RESUMEN
PURPOSE: We aimed to compare the visual outcomes after pars plana vitrectomy (PPV) versus tap and inject (T&I) in fungal endophthalmitis (FE) reported in the literature and to compare the findings from the literature with data from a reference centre. METHODS: We performed a systematic review and meta-analysis of studies reporting the use of PPV versus T&I in FE. We also performed a retrospective review of the clinical records of patients with endophthalmitis from a reference centre in Colombia. RESULTS: We included 13 studies with 334 eyes; 53.59% received PPV and 46.4% received T&I. The overall relative risk of improving ≥ 2 lines in PPV versus T&I was 0.98 (95% confidence interval [CI] 0.80-1.22; p = 0.88) with a mean difference of final visual acuity of 0.26 (95% CI 0.12-0.63; p = 0.18). There were no significant differences in subgroup analysis. Data from the reference centre included 32 endophthalmitis cases, 15.6% of which had a fungal aetiology (80% received PPV and 20% T&I). There were no significant differences in the subgroup analysis. CONCLUSIONS: Based on the findings from the literature and the reference centre, T&I is noninferior to PPV. This is the first meta-analysis in the literature evaluating these effects in FE. It is necessary to execute new prospective randomised controlled studies in patients with endophthalmitis.
RESUMEN
Presentamos el caso de un paciente con ciclodiálisis postraumática difícil de localizar, incluso con ultrabiomicroscopia (UMB) repetida. El objetivo es informar del diagnóstico de una ciclodiálisis pequeña de difícil visualización y con presentación atípica. Paciente con ciclodiálisis postraumática crónica de 1 hora de reloj, con visualización difícil tanto por examen clínico como por imagen (UBM), a pesar de las evaluaciones repetidas. Inicialmente se realizó el tratamiento médico, sin embargo, no se logró el cierre espontáneo y ni la localización exacta. El seguimiento riguroso basado en la sospecha clínica permitió finalmente su ubicación y reparación quirúrgica exitosa. La ciclodiálisis es una condición rara y la mayoría de los oftalmólogos tratan solo unos pocos casos, no existe un protocolo estandarizado y tanto el diagnóstico como el manejo pueden ser difíciles. La gonioscopia sigue siendo el método diagnóstico de elección, y ciertas ayudas de diagnóstico como la UBM y posiblemente la tomografía de coherencia óptica pueden mejorar la sensibilidad de detección, aunque en algunos casos solo la sospecha clínica y el monitoreo riguroso pueden conducir a un diagnóstico preciso y un tratamiento adecuado.
We present the case of a patient with post-traumatic cyclodialysis difficult to locate, even with repetitive ultrabiomicroscopy (BMU). Our objective is to inform the diagnosis of a small cyclodialysis that is difficult to visualize and with an atypical presentation. Patient with chronic post-traumatic cyclodialysis of 1 clock hour, with difficult visualization by both clinical examination and imaging (UBM), despite repeated evaluations. Medical management was undertaken initially, however, no spontaneous closure and no exact localization were achieved. Rigorous follow up based on clinical suspicion allowed finally for its location and successful surgical repair. Cyclodialysis is a rare condition, and most ophthalmologists treat only a few cases, there is no standardized protocol and both diagnosis and management can be difficult. Gonioscopy remains the diagnostic method of choice, and certain diagnostic aids such as UBM and possibly optical coherence tomography (OCT) can improve detection sensitivity, although in some cases only clinical suspicion and rigorous monitoring can lead to accurate diagnosis and proper treatment
