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1.
J Dent ; 73: 40-44, 2018 06.
Artículo en Inglés | MEDLINE | ID: mdl-29609017

RESUMEN

OBJECTIVES: This study determined whether consumption of calcium-containing gummies prior to fluoride varnish application enhances plaque fluoride retention and compliance with post-varnish application instructions. METHODS: The present study followed a multi-center, parallel, randomized, and laboratory analyst-blind design. Following IRB approval, parent consent and child assent, 44 subjects (7-12 years), were randomized to either gummy or no-gummy study groups. A baseline plaque sample was obtained after a wash-out period. Fluoride varnish (5% NaF) was applied; subjects in the gummy group received two calcium-containing gummies prior to varnish application. Subjects were given two questionnaires to complete (subject and parent) to investigate adherence to post-treatment instructions. Three days later, a second plaque sample was obtained. Plaque was analyzed for plaque fluid and solid fluoride concentrations. Fluoride data were analyzed using Wilcoxon Rank Sum tests, questionnaire data using Pearson chi-square tests. RESULTS: Plaque fluid fluoride did not change pre- to post-treatment in the gummy group (mean ±â€¯sd: 8.8 ±â€¯5.7 µmol/l vs. 10.0 ±â€¯6.3 µmol/l; p = 0.265) or in the no-gummy group (8.1 ±â€¯4.4 µmol/l vs. 16.1 ±â€¯20.0 µmol/l; p = 0.058). Groups were not different for plaque fluid fluoride pre-treatment (p = 1.000), post-treatment (p = 0.904), or change (p = 0.904). Plaque solid fluoride did not change pre- to post-treatment in the gummy group (0.89 ±â€¯1.10 µmol/g vs. 1.37 ±â€¯1.77 µmol/g; p = 0.073) or in the no-gummy group (0.68 ±â€¯0.77 µmol/g vs. 2.01 ±â€¯5.00 µmol/g; p = 0.190). Groups were not different for plaque solid fluoride pre-treatment (p = 1.000), post-treatment (p = 0.466), or change (p = 0.874). No significant differences were found between groups for questionnaire responses. CONCLUSION: This study failed to demonstrate an effect of calcium-containing gummies in enhancing plaque fluoride retention. CLINICAL SIGNIFICANCE: The consumption of calcium-containing gummies prior to fluoride varnish application does not promote greater intra-oral fluoride retention or better adherence to post-treatment instructions.


Asunto(s)
Calcio/uso terapéutico , Dulces , Placa Dental/tratamiento farmacológico , Fluoruros/uso terapéutico , Fosfatos de Calcio/uso terapéutico , Cariostáticos/uso terapéutico , Distribución de Chi-Cuadrado , Niño , Caries Dental/prevención & control , Combinación de Medicamentos , Femenino , Fluoruros Tópicos/uso terapéutico , Humanos , Masculino , Saliva , Tamaño de la Porción de Referencia , Fluoruro de Sodio/uso terapéutico , Encuestas y Cuestionarios
2.
Caries Res ; 51(5): 515-526, 2017.
Artículo en Inglés | MEDLINE | ID: mdl-28968608

RESUMEN

This study aimed to validate quantitative light-induced fluorescence (QLF) as a diagnostic tool for mild and moderate enamel fluorosis in permanent teeth, comparing it to visual diagnosis and histological assessment completed using polarized light microscopy (PLM). The buccal surfaces of 139 teeth were visually classified using the Thylstrup and Fejerskov Index (TFI) into sound (TFI 0; n = 17), mild (TFI 1-2; n = 69), and moderate (TFI 3-4; n = 43) fluorosis. Fluorosis was then assessed with QLF (variables ΔF, A, and ΔQ at 5-, 15-, and 30-radiance thresholds) using as reference areas the entire surface and a region of interest (ROI), identified as the most representative region of a fluorosis lesion. PLM images of longitudinal thin sections including the ROI were assessed for histological changes. Correlations among TFI, PLM, and QLF were determined. A receiver-operating characteristic curve was conducted to determine QLF's diagnostic accuracy when compared to the TFI and PLM assessments. This was used to assess the probability that the images were correctly ranked according to severity as determined by PLM and TFI. A positive correlation was found between QLF and PLM, and between QLF and TFI. QLF showed the highest sensitivity and specificity for the diagnosis of mild fluorosis. There was also a strong agreement between TFI and PLM. The selection of a ROI resulted in a stronger correlation with TFI and PLM than when the entire surface was used. The study results indicate that defining an ROI for QLF assessments is a valid method for the diagnosis of mild and moderate enamel fluorosis.


Asunto(s)
Dentición Permanente , Fluorosis Dental/diagnóstico , Imagen Óptica/métodos , Humanos , Técnicas In Vitro , Microscopía de Polarización
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