Nephrogenic systemic fibrosis in a patient with a p-ANCA systemic vasculitis.

Nephrogenic systemic fibrosis (NSF) is a fibrosing skin condition of unknown origin. Most cases have been described in patients with acute or chronic renal failure. The cutaneous changes include firm and thickened, indurate skin plaques and papules on the extremities and trunk. Histopathology typically shows an increase in dermal fibroblast-like cells associated with mucin deposition. Previous exposition to gadolinium-based contrast agents was closely associated with its onset. We described a patient with the clinical and pathologic picture of NSF presented after an acute renal failure in the course of a perinuclear antineutrophil cytoplasmic antibodies associated systemic vasculitis.

[Septic arthritis due to meningococcus. Report an atypical case presentation]. / Artritis séptica por meningococo. Comunicación de un caso de presentación atípica.

We have observed the case of a 73-years-old man with a septic monoarthritis affecting the left knee due to Neisseria meningitidis serogroup B, without previous traumatism, fever, headache or meningeal symptoms. The patient didnt present risk factors of meningococcal infection. The infection was resolved satisfactorily with parenteral ceftriaxone during 2 weeks and oral ciprofloxacin during 1 month.