Castleman's disease. A rare cause of isolated retroperitoneal mass.

OBJECTIVES: We describe a case of hyaline vascular type Castleman 's disease with unifocal presentation as retroperitoneal mass. We describe the pathological and radiological findings and present a bibliographic review. METHODS: Castleman's disease is a rare benign disease of unknown etiology characterized by a lymphoproliferative disorder. Two clinical types have been described: localized and multicentric. Isolated retroperitoneal involvement is uncommon. RESULTS: 39-year-old female who complained of back pain. Abdominal CT scan identified a 5 cm retroperitoneal interaortocaval mass. Complete laparoscopic excision was performed. Pathological study showed localized angiofollicular hyperplasia (hyaline vascular type Castleman's disease). CONCLUSIONS: The presentation of Castleman's disease as isolated retroperitonealmass is quite rare and should be distinguished from other retroperitoneal lesions of malignant character. The treatment of choice is surgery, providing a definitive and curative diagnosis. Operative biopsy may be useful.

Enfermedad de Castleman. Una rara causa de masa retroperitoneal solitaria / Castleman's disease. A rare cause of isolated retroperitoneal mass

OBJETIVOS: Describimos un caso de enfermedad de Castleman variante hialino vascular de presentación unifocal como masa retroperitoneal. Se destacan hallazgos radiológicos y anatomopatológicos de esta enfermedad con revisión de la literatura. MÉTODOS: La enfermedad de Castleman es una rara enfermedad benigna de etiología desconocida caracterizada por un desorden linfoproliferativo. Puede presentarse de forma unifocal o multifocal. La afectación retroperitoneal aislada es infrecuente. RESULTADOS: Mujer de 39 años que consulta por lumbalgia. Se realiza TAC abdominal identificándose masa retroperitoneal de 5 cm interaortocava. Es intervenida mediante laparoscopia consiguiéndose la exéresis completa. El estudio anatomopatológico demostró hiperplasia angiofolicular localizada (variante hialino vascular de la enfermedad de Castleman). CONCLUSIONES: La presentación de la enfermedad de Castleman como masa retroperitoneal aislada es bastante infrecuente y debe distinguirse de otras lesiones retroperitoneales de carácter maligno. El tratamiento de elección es quirúrgico, aporta el diagnóstico definitivo, y resulta curativo. La biopsia operatoria puede ser de gran utilidad

OBJECTIVES: We describe a case of hyaline vascular type Castleman’s disease with unifocal presentation as retroperitoneal mass. We describe the pathological and radiological findings and present a bibliographic review. METHODS: Castleman’s disease is a rare benign disease of unknown etiology characterized by a lymphoproliferative disorder. Two clinical types have been described: localized and multicentric. Isolated retroperitoneal involvement is uncommon. RESULTS: 39-year-old female who complained of back pain. Abdominal CT scan identified a 5 cm retroperitoneal interaortocaval mass. Complete laparoscopic excision was performed. Pathological study showed localized angiofollicular hyperplasia (hyaline vascular type Castleman’s disease). CONCLUSIONS: The presentation of Castleman’s disease as isolated retroperitonealmass is quite rare and should be distinguished from other retroperitoneal lesions of malignant character. The treatment of choice is surgery, providing a definitive and curative diagnosis. Operative biopsy may be useful