Correlation of respiratory muscle strength with anthropometric variables of normal-weight and obese women.

OBJECTIVE: To correlate anthropometric data and respiratory muscle strength (RMS) of normal-weight and obese women. METHODS: The sample consisted of 103 sedentary women, divided into two groups: 57 obese and 46 normal-weight women. Waist circumference (WC) and hip circumference (HC) were measured to calculate the waist-to-hip ratio (WHR), and maximal respiratory pressures (Pmax) were determined using an analog vacuum manometer to ± 300 cm H2O. Body composition was measured using tetrapolar bioelectrical impedance analysis. Descriptive statistics was used for data analysis, in addition to the Student t test for independent samples, Pearson correlation, and stepwise multiple linear regression analysis. Significance level was set at p ≤ 0.05. RESULTS: The analysis showed significant differences in Pmax of normal-weight women (PImax = -73.04±16.55 cm H2O and PEmax = 79.67±18.89 cm H2O) and obese women (PImax = -85.00±21.69 cm H2O and PEmax = 103.86±20.35 cm H2O). Anthropometric and manometric variables showed no significant correlation in both groups. When analyzing the influence of bioelectrical impedance on RMS, a positive correlation was observed between lean body mass and PImax. CONCLUSION: Bioelectrical impedance and obesity showed a direct correlation with RMS. WC and WHR had no influence on RMS of obese women; however, a relevance to risk factors for associated diseases was observed. We believe that these results are due to an adjustment to excess body weight over the years.

Correlação da força muscular respiratória com variáveis antropométricas de mulheres eutróficas e obesas / Correlation of respiratory muscle strength with anthropometric variables of eutrophic and obese women

OBJETIVO: Correlacionar dados antropométricos e de FMR de mulheres eutróficas e obesas. MÉTODOS: A amostra foi formada por 103 mulheres sedentárias, dividas em dois grupos: 57 obesas e 46 eutróficas. Foram realizadas medidas da circunferência da cintura (CC) e do quadril (CQ) para cálculo da relação cintura/quadril (RC/Q) e coletados as Pressões Respiratórias Máximas (PRM) pela manovacuometria com aparelho analógico de ± 300cmH2O. Para a mensuração da composição corporal, utilizou-se a Bioimpedância Tetrapolar, análise descritiva com o teste T de Student para amostras independentes, correlação de Pearson e regressão linear múltipla com método stepwise. O nível de significância adotado foi p < 0,05. RESULTADOS: A análise demonstrou diferença significativa nas PRM de eutróficas (Pimáx = -73,04±16,55 cm H2O e Pemáx = 79,67±18,89 cm H2O) e de obesas (Pimáx = -85,00±21,69 cm H2O e Pemáx=103,86±20,35 cm H2O). As variáveis da antropometria e da manovacuometria não apresentaram correlação significante nos grupos. Ao analisar a influência da bioimpedância sobre a FMR, observou-se uma correlação positiva da quantidade de massa magra com a Pimáx. CONCLUSÃO: As variavéis da bioimpedância e a obesidade apresentaram uma relação direta com a FMR. As variáveis CC e RC/Q não influenciaram na FMR nas obesas, porém há uma relevância com os fatores de risco para doenças associadas. Acreditamos que esses resultados se devam a uma adaptação ao excesso de peso ao longo dos anos.

OBJECTIVE: To correlate anthropometrical data and RMS of eutrophic and obese women. METHODS: The study group comprised 103 sedentary women, divided into two groups: 57 obese and 46 eutrophic. For measurement of body composition, the Tetrapolar Bioimpedance was used. Measurements of waist and hip circumference were performed to calculate the waist/hip (W/H) ratio, and maximum respiratory pressures (MRP) were collected by analog manovacumeter with ± 300cm H2O. For data evaluation descriptive analysis and the Student's t Test for independent samples were used, as well as the Pearson correlation and multiple linear regression with stepwise method. The level of significance used was p < 0.05. RESULTS: Analysis showed a significant difference in MRPs of eutrophic (MIP = -73.04 ± 16.55cmH2O and MEP = 79.67 ± 18.89cmH2O) and obese (MIP = -85.00 ± 21.69cmH2O and MEP = 103.86 ± 20.35cmH2O). The anthropometry and manovacumetry variables showed no significant correlation in the groups. A positive correlation of the lean mass with the MIP was noted, when analising the bioimpedance influence on the RMS. CONCLUSION: The bioimpedance variables and obesity showed a direct relation with the RMS. The W/H ratio and WC variables had no influence on the obese RMS, however a relevance to the risk factors for associated diseases was found. We believe that these results are due to an adjustment to the excess weight over the years.

Insuficiência renal aguda causada por infusäo contínua de dextran-40: relato de um caso, com ênfase para sua fisiopatologia, e consideraçöes terapêuticas / Acute renal failure secondary to continous infusion of dextran-40: report on one case, with emphasis on its pathophysiology and therapeutic considerations

Um caso de insuficiência aguda (IRA) causada pela infusäo contínua de dextran-40(D-40) é relatado. Sua peculiar fisiopatologia, relacionada a reduçäo do clearance plasmático da substância, com conseqüente elevaçäo da pressäo colóido-osmótica do plasma e posterior parada da filtraçäo glomerular, é discutida. Uma revisäo da literatura é apresentada, com ênfase no uso da plasmaferese como método capaz de abreviar o período de disfunçäo renal