Joint action with human and robotic co-actors: Self-other integration is immune to the perceived humanness of the interacting partner.

When performing a joint action task, we automatically represent the action and/or task constraints of the co-actor with whom we are interacting. Current models suggest that, not only physical similarity, but also abstract, conceptual features shared between self and the interacting partner play a key role in the emergence of joint action effects. Across two experiments, we investigated the influence of the perceived humanness of a robotic agent on the extent to which we integrate the action of that agent into our own action/task representation, as indexed by the Joint Simon Effect (JSE). The presence (vs. absence) of a prior verbal interaction was used to manipulate robot's perceived humanness. In Experiment 1, using a within-participant design, we had participants perform the joint Go/No-go Simon task with two different robots. Before performing the joint task, one robot engaged in a verbal interaction with the participant and the other robot did not. In Experiment 2, we employed a between-participants design to contrast these two robot conditions as well as a human partner condition. In both experiments, a significant Simon effect emerged during joint action and its amplitude was not modulated by the humanness of the interacting partner. Experiment 2 further showed that the JSE obtained in robot conditions did not differ from that measured in the human partner condition. These findings contradict current theories of joint action mechanisms according to which perceived self-other similarity is a crucial determinant of self-other integration in shared task settings.

Mind your heart to bear the weight: Cardiac interoception predicts action-related visual perception when wearing a heavy backpack.

Visual perception can be modulated by the physiological potential for action. For instance, it was famously shown that a geographical slant appears steeper when wearing a heavy backpack than not wearing any. However, those results are not always replicated. In the present exploratory study, we test the hypothesis that the backpack weight's effect on perception relies on the ability of the cognitive system to integrate the physiological constraint's change rather than the change itself. Young adults (n = 54) wore an electrocardiogram monitor and completed a computerised task in which photographs of real geographical slants were displayed on a screen while wearing a heavy versus light backpack. The activity of the vagus nerve, as an index of physiological adaptability, was recorded as a proxy of the physiological state during the task. The participants also completed an interoception task assessing one's ability to detect his or her own heartbeat as the index of integration ability of the cognitive system. While Bayesian analyses revealed no difference in angle estimation between carrying a heavy versus light backpack, the results indicated that interoception predicted less accurate angle estimation only when wearing a heavy backpack. In contrast, there was anecdotal evidence that vagal activity changes predicted visual perception. Interoception might thus play a crucial role in the interplay between the physiological potential for action and action-related visual perception.

Does heart rate variability predict better executive functioning? A systematic review and meta-analysis.

The recent focus on the bidirectional heart-brain interactions in psychoneurophysiological research has led to a variety of findings suggesting vagal activity is associated with cognition and, possibly, specifically with executive functioning. This systematic review and meta-analysis aimed to provide a better understanding of the association between vagally-mediated heart rate variability (HRV) and executive functioning. We included 13 correlational studies. We found a small positive association between vagally-mediated HRV and executive functioning (r = .19, 95% CI .15 to .23, p < .0001) using a quantitative synthesis of existing studies with random-effect models. Conducting meta-regression analyses, we found that vagally-mediated HRV predicts cognitive inhibition and cognitive flexibility more than working memory. In addition to the specific executive function measured, this relationship is moderated by the HRV measurement used, and age. After proposing a theoretical interpretation of the results, we emphasized the need for further research in light of the methodological issues identified in the included studies, and we outline several aspects to consider in future studies.

Beneficial Effects of Linseed Supplementation on Gut Mucosa-Associated Microbiota in a Physically Active Mouse Model of Crohn's Disease.

The Western diet, rich in lipids and in n-6 polyunsaturated fatty acids (PUFAs), favors gut dysbiosis observed in Crohn's disease (CD). The aim of this study was to assess the effects of rebalancing the n-6/n-3 PUFA ratio in CEABAC10 transgenic mice that mimic CD. Mice in individual cages with running wheels were randomized in three diet groups for 12 weeks: high-fat diet (HFD), HFD + linseed oil (HFD-LS-O) and HFD + extruded linseed (HFD-LS-E). Then, they were orally challenged once with the Adherent-Invasive Escherichia coli (AIEC) LF82 pathobiont. After 12 weeks of diet, total energy intake, body composition, and intestinal permeability were not different between groups. After the AIEC-induced intestinal inflammation, fecal lipocalin-2 concentration was lower at day 6 in n-3 PUFAs supplementation groups (HFD-LS-O and HFD-LS-E) compared to HFD. Analysis of the mucosa-associated microbiota showed that the abundance of Prevotella, Paraprevotella, Ruminococcus, and Clostridiales was higher in the HFD-LS-E group. Butyrate levels were higher in the HFD-LS-E group and correlated with the Firmicutes/Proteobacteria ratio. This study demonstrates that extruded linseed supplementation had a beneficial health effect in a physically active mouse model of CD susceptibility. Additional studies are required to better decipher the matrix influence in the linseed supplementation effect.

When does vagal activity benefit to the discrimination of highly overlapping memory traces?

Distinguishing among similar events is indeed crucial to memory. In a dangerous context, this ability may be less essential, whereas in a secure context it may provide an adaptative advantage notably in social situations. Vagal activity as a marker of the individual's adaptation in social engagement contexts might predict the ability to discriminate highly similar memories in an unthreatening context. The present study aims to test the relation between vagal activity and memory discrimination by manipulating the visual distinctiveness of stimuli (high vs. low) in an ecological memory discrimination task with humanoid characters. It was expected that vagal activity support adaptive self-regulatory processes which may be needed only when the memory discrimination is challenging (low distinctiveness between true memory and lure). In a study phase, multiple realistic fictional humanoid characters performed the same action on different objects. The characters could be very similar or very distinct one to each other. Then, during a test phase, the participants had to discriminate whether a displayed character on the screen was exactly matched the one performing the given action on a specific object in the study phase (target). Vagal activity was assessed in undergraduate students (n = 40) before the study phase. Higher vagal activity predicted better memory discrimination performance specifically when the distinctiveness between the lure and target was low. These data extend previous work on vagal activity and memory suggesting that heart-brain interactions represent an adaptive psychophysiological mechanism underlying memory discrimination specifically when it is challenging in an unthreatening context.

Some further clarifications on age-related differences in the Stroop task: New evidence from the two-to-one Stroop paradigm.

Previous studies (Augustinova et al., Psychonomic Bulletin & Review, 25(2), 767-774, 2018; Li & Bosman, Aging, Neuropsychology, and Cognition, 3(4), 272-284, 1996) have shown that the larger Stroop effects reported in older adults is specifically due to age-related differences in the magnitude of response - and not semantic - conflict, both of which are thought to contribute to overall Stroop interference. However, the most recent contribution to the issue of the unitary versus composite nature of the Stroop effect argues that semantic conflict has not been clearly dissociated from response conflict in these or any other past Stroop studies, meaning that the very existence of semantic conflict is at present uncertain. To distinguish clearly between the two types of conflict, the present study employed the two-to-one Stroop paradigm with a color-neutral word baseline. This addition made it possible to isolate a contribution of semantic conflict that was independent of both response conflict and Stroop facilitation. Therefore, this study provides the first unambiguous empirical demonstration of the composite nature of Stroop interference - as originally claimed by multi-stage models of Stroop interference. This permitted the further observation of significantly higher levels of semantic conflict in older adults, whereas the level of response conflict in the present study remained unaffected by healthy aging - a finding that directly contrasts with previous studies employing alternative measures of response and semantic conflict. Two qualitatively different explanations of this apparent divergence across studies are discussed.

Is There Semantic Conflict in the Stroop Task?

This research addressed current controversies concerning the contribution of semantic conflict to the Stroop interference effect and its reduction by a single-letter coloring and cueing procedure. On the first issue, it provides, for the first time, unambiguous evidence for a contribution of semantic conflict to the (overall) Stroop interference effect. The reported data remained inconclusive on the second issue, despite being collected in a considerable sample and analyzed with both classical (frequentist) and Bayesian inferential approaches. Given that in all past Stroop studies, semantic conflict was possibly confounded with either response conflict (e.g., when semantic-associative items [SKYblue] are used to induce semantic conflict) or with facilitation (when color-congruent items [BLUEblue] are used as baseline to derive a magnitude for semantic conflict), its genuine contribution to the Stroop interference effect is the most critical result reported in the present study. Indeed, it leaves no doubt - in complete contrast to dominant single-stage response competition models (e.g., Roelofs, 2003) - that selection occurs at the semantic level in the Stroop task. The immediate implications for the composite (as opposed to unitary) nature of the Stroop interference effect and other still unresolved issues in the Stroop literature are outlined further.

Spatial periodicities inside the Talbot effect: understanding, control and applications for lithography.

Displacement Talbot Lithography (DTL) is a simple patterning technique for creating periodic sub-micron features on wafer areas up to 200 mm diameter for applications in, for example, plasmonic, photonic crystals, and metamaterials. It exploits the diffraction and interference generally avoided in classical lithography. The Talbot effect, on which DTL is based, is the periodic spatial repetition of a periodic mask illuminated by coherent light. The modelling of this phenomenon is essential to fully understand and predict the interference pattern obtained; for mask periods greater than twice the wavelength, new spatial periodicities are generally introduced that are smaller than the Talbot length. This study reports simulations of multiple 1D masks to explain the influence of these smaller spatial periodicities on the Talbot effect. By changing the mask configuration, one can tailor the spatial periodicity contributions and thus, control the feature size, uniformity, and contrast for Talbot-effect-based lithography.

Stroop interference is a composite phenomenon: Evidence from distinct developmental trajectories of its components.

Only one previous developmental study of Stroop task performance (Schiller, 1966) has controlled for differences in processing speed that exist both within and between age groups. Therefore, the question of whether the early developmental change in the magnitude of Stroop interference actually persists after controlling for processing speed needs further investigation; work that is further motivated by the possibility that any remaining differences would be caused by process(es) other than processing speed. Analysis of data from two experiments revealed that, even after controlling for processing speed using z-transformed reaction times, early developmental change persists such that the magnitude of overall Stroop interference is larger in 3rd- and 5th graders as compared to 1st graders. This pattern indicates that the magnitude of overall Stroop interference peaks after 2 or 3 years of reading practice (Schadler & Thissen, 1981). Furthermore, this peak is shown to be due to distinct components of Stroop interference (resulting from specific conflicts) progressively falling into place. Experiment 2 revealed that the change in the magnitude of Stroop interference specifically results from joint contributions of task, semantic and response conflicts in 3rd- and 5th graders as compared to a sole contribution of task conflict in 1st graders. The specific developmental trajectories of different conflicts presented in the present work provide unique evidence for multiple loci of Stroop interference in the processing stream (respectively task, semantic and response conflict) as opposed to a single (i.e. response) locus predicted by historically - favored response competition accounts.

Attentional bias modification with a new paradigm: The effect of the Detection Engagement and Savoring Positivity (DESP) task on eye-tracking of attention.

BACKGROUND AND OBJECTIVES: We tested the effect of a new Attentional Bias Modification (ABM) task - the Detection Engagement and Savoring Positivity (DESP) task - on attentional biases. The DESP is innovative in that it involves a procedure of savoring the positivity of various pictures. METHODS: Participants were randomly assigned to the DESP or to a placebo control condition (experiment 1; n = 38) or a condition controlling for savoring (experiment 2; n = 54) in a pre-post/training experimental design. During one week, the participants completed the DESP or the control task once a day between three and six times. We assessed the effects of the DESP task on various attentional biases (i.e. positive, negative and threat) by computing dwell time from an eye-tracking technology before and after the training, and also one week after the post-training session in experiment 2. RESULTS: In both experiments, the attentional bias toward positive stimuli between the pre- and the post-training increased significantly more in the DESP task condition than in the control conditions. Negative and threat attentional biases were not significantly affected by the experimental manipulations. Experiment 2 revealed that the DESP task - including the savoring instruction - increased significantly more the positive attentional bias than a task excluding this step and that this effect remained significant one week after the post-training session. LIMITATIONS: Our samples were mainly composed of women participants. This prevents generalization of the findings. CONCLUSIONS: The DESP task offers promising perspectives for sustainably improving attention to positive information.

Displacement Talbot lithography for nano-engineering of III-nitride materials.

Nano-engineering III-nitride semiconductors offers a route to further control the optoelectronic properties, enabling novel functionalities and applications. Although a variety of lithography techniques are currently employed to nano-engineer these materials, the scalability and cost of the fabrication process can be an obstacle for large-scale manufacturing. In this paper, we report on the use of a fast, robust and flexible emerging patterning technique called Displacement Talbot lithography (DTL), to successfully nano-engineer III-nitride materials. DTL, along with its novel and unique combination with a lateral planar displacement (D2TL), allow the fabrication of a variety of periodic nanopatterns with a broad range of filling factors such as nanoholes, nanodots, nanorings and nanolines; all these features being achievable from one single mask. To illustrate the enormous possibilities opened by DTL/D2TL, dielectric and metal masks with a number of nanopatterns have been generated, allowing for the selective area growth of InGaN/GaN core-shell nanorods, the top-down plasma etching of III-nitride nanostructures, the top-down sublimation of GaN nanostructures, the hybrid top-down/bottom-up growth of AlN nanorods and GaN nanotubes, and the fabrication of nanopatterned sapphire substrates for AlN growth. Compared with their planar counterparts, these 3D nanostructures enable the reduction or filtering of structural defects and/or the enhancement of the light extraction, therefore improving the efficiency of the final device. These results, achieved on a wafer scale via DTL and upscalable to larger surfaces, have the potential to unlock the manufacturing of nano-engineered III-nitride materials.

"Double" displacement Talbot lithography: fast, wafer-scale, direct-writing of complex periodic nanopatterns.

We describe a new low-cost nanolithographic tool for creating periodic arrays of complex, nano-motifs, across large areas within minutes. Displacement Talbot lithography is combined with lateral nanopositioning to enable large-area patterning with the flexibility of a direct-write system. In this way, we can create different periodic patterns in short timescales using a single mask with no mask degradation. We demonstrate multiple exposures, combined with discrete lateral displacements, and single exposures, with continuous displacements, to achieve image inversion, pitch reduction, and nanogaps between metal nanoparticles. Our approach provides a flexible route to create large-area nanopatterned materials and devices in high volumes.

How to Measure Sedentary Behavior at Work?

Background: Prolonged sedentary behavior (SB) is associated with increased risk for chronic conditions. A growing number of the workforce is employed in office setting with high occupational exposure to SB. There is a new focus in assessing, understanding and reducing SB in the workplace. There are many subjective (questionnaires) and objective methods (monitoring with wearable devices) available to determine SB. Therefore, we aimed to provide a global understanding on methods currently used for SB assessment at work. Methods: We carried out a systematic review on methods to measure SB at work. Pubmed, Cochrane, Embase, and Web of Science were searched for peer-reviewed English-language articles published between 1st January 2000 and 17th March 2019. Results: We included 154 articles: 89 were cross-sectional and 65 were longitudinal studies, for a total of 474,091 participants. SB was assessed by self-reported questionnaires in 91 studies, by wearables devices in also 91 studies, and simultaneously by a questionnaire and wearables devices in 30 studies. Among the 91 studies using wearable devices, 73 studies used only one device, 15 studies used several devices, and three studies used complex physiological systems. Studies exploring SB on a large sample used significantly more only questionnaires and/or one wearable device. Conclusions: Available questionnaires are the most accessible method for studies on large population with a limited budget. For smaller groups, SB at work can be objectively measured with wearable devices (accelerometers, heart-rate monitors, pressure meters, goniometers, electromyography meters, gas-meters) and the results can be associated and compared with a subjective measure (questionnaire). The number of devices worn can increase the accuracy but make the analysis more complex and time consuming.

Preventive Effect of Spontaneous Physical Activity on the Gut-Adipose Tissue in a Mouse Model That Mimics Crohn's Disease Susceptibility.

Crohn's disease is characterized by abnormal ileal colonization by adherent-invasive E. coli (AIEC) and expansion of mesenteric adipose tissue. This study assessed the preventive effect of spontaneous physical activity (PA) on the gut-adipose tissue in a mouse model that mimics Crohn's disease susceptibility. Thirty-five CEABAC10 male mice performed spontaneous PA (wheel group; n = 24) or not (controls; n = 11) for 12 weeks. At week 12, mice were orally challenged with the AIEC LF82 strain for 6 days. Body composition, glycaemic control, intestinal permeability, gut microbiota composition, and fecal short-chain fatty acids were assessed in both groups. Animals were fed a high fat/high sugar diet throughout the study. After exposure to AIEC, mesenteric adipose tissue weight was lower in the wheel group. Tight junction proteins expression increased with spontaneous PA, whereas systemic lipopolysaccharides were negatively correlated with the covered distance. Bifidobacterium and Lactobacillus decreased in controls, whereas Oscillospira and Ruminococcus increased in the wheel group. Fecal propionate and butyrate were also higher in the wheel group. In conclusion, spontaneous physical activity promotes healthy gut microbiota composition changes and increases short-chain fatty acids in CEABAC10 mice fed a Western diet and exposed to AIEC to mimic Crohn's disease.

Hybrid Top-Down/Bottom-Up Fabrication of a Highly Uniform and Organized Faceted AlN Nanorod Scaffold.

As a route to the formation of regular arrays of AlN nanorods, in contrast to other III-V materials, the use of selective area growth via metal organic vapor phase epitaxy (MOVPE) has so far not been successful. Therefore, in this work we report the fabrication of a highly uniform and ordered AlN nanorod scaffold using an alternative hybrid top-down etching and bottom-up regrowth approach. The nanorods are created across a full 2-inch AlN template by combining Displacement Talbot Lithography and lift-off to create a Ni nanodot mask, followed by chlorine-based dry etching. Additional KOH-based wet etching is used to tune the morphology and the diameter of the nanorods. The resulting smooth and straight morphology of the nanorods after the two-step dry-wet etching process is used as a template to recover the AlN facets of the nanorods via MOVPE regrowth. The facet recovery is performed for various growth times to investigate the growth mechanism and the change in morphology of the AlN nanorods. Structural characterization highlights, first, an efficient dislocation filtering resulting from the ~130 nm diameter nanorods achieved after the two-step dry-wet etching process, and second, a dislocation bending induced by the AlN facet regrowth. A strong AlN near band edge emission is observed from the nanorods both before and after regrowth. The achievement of a highly uniform and organized faceted AlN nanorod scaffold having smooth and straight non-polar facets and improved structural and optical quality is a major stepping stone toward the fabrication of deep UV core-shell-based AlN or AlxGa1-xN templates.

Not as bad as it seems: When the presence of a threatening humanoid robot improves human performance.

"Bad" humanoid robots just paying attention to human performance may energize attentional control-as does human presence.

A Simulation-Based Comparison of Covariate Adjustment Methods for the Analysis of Randomized Controlled Trials.

Covariate adjustment methods are frequently used when baseline covariate information is available for randomized controlled trials. Using a simulation study, we compared the analysis of covariance (ANCOVA) with three nonparametric covariate adjustment methods with respect to point and interval estimation for the difference between means. The three alternative methods were based on important members of the generalized empirical likelihood (GEL) family, specifically on the empirical likelihood (EL) method, the exponential tilting (ET) