respondedores tiene acceso a la red, y de éstos el 85% tiene conexión en casa. El 67% consultó algún problema médico en Internet durante el último año, y de éstos a un 93% le resultó útil. El 84% de los padres que habían consultado Internet en el último año se informaron por este medio de algún problema de salud antes y/o después de visitar a su pediatra/enfermera. Un 45% de los padres se alarmó después de leer alguna información médica en algún medio de comunicación, y un 65% de éstos consultó a su pediatra o enfermera por este motivo. Un 98% confía más en su pediatra que en Internet. Conclusión: Una elevada proporción de padres tiene acceso a Internet y lo utiliza para obtener información sobre temas de salud de sus hijos. Frecuentemente, esta búsqueda está relacionada con las visitas realizadas al personal sanitario. Los profesionales de la salud deberíamos estar preparados para orientar a los padres en la búsqueda de información en la Red(AU)


Objective: To evaluate the information that parents are looking for about their children’s health. Material and methods: Descriptive study of the urban population attended at a primary care center by the pediatric services. During a 5-month period, a total of 201 parents came to our consultations and filled out a questionnaire about the information sources that they use regarding their children’s health. Results: 66% of the parents consulted some kind of mass media about health issues. The most widely used are Internet (85%), specialized magazines (36%) and television (18%). 96%of respondents have access to the internet; of these 85% have access at their home. 67% consulted for a medical problem on the Internet during the last year, 93% of these found it helpful. 84% of the parents who had accessed Internet got information through this source about any kind of health problem before and or after visiting the pediatrician or nurse. 45% of the parents were alarmed after reading some medical information in mass media and 65% of these, consulted their doctor or nurse about it. A 98% have more confidence in their pediatrician tha non the Internet. Conclusion: A high percentage of parents have Internet access and uses it to obtain information on health issues about their children. This search is often related to visits by health professionals. Health professionals should be prepared on guiding parents to find information on the Internet(AU)


Asunto(s)
Humanos , Internet , Información de Salud al Consumidor , Centros de Información/provisión & distribución , Indicadores de Sociedad de la Información , Acceso a la Información , Alfabetización Informacional , Atención Primaria de Salud/tendencias
5.
Foot Ankle Surg ; 16(3): 132-6, 2010 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-20655013

RESUMEN

BACKGROUND: Opening wedge proximal metatarsal osteotomy combined with first metatarsophalangeal arthroplasty can be used to correct first metatarsus primus varus with a high intermetatarsal angle and a short first metatarsal. METHODS: 147 feet in 138 patients with degenerative first metatarsophalangeal arthrosis, >or=15 degrees of metatarsus primus varus and, a short first metatarsal were included. Preoperative and postoperative clinical, radiographic, and subjective outcome measurements were taken (Scale AOFAS). RESULTS: The mean first intermetatarsal angle decrease was 7.79+/-1.43 degrees and the mean increase in first metatarsal length was 2.88+/-0.45 mm. The pre-intervention mean values were 52.6 points in the AOFAS scale, and an overall result of 92.95 obtained after surgery (P<0.001). CONCLUSIONS: The opening proximal first metatarsal osteotomy without internal fixation and with first metatarsophalangeal resection arthroplasty can correct severe hallux valgus with an intermetatarsal angle >or=15 degrees and a short first metatarsal, achieving low rate of complications.


Asunto(s)
Artroplastia/métodos , Hallux Valgus/cirugía , Articulación Metatarsofalángica/cirugía , Osteotomía/métodos , Adulto , Anciano , Anciano de 80 o más Años , Femenino , Estudios de Seguimiento , Hallux Valgus/diagnóstico por imagen , Hallux Valgus/fisiopatología , Humanos , Masculino , Articulación Metatarsofalángica/diagnóstico por imagen , Articulación Metatarsofalángica/fisiopatología , Persona de Mediana Edad , Satisfacción del Paciente , Radiografía , Rango del Movimiento Articular , Estudios Retrospectivos , Índice de Severidad de la Enfermedad , Factores de Tiempo , Resultado del Tratamiento
6.
Foot Ankle Surg ; 16(2): 65-9, 2010 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-20483136

RESUMEN

OBJECTIVE: The purpose of proximal tarso-metatarsal joint resection is to provide early weight-loading for biomechanical realignment and correct weight imbalance across the MTP joint. Therefore, its main indications are all those metatarsalgia in which previous orthopaedic treatment has failed. MATERIAL AND METHODS: We report our experience in metatarsalgia management with proximal metatarsal resection. This is a retrospective study between April 1997 and December 2005. 40 feet underwent this procedure (36 patients), with a total report of 86 osteotomies. Clinical results were evaluated with American Orthopaedic Foot and Ankle Society Lesser Metatarsophalangeal-Interphalangeal Scale Score (maximum score: 100 points). RESULTS: A 10-15-grade correction was achieved with a mean resection of 2mm. Assessment with AOFAS' scale disclosed previous average 35.75+/-4.2 with a final score reported of 88.4+/-6.9 (range 65-100). An overall mean increase of 52.65 points was achieved. No case had major complications that required further surgery. Pain improved in 39 patients (97.5%), and persisted in one patient. CONCLUSIONS: Proximal metatarsal resection is a simple technique that provides adequate correction of the abnormal pressure distribution across the MTP joint without internal fixation.


