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Toxins (Basel) ; 13(11)2021 11 22.
Artículo en Inglés | MEDLINE | ID: mdl-34822612

RESUMEN

Spastic equinovarus (SEV) foot deformity is commonly observed in patients with post-stroke spasticity. Tibialis posterior (TP) is a common target for botulinum toxin type-A (BoNT-A) injection, as a first-line treatment in non-fixed SEV deformity. For this deep muscle, ultrasonographic guidance is crucial to achieving maximum accuracy for the BoNT-A injection. In current clinical practice, there are three approaches to target the TP: an anterior, a posteromedial, and a posterior. To date, previous studies have failed to identify the best approach for needle insertion into TP. To explore the ultrasonographic characteristics of these approaches, we investigated affected and unaffected legs of 25 stroke patients with SEV treated with BoNT-A. We evaluated the qualitative (echo intensity) and quantitative (muscle depth, muscle thickness, overlying muscle, subcutaneous tissue, cross-sectional area) ultrasound characteristics of the three approaches for TP injection. In our sample, we observed significant differences among almost all the parameters of the three approaches, except for the safety window. Moreover, our analysis showed significant differences in cross-sectional area between treated and untreated. Advantages and disadvantages of each approach were investigated. Our findings can thus provide a suitable reference for clinical settings, especially for novice operators.


Asunto(s)
Toxinas Botulínicas Tipo A/administración & dosificación , Pie Equinovaro/tratamiento farmacológico , Fármacos Neuromusculares/administración & dosificación , Accidente Cerebrovascular/complicaciones , Anciano , Pie Equinovaro/etiología , Femenino , Humanos , Masculino , Persona de Mediana Edad , Espasticidad Muscular/tratamiento farmacológico , Espasticidad Muscular/etiología , Músculo Esquelético/diagnóstico por imagen , Músculo Esquelético/efectos de los fármacos , Ultrasonografía
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