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1.
Mem Inst Oswaldo Cruz ; 115: e190338, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-32130368

RESUMEN

Oropouche virus (OROV) is an arthropod-borne virus of the Peribunyaviridae family, transmitted to humans primarily by Culicoides paraensis. It is one of the main arboviruses infecting humans in Brazil, primarily in the Amazon Region. Here, we report the detection of OROV in the saliva and urine of a patient whose samples were collected five days after the onset of symptoms. Nucleotide sequencing and phylogenetic analysis further confirmed the results. To our knowledge, this is the first study reporting the detection of OROV in the saliva and urine of an infected patient. In addition, the results of our study expand the current knowledge pertaining to the natural history of Oropouche fever.


Asunto(s)
Infecciones por Bunyaviridae/diagnóstico , Orthobunyavirus/genética , Orthobunyavirus/aislamiento & purificación , Saliva/virología , Orina/virología , Secuencia de Aminoácidos , Secuencia de Bases , Femenino , Humanos , Persona de Mediana Edad , Filogenia , ARN Viral/genética , Reacción en Cadena de la Polimerasa de Transcriptasa Inversa
2.
Mem. Inst. Oswaldo Cruz ; 115: e190338, 2020. tab, graf
Artículo en Inglés | LILACS | ID: biblio-1091240

RESUMEN

Oropouche virus (OROV) is an arthropod-borne virus of the Peribunyaviridae family, transmitted to humans primarily by Culicoides paraensis. It is one of the main arboviruses infecting humans in Brazil, primarily in the Amazon Region. Here, we report the detection of OROV in the saliva and urine of a patient whose samples were collected five days after the onset of symptoms. Nucleotide sequencing and phylogenetic analysis further confirmed the results. To our knowledge, this is the first study reporting the detection of OROV in the saliva and urine of an infected patient. In addition, the results of our study expand the current knowledge pertaining to the natural history of Oropouche fever.


Asunto(s)
Humanos , Femenino , Saliva/virología , Orina/virología , Orthobunyavirus/aislamiento & purificación , Orthobunyavirus/genética , Infecciones por Bunyaviridae/diagnóstico , Filogenia , ARN Viral/genética , Secuencia de Bases , Secuencia de Aminoácidos , Reacción en Cadena de la Polimerasa de Transcriptasa Inversa , Persona de Mediana Edad
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