Asunto(s)
Huesos Metatarsianos/cirugía , Metatarsalgia/cirugía , Procedimientos Ortopédicos/métodos , Adulto , Anciano , Anciano de 80 o más Años , Femenino , Humanos , Persona de Mediana Edad , Dimensión del Dolor , Estudios Retrospectivos , Resultado del Tratamiento
7.
Rev. esp. cir. ortop. traumatol. (Ed. impr.) ; 54(1): 73-76, ene.-feb. 2010. ilus
Artículo en Español | IBECS | ID: ibc-76459

RESUMEN

Objetivos: A propósito de un caso de seudoartrosis de hueso grande, nos proponemos revisar la bibliografía sobre el tratamiento de este tipo de fracturas y de su seudoartrosis. Material y métodos: Presentamos el caso de una fractura de hueso grande desapercibida tras traumatismo en hiperextensión, que originó una seudoartrosis posterior. Resultados: Tras intervenirse quirúrgicamente mediante osteosíntesis con tornillo de Herbert-Whipple, previa cruentación del foco, se logró una curación satisfactoria. Conclusiones: La seudoartrosis de hueso grande es una causa infrecuente de dolor oculto en la muñeca. La historia clínica del dolor, la tumefacción sobre el arco carpiano distal, en ocasiones las imágenes radiográficas y, especialmente, los estudios complementarios con TAC o RMN deben confirmar el diagnóstico (AU)


Purpose: The purpose of the study is to review the literature on the treatment of capitate bone fracture and pseudoarthrosis. Materials and methods: We present the case of a capitate bone fracture that went undetected following trauma caused by forced hyperextension leading to posterior pseudoarthrosis. Results: A satisfactory result was achieved by surgery with Herbert-Whipple screw fixation preceded by fracture site refreshment. Conclusions: Hamate bone pseudoarthrosis is a rare cause of occult pain in the wrist. The pain's clinical history, numbness of the distal carpal arch, some radiographic findings and, especially, complementary CT- or MRi studies are elements that must be used to confirm an initial diagnosis (AU)


Asunto(s)
Humanos , Masculino , Adolescente , Seudoartrosis/complicaciones , Seudoartrosis/diagnóstico , Traumatismos de la Mano/diagnóstico , Traumatismos de la Mano/terapia , Seudoartrosis , Huesos de la Extremidad Superior/lesiones , Huesos de la Extremidad Superior/patología , Huesos/lesiones , Traumatismos de la Mano/fisiopatología , Traumatismos de la Mano
8.
J Hand Surg Eur Vol ; 35(3): 195-7, 2010 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-20007423

RESUMEN

Between 1997 and 2006, radiographs of 66 scaphoid fractures were retrospectively reviewed to evaluate ulnar variance. Twenty-one (31.8%) patients had an 'ulna neutral' wrist, six (9.1%) had an 'ulna plus' and 39 (59.1%) had an 'ulna minus' wrist. The mean ulnar variance was -1.3 (SD 1.8) mm (range -5.5, 2.5). We observed a significant difference in the distribution of ulnar variance (P < 0.00001) and in the proportion of cases with ulna minus (OR = 5.0; 95% CI: 2.7, 9.3) compared to previous publications.


Asunto(s)
Fracturas Óseas/patología , Hueso Escafoides/lesiones , Cúbito/patología , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Femenino , Fracturas Óseas/diagnóstico por imagen , Humanos , Masculino , Persona de Mediana Edad , Radiografía , Estudios Retrospectivos , Hueso Escafoides/diagnóstico por imagen , Cúbito/fisiopatología , Adulto Joven
10.
Ann Otolaryngol Chir Cervicofac ; 107 Suppl 1: 51-6, 1990.
Artículo en Francés | MEDLINE | ID: mdl-2240999

RESUMEN

This study was conducted in order to assess the activity of trimetazidine dosed at 60 mg/day in patients presenting degenerative loss of hearing. Ten centers participated in this multicenter double-blind placebo-controlled trial which spanned 6 months. Included were 251 patients (118 women, 133 men) presenting with pure perception bilateral symmetrical deafness concerning predominantly the acute frequency range. 228 patients terminated the study, including 115 in the trimetazidine group and 113 in the placebo group. The evolution over a 6-month treatment period was significantly better with trimetazidine as regards the following parameters: audibility as assessed by pure-tone audiometry, namely at the acute frequency range (p = 0.002), intelligibility as assessed by speech audiometry (p = 0.008), subjective evaluation of hearing loss and its impact on the patient's social life. Results confirm the value of trimetazidine hearing loss management, based on clinical, subjective criteria as well as audiometric ones. Parameters reflecting best trimetazidine's efficacy were intelligibility and the psychological/behavioral impact of the impairment, allowing for better social integration of the subject.


Asunto(s)
Pérdida Auditiva/tratamiento farmacológico , Audición/efectos de los fármacos , Trimetazidina/uso terapéutico , Anciano , Anciano de 80 o más Años , Audiometría , Método Doble Ciego , Femenino , Humanos , Masculino , Persona de Mediana Edad , Placebos , Distribución Aleatoria , Percepción del Habla/efectos de los fármacos , Factores de Tiempo
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