[SHF-thermography in allergic diseases]. / SVCh-termografiia pri allergicheskikh zabolevaniiakh.

The results of combined clinical allergologic study and SHF thermography in patients with pollenosis, chronic asthmatic bronchitis, bronchial asthma, continuous and seasonal allergic rhinitis and normal controls are reported. Patients with pulmonary disorders showed a reduction by 1 degree C in mean deep temperature around the lungs, and a sevenfold increase in deep temperature dispersion, as compared to the controls. Patients with pollenosis showed a reduction of deep temperatures by 1.5-2 degrees C in the gastric area and the ascending intestinal portion. In patients with allergic rhinitis, the temperature differences between the tip of the nose and maxillary sinuses, typical for normal subjects, become insignificant. Possible mechanisms of the demonstrated temperature abnormalities are discussed. The data obtained are compared to those obtained by means of IR thermography in the same categories of patients.

[New method of diagnosis of drug hypersensitivity of the delayed type--the scarificaiton-film test]. / Novyi metod diagnostiki lekarstvennoi allergii zamedlennogo tipa--skarifikatsionno-plenochnyi test

An original method for diagnosis of drug allergy, i.e. a scarification-film test (SFT) in 2 variants has been worked out for the first itme on the basis of examination of 241 persons and is recommended for use. 10 mm parallel scarifications with intervals of 3-4 mm between them were made on the epidermis of the antibrachial flexor and the following agents were applied to them: 1) a film-forming aerosol composition with medicines (tetracycline)--the 1st variant of SFT. (2) powder or solutions of medicines (antibiotics, sulfanylamides, vitamins, etc.) covered with a film-forming ocmposition without any medicine--the 2nd variant of SFT, 3) film-forming aerosol composition without any medicine-control of both variants out of 46 patients with professional dermatosis and in 10 (7.8 per cent) out of 127 practically healthy persons with latent sensitization (workers of pharmaceutical factories) being in contact with tetracycline. Hypersensitivity of the delay type to benzylpenicillin, streptomycin, sulfanylamides and other medicines was found in 54 79.4 per cent) out of 68 patients with drug allergy of professional and non-professional etiology. The method was shown to be highly sensitive, handy, simple and safe, which provided its recommendation for the use in wide clinical practice for diagnosis of drug allergy of the retarded type which developed because of drug use or professional contact.

[Possibility of the intrauterine sensitization to benzylpenicillin and ampicillin in Syrian hamsters]. / O vozmozhnosti vnutritrobnoi sensibilizatsii k benzilpenitsillinu i ampitsillinu u siriiskikh khomiakov

Immunization of Syrian female hamsters with benzylpenicillin and ampicillin resulted in positive skin reactions of the retarded type and decreased titers of the blood antihistamine factor (AHF) in a part of the posterity. Penicillin allergy was in particular observed in the posterity of the female hamsters immunited before the pregnancy. The state of allergy to penicillins was found in the posterity of the female hamsters with both the positive and negative skin reactions on immunization during the 2nd half of the pregnancy.