RESUMEN
We report a case of intracranial primitive epidermoid carcinoma localized in the right temporal fossa in a 40-year-old man. The patient was submitted to surgical removal of his tumor and radiotherapy. Unfortunately, the survival time was six weeks after the operation. Clinical, radiological, anatomopathological features and the interest of the radiotherapy are discussed.
Asunto(s)
Neoplasias Encefálicas/terapia , Carcinoma de Células Escamosas/terapia , Adulto , Neoplasias Encefálicas/radioterapia , Neoplasias Encefálicas/cirugía , Carcinoma de Células Escamosas/radioterapia , Carcinoma de Células Escamosas/cirugía , Terapia Combinada , Resultado Fatal , Humanos , Imagen por Resonancia Magnética , Masculino , Procedimientos Neuroquirúrgicos , Tomografía Computarizada por Rayos XRESUMEN
The authors report three cases of cervical degenerative cysts causing medullary or radiculomedullary compression. Anatomicopathological examination confirmed the fibrous nature of the cyst wall and the absence of a synovial layer. One of the cysts was embedded in the ligamentum flavum, whereas the other two were most lateral and adherent to the facet joint. The physiopathogenesis of these cysts is discussed.
Asunto(s)
Vértebras Cervicales/cirugía , Quistes/cirugía , Ligamento Amarillo/cirugía , Síndromes de Compresión Nerviosa/cirugía , Compresión de la Médula Espinal/cirugía , Enfermedades de la Columna Vertebral/cirugía , Raíces Nerviosas Espinales/cirugía , Anciano , Vértebras Cervicales/patología , Quistes/diagnóstico , Quistes/patología , Diagnóstico Diferencial , Femenino , Humanos , Laminectomía , Ligamento Amarillo/patología , Imagen por Resonancia Magnética , Masculino , Síndromes de Compresión Nerviosa/diagnóstico , Síndromes de Compresión Nerviosa/patología , Examen Neurológico , Compresión de la Médula Espinal/diagnóstico , Compresión de la Médula Espinal/patología , Enfermedades de la Columna Vertebral/diagnóstico , Enfermedades de la Columna Vertebral/patología , Raíces Nerviosas Espinales/patologíaRESUMEN
We described a patient with a POEMS syndrome (Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal grammapathy and Skin changes) who was found to have renal involvement with peculiar renal pathological findings. Hitherto, 17 other cases, most of them from Japan, of POEMS syndrome with renal involvement, have been published. Clinical features are variable: acute renal failure with anasarca or moderate chronic renal insufficiency with mild proteinuria. This latter presentation often passes unnoticed. There is no severe HTA, no microangiopathic hemolytic anemia. Renal biopsy shows prominent glomerular changes which are unusual and distinct from membranoproliferative glomerulonephritis (MPGN) and from glomerular thrombotic microangiopathy (TMA). Mesangial proliferation and thickening of the capillary wall with double contour evoke by light microscopy a MPGN. By immunofluorescent microscopy, no immunoglobulins or complement deposits are found. The finding of mesangiolytic lesions has led to the term of "mesangiolytic glomerulonephritis". The presence, on electron microscopy, of lucent subendothelial space could evoke TMA. But there is neither thrombi, nor arteriolar changes. We are inclined to presume that microangiopathic lesions are due to chronic injury of glomerular endothelial cells, exacerbated at outbreaks of the disease. An increased production of IL-6 could support the efficacity of corticosteroid therapy, particularly in acute clinical situations.