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Rev Esp Enferm Dig ; 115(4): 197-199, 2023 04.
Artículo en Inglés | MEDLINE | ID: mdl-35899688

RESUMEN

In this study we assessed the neutrophil-lymphocyte ratio (NLR) as a predictor of steroid non-response (SNR) in patients with acute severe ulcerative colitis and found a NLR on day 3 (NLR-3) >6.1 as a suitable cutoff point to identify SNR (OR 3.44, 95%CI 1.22-9.66) with sensitivity, specificity, positive predictive value, negative predictive value, and AUROC of 66.75, 63.2%, 35.9%, 86%, and 0.650, respectively. A model including bowel movements, albumin levels, and a NLR-3>6.1 had an AUC of 0.812 to predict SNR, with acceptable calibration.


Asunto(s)
Colitis Ulcerosa , Neutrófilos , Humanos , Colitis Ulcerosa/tratamiento farmacológico , Estudios Retrospectivos , Linfocitos , Esteroides/uso terapéutico , Pronóstico
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