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Evaluation of erythrocyte shape and status by laser interference microscopy.

Yusipovich, A I; Bryzgalova, N Y; Parshina, E Y; Lomakin, A G; Rodnenkov, O V; Levin, G G; Maksimov, G V; Rubin, A B.

Bull Exp Biol Med ; 145(3): 382-5, 2008 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-19039950

RESUMEN

The area, thickness, and volume of erythrocytes of different types (discocytes, stomatocytes, and echinocytes) from normal subjects and coronary patients were studied by laser interference microscopy. Increase of pH value leading to the stomatocyte-discocyte-echinocyte transformations resulted in a slight decrease of cell volume. In coronary patients, erythrocyte had larger area and volume and exhibited increased aggregation capacity compared to erythrocytes from controls. The results recommend laser interference microscopy as an adequate method for erythrocyte evaluation in laboratory diagnostic measurements.

Asunto(s)

Índices de Eritrocitos , Eritrocitos/citología , Donantes de Sangre , Enfermedad Coronaria/sangre , Humanos , Microscopía Confocal , Microscopía de Interferencia

Modifying effect of nitric oxide on rat blood plasma proteins and hemoglobin.

Akhalaia, M I; Baizhumanov, A A; Brazhe, N A; Luneva, O G; Mikhailov, I V; Bryzgalova, N Y; Parshina, E Y; Maksimov, G V; Rubin, A B.

Dokl Biochem Biophys ; 415: 222-4, 2007.

Artículo en Inglés | MEDLINE | ID: mdl-17933340

Asunto(s)

Proteínas Sanguíneas/metabolismo , Membrana Eritrocítica/efectos de los fármacos , Hemoglobinas/metabolismo , Óxido Nítrico/farmacología , Nitroprusiato/farmacología , Plasma/efectos de los fármacos , Vasodilatadores/farmacología , Animales , Viscosidad Sanguínea , Membrana Eritrocítica/metabolismo , Oxígeno/química , Oxígeno/metabolismo , Plasma/metabolismo , Unión Proteica , Ratas

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