Efectos para la salud respiratoria de los trabajadores que usan sustancias químicas en su medio laboral. Una revisión sistemática

Introducción: A nivel laboral se presentan muchas afecciones en la salud de los trabajadores debido a riesgos químicos a los que están expuestos diariamente; a esto se suma la falta de compromiso de los empleadores con la salud de sus subordinados, ya que estos manejan diariamente sustancias químicas nocivas sin la debida protección personal. Objetivo: Identificar los efectos nocivos para la salud respiratoria de los trabajadores expuestos en su área laboral a sustancias químicas. Metodología: Se realizó una revisión sistemática de la literatura, se consideraron artículos de investigación realizados a partir de 2014 hasta 2020. Las palabras claves fueron "trabajadores" OR "laboral" AND "contaminantes" OR "agentes" AND "enfermedad reconocida", y se revisaron artículos de bases de datos como Google académico, SciELO (Scientific Electronic Library Online), ProQuest, Redalyc y Biblioteca Digital Universidad Cooperativa de Colombia. Conclusión: La salud de los trabajadores, sin importar en qué área laboral se desempeñen, se ve afectada en varios aspectos, los cuales pueden variar; entre ellos se encuentran los sistemas respiratorios, el sistema reproductor, el sistema nervioso, el sistema tegumentario y el sistema gastrointestinal de forma crónica o aguda. Entre los agentes más comunes causantes de las enfermedades respiratorias se reportan los pesticidas, el plomo y solventes.

Introduction: At work, there are many health conditions for workers due to chemical risks to which they are daily exposed, in addition to the lack of commitment of employers to the health of their subordinates, since they handle harmful chemical substances on a daily basis without proper personal protection. Objective: to identify the harmful effects for the respiratory health of workers exposed in their workplace to chemical substances. Methodology: A systematic review of the literature was carried out, research articles from 2014 to 2020 were considered. The keywords were "Workers" OR "Labor" AND "Contaminants" OR "Agents" AND "Recognized disease", and articles from databases such as Google Academic, SciELO (Scientific Electronic Library Online), ProQuest, Redalyc, and the Cooperative University of Colombia Digital Library were reviewed. Conclusion: The health of workers, regardless of their work area, is affected in several aspects which may vary. Among them, the respiratory systems, the reproductive system, the nervous system, the integumentary system, and the gastrointestinal system, in a chronic or acute manner. Among the most common causative agents of respiratory diseases are pesticides, lead, and solvents.

A complete assignment of the vibrational spectra of sucrose in aqueous medium based on the SQM methodology and SCRF calculations.

In the present study, a complete assignment of the vibrational spectra of sucrose in aqueous medium was performed combining Pulay's Scaled Quantum Mechanics Force Field (SQMFF) methodology with self-consistent reaction field (SCRF) calculations. Aqueous saturated solutions of sucrose and solutions at different molar concentrations of sucrose in water were completely characterized by infrared, HATR, and Raman spectroscopies. In accordance with reported data of the literature for sucrose, the theoretical structures of sucrose penta and sucrose dihydrate were also optimized in gas and aqueous solution phases by using the density functional theory (DFT) calculations. The solvent effects for the three studied species were analyzed using the solvation PCM/SMD model and, then, their corresponding solvation energies were predicted. The presence of pure water, sucrose penta-hydrate, and sucrose dihydrate was confirmed by using theoretical calculations based on the hybrid B3LYP/6-31G(∗) method and the experimental vibrational spectra. The existence of both sucrose hydrate complexes in aqueous solution is evidenced in the IR and HATR spectra by means of the characteristic bands at 3388, 3337, 3132, 1648, 1375, 1241, 1163, 1141, 1001, 870, 851, 732, and 668cm(-1) while in the Raman spectrum, the groups of bands in the regions 3159-3053cm(-1), 2980, 2954, and 1749-1496cm(-1) characterize the vibration modes of those complexes. The inter and intra-molecular H bond formations in aqueous solution were studied by Natural Bond Orbital (NBO) and Atoms in Molecules theory (AIM) investigation.

A complete assignment of the vibrational spectra of 2-furoic acid based on the structures of the more stable monomer and dimer.

The structural and vibrational properties of cyclic dimer of 2-furoic acid (2FA) were predicted by combining the available experimental infrared and Raman spectra in the solid phase and ab initio calculations based on density functional theory (DFT) with Pople's basis sets. The calculations show that there are two cyclic dimers for the title molecule that have been theoretically determined in the gas phase, and that only one of them, cis conformer, is present in the solid phase. The complete assignment of the 66 normal vibrational modes for the cis cyclic dimer was performed using the Pulay's Scaled Quantum Mechanics Force Field (SQMFF) methodology. Four strong bands in the infrared spectrum at 1583, 1427, 1126 and 887 cm(-1) and the group of bands in the Raman spectrum at 1464, 1452, 1147, 1030, 885, 873, 848, 715 and 590 cm(-1) are characteristic of the dimeric form of 2FA in the solid phase. In this work, the calculated structural and vibrational properties of both dimeric species were analyzed and compared between them. In addition, three types of atomic charges, bond orders, possible charge transfer, topological properties of the furan rings, Natural Bond Orbital (NBO) and Atoms in Molecules (AIM) theory calculations were employed to study the stabilities and intermolecular interactions of the both dimers of 2FA.

An experimental and theoretical study of L-Tryptophan in an aqueous solution, combining two-layered ONIOM and SCRF calculations.

ONIOM and SCRF calculations were performed to study the most stable theoretical structure of L-tryptophan in an aqueous solution phase and to observe the changes occurring in the structural and vibrational properties of L-tryptophan in the aqueous media. L-Tryptophan was characterized by infrared and Raman spectroscopies in the solid state and as an aqueous solution. Optimized geometries and relative stabilities for the L-tryptophan zwitterion were calculated while taking into account solvent effects using the self-consistent reaction field (SCRF) theory. The obtained results in the aqueous solution were compared with those calculated for the zwitterion in the gas phase by means of two-layered ONIOM calculations. For the complete assignments of the IR and Raman spectra of L-tryptophan in the aqueous solution phase, density functional theory (DFT) calculations were combined with Pulay's scaled quantum mechanical force field (SQMFF) methodology in order to fit the theoretical wavenumber values to the experimental values. Additionally, the roles of specific and bulk contributions from solvent effects on the properties of l-tryptophan were analyzed. Furthermore, bands corresponding to the normal modes of vibration were localized and assigned, and they served as the bases for the calculations of the corresponding force constants. Significant effects on the geometrical and vibrational frequencies were found for the studied zwitterion.

Síndrome de Munchausen por poderes con sintomatología psíquica. Ilustración de un caso clínico / Munchausen syndrome by proxy with a psiquic presentation. Case report

El Síndrome de Munchausen por poderes es un trastorno caracterizado por la simulación o producción intencionada de síntomas de alguna enfermedad orgánica o psíquica, siendo el sujeto de la enfermedad el niño y el agente productor de los síntomas uno de sus padres (con mayor frecuencia la madre). Tanto en el Síndrome de Munchausen como en el Síndrome de Munchausen por poderes se encuentra con más frecuencia la sintomatología orgánica; este trabajo aporta un ejemplo de presentación con sintomatología psíquica. Se abordan asimismo algunos problemas de clasificación diagnóstica de este Síndrome (AU)

Munchausen syndrome by proxy consists of an intended simulation or production of symptoms of any organic or psiquic illness, the child being the subject of the illness and one of the parents (usually the mother) the generating agent. Organic symptoms are more frequent in Munchausen Syndrome than in Munchausen Syndrome by Proxy. This paper provides an example of psychiatric presentation. Some diagnostic classification problems are also discussed (AU)