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2.
Rheumatology (Oxford) ; 57(6): 951-958, 2018 Jun 01.
Artículo en Inglés | MEDLINE | ID: mdl-28968896

RESUMEN

Gout is the most common cause of inflammatory arthritis worldwide, and reports show that despite availability of therapies, management is still suboptimal. The new EULAR 2016 recommendations for the treatment of gout highlight the huge development in gout therapies, and the number of drugs being trialled only continues to increase. A clinical review of the evidence that underlies the recommendations from EULAR can reveal possible gaps in the literature and avenues for future research into gout therapies.


Asunto(s)
Manejo de la Enfermedad , Medicina Basada en la Evidencia/métodos , Supresores de la Gota/uso terapéutico , Gota/tratamiento farmacológico , Humanos
3.
Rheumatology (Oxford) ; 55(5): 775-9, 2016 May.
Artículo en Inglés | MEDLINE | ID: mdl-26424838

RESUMEN

With the explosion in biologics use in rheumatology, newer and smarter ways of using these drugs in different diseases have been advocated. SLE has to date been at the back of the biologics algorithms. Recently, the US Food and Drug Administration and European Medicines Evaluation Agency licensed belimumab for use in SLE, the first drug in >30 years. A clinical review of the evidence that underlies the use of belimumab and other biologics in SLE reveals possible reasons why the results are not as spectacular as they are in other diseases.


Asunto(s)
Productos Biológicos/uso terapéutico , Lupus Eritematoso Sistémico/tratamiento farmacológico , Anticuerpos Monoclonales Humanizados/uso terapéutico , Medicina Basada en la Evidencia/métodos , Humanos , Inmunosupresores/uso terapéutico , Selección de Paciente
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