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1.
Cureus ; 16(7): e64288, 2024 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-39130974

RESUMEN

Pyoderma gangrenosum (PG) is an uncommon inflammatory disorder that exhibits a range of clinical manifestations and levels of severity. It frequently occurs alongside an underlying condition, most often inflammatory bowel disease. PG, Sweet syndrome, palisaded neutrophilic granulomatous dermatitis (PNGD), interstitial granulomatous dermatitis (IGD) and rheumatoid neutrophilic dermatitis may be associated with rheumatoid arthritis (RA). We present a case of a 65-year-old woman with disseminated dermatosis to the hands, abdomen, buttocks, and lower limbs. The dermatosis presented with numerous ulcers of varying shapes, featuring clean bases, undermined edges, and a purplish erythematous appearance. Further investigations, including imaging studies and RA factor and anti-cyclic citrullinated peptide (anti-CCP) levels, led us to the diagnosis of RA. This case indicates that RA may be frequently undiagnosed and untreated in other patients with PG, as ulcers on the lower extremities can often be the main reason for seeking medical attention.

3.
Cureus ; 16(4): e59226, 2024 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-38807846

RESUMEN

Bullous pemphigoid is a subepidermal blistering disease that rarely involves the mucous membranes and possesses circulating antibodies against BP antigen II (BP180) and BP antigen I (BP230). Rheumatoid arthritis (RA) is a progressive inflammatory autoimmune disease that is characterized by joint inflammation and systemic involvement. The co-occurrence of RA, which is likewise linked to autoimmunity, with bullous pemphigoid may not be merely coincidental. A 55-year-old female, a known case of RA for 25 years, presented to us with multiple pruritic vesiculobullous lesions. After a thorough clinical and laboratory assessment, she was diagnosed with bullous pemphigoid. This emphasizes the significance of the simultaneous occurrence of autoimmune disorders and the need for vigilant and timely identification.

4.
Cureus ; 16(3): e56600, 2024 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-38646262

RESUMEN

Reticulate pigmentary disorders are autosomal dominant pigmentary disorders caused by abnormalities in the keratin 5 and keratin 14 genes. Here, we report three cases of reticulate hyperpigmentation disorders with clinical overlaps of the reticulate acropigmentation of Kitamura, Dowling-Degos disease (DDD), and dyschromatosis symmetrica hereditaria (DSH), all three having limited treatment options.

5.
Cureus ; 14(8): e28126, 2022 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-36134070

RESUMEN

A common cervical spine condition that frequently interferes with a patient's daily activities is chronic neck pain. The axioscapular muscle imbalance that results from increased middle trapezius activity in patients with non-specific chronic neck pain affects cervical spine stability and contributes to pain. A 67-year-old male, who was a retired office secretary, experienced neck pain for two years. In the last four months, his discomfort worsened, impairing his ability to function and degrading his quality of life. For the axioscapular muscle imbalance, scapular repositioning with a scapular belt was used to alleviate muscular imbalances and help with posture correction. The results were calculated using the Numerical Pain Rating Scale (NPRS) and the Neck Disability Index (NDI), which revealed significant changes in pain intensity from 9 to 4, and disability scores shifted from 48% to 20% between the pre and post-treatment sessions, respectively. In order to decrease neck pain, this case report investigates the impact of scapular realignment using a scapular belt in the treatment of non-specific chronic neck discomfort.

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