The social sciences needs more than integrative experimental designs: We need better theories.

Almaatouq et al.'s prescription for more integrative experimental designs is welcome but does not address an equally important problem: Lack of adequate theories. We highlight two features theories ought to satisfy: "Well-specified" and "grounded." We discuss the importance of these features, some positive exemplars, and the complementarity between the target article's prescriptions and improved theorizing.

Intranasal Oxytocin Modulates Decision-Making Depending on Outcome Predictability-A Randomized Within-Subject Controlled Trial in Healthy Males.

Oxytocin (OT) has been extensively studied with regard to its socio-cognitive and -behavioral effects. Its potential as a therapeutic agent is being discussed for a range of neuropsychiatric conditions. However, there is limited evidence of its effects on non-social cognition in general and decision-making in particular, despite the importance of these functions in neuropsychiatry. Using a crossover/within-subject, blinded, randomized design, we investigated for the first time if intranasal OT (24 IU) affects decision-making differently depending on outcome predictability/ambiguity in healthy males. The Iowa Gambling Task (IGT) and the Cambridge Risk Task (CRT) were used to assess decision-making under low outcome predictability/high ambiguity and under high outcome probability/low ambiguity, respectively. After administration of OT, subjects performed worse and exhibited riskier performance in the IGT (low outcome predictability/high ambiguity), whereas they made borderline-significant less risky decisions in the CRT (high outcome probability/low ambiguity) as compared to the control condition. Decision-making in healthy males may therefore be influenced by OT and adjusted as a function of contextual information, with implications for clinical trials investigating OT in neuropsychiatric conditions.

Divergent effects of oxytocin on "mind-reading" in healthy males.

The neuropeptide oxytocin (OT) has been associated with a broad range of human behaviors, particularly in the domain of social cognition, and is being discussed to play a role in a range of psychiatric disorders. Studies using the Reading The Mind In The Eyes Test (RMET) to investigate the role of OT in mental state recognition reported inconsistent outcomes. The present study applied a randomized, double-blind, cross-over design, and included measures of serum OT. Twenty healthy males received intranasal placebo or OT (24 IU) before performing the RMET. Frequentist and Bayesian analyses showed that contrary to previous studies (Domes et al., 2007; Radke & de Bruijn, 2015), individuals performed worse in the OT condition compared to the placebo condition (p = 0.023, Cohen's d = 0.55, 95% confidence interval [CI] [0.08, 1.02], BF10 = 6.93). OT effects did not depend on item characteristics (difficulty, valence, intensity, sex) of the RMET. Furthermore, OT serum levels did not change after intranasal OT administration. Given that similar study designs lead to heterogeneous outcomes, our results highlight the complexity of OT effects and support evidence that OT might even interfere with social cognitive abilities. However, the Bayesian analysis approach shows that there is only moderate evidence that OT influences mind-reading, highlighting the need for larger-scale studies considering the discussed aspects that might have led to divergent study results.

An evolutionary explanation for ineffective altruism.

We donate billions to charities each year, yet much of our giving is ineffective. Why are we motivated to give but not to give effectively? Building on evolutionary game theory, we argue that donors evolved (genetically or culturally) to be insensitive to efficacy because people tend not to reward efficacy, as social rewards tend to depend on well-defined and highly observable behaviours. We present five experiments testing key predictions of this account that are difficult to reconcile with alternative accounts based on cognitive or emotional limitations. Namely, we show that donors are more sensitive to efficacy when helping (1) themselves or (2) their families. Moreover, (3) social rewarders don't condition on efficacy or other difficult-to-observe behaviours (4, 5), such as the amount donated.

Wanting without enjoying: The social value of sharing experiences.

Social connection can be a rich source of happiness. Humans routinely go out of their way to seek out social connection and avoid social isolation. What are the proximal forces that motivate people to share experiences with others? Here we used a novel experience-sharing and decision-making paradigm to understand the value of shared experiences. In seven experiments across Studies 1 and 2, participants demonstrated a strong motivation to engage in shared experiences. At the same time, participants did not report a commensurate increase in hedonic value or emotional amplification, suggesting that the motivation to share experiences need not derive from their immediate hedonic value. In Study 3, participants reported their explicit beliefs about the reasons people engage in shared experiences: Participants reported being motivated by the desire to forge a social connection. Together, these findings suggest that the desire to share an experience may be distinct from the subjective experience of achieving that state. People may be so driven to connect with each other that social experiences remain valuable even in the most minimalistic contexts.

Becoming stranger: When future selves join the out-group.

One of the most powerful rules of interpersonal behavior is that people are kinder to members of their in-groups than to members of their out-groups. Are people also kinder to their future selves when they expect them to remain members of their current in-groups rather than become members of their current out-groups? In 2 studies, participants in an emotionally charged debate expected either to remain on the same team or to join the opposing team when they returned the following week. Those who expected to join the opposing team were less willing to sacrifice for their future selves, leaving more of an unpleasant task for their future selves to finish and treating their future selves as unkindly as they treated a stranger. These results suggest that the rules that govern interpersonal behavior may also govern intertemporal behavior, and suggest new strategies to encourage prudent decisions. (PsycINFO Database Record

Caught red-minded: Evidence-induced denial of mental transgressions.

We suggest that when confronted with evidence of their socially inappropriate thoughts and feelings, people are sometimes less likely-and not more likely-to acknowledge them because evidence can elicit psychological responses that inhibit candid self-reflection. In 3 studies, participants were induced to exhibit racial bias (Study 1) or to experience inappropriate sexual arousal (Studies 2 and 3). Some participants were then told that the researcher had collected physiological evidence of these mental transgressions. Results showed that participants who were told about the evidence were less willing to acknowledge their mental transgressions, but only if they were told before they had an opportunity to engage in self-reflection. These results suggest that under some circumstances, confronting people with public evidence of their private shortcomings can be counterproductive. (PsycINFO Database Record