1.
In Vitro Cell Dev Biol Anim
; 46(3-4): 173-7, 2010 Apr.
Artículo
en Inglés
| MEDLINE
| ID: mdl-20333479
RESUMEN
OxF1 is a human embryonic stem cell line derived from a surplus embryo donated through the Oxford IVF clinic. The cells have a stable 46 XX karyotype and show expression of Oct 4, Nanog and TRA-1-60. Embryoid bodies differentiate into cells that represent all three germ layers as demonstrated by immunohistochemical localisation of beta III tubulin, nestin, desmin, smooth muscle actin, Gata 6 and cytokeratin 18. Directed differentiation through haematopoiesis has been demonstrated.