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Safety and efficacy of trastuzumab emtansine (TDM-1) in a patient on hemodialysis for renal failure.
Cancer Treat Res Commun
; 27: 100314, 2021.
Artículo
en Inglés
| MEDLINE
| ID: mdl-33545569
RESUMEN
HER2-positive metastatic breast cancer is an aggressive disease with a limited number of treatment options. In the last 15 years, new drugs such as trastuzumab, pertuzumab, lapatinib or trastuzumab emtansine (TDM-1) have sprouted for these patients. There is a huge lack of evidence on the use of some of these drugs in patients with chronic renal failure, who need hemodialysis. We have reviewed the use of TDM-1 in these type of patients in the literature with unsuccessful results. In this article we want to present a case report to illustrate the safety and efficacy of TDM-1 in a patient on hemodialysis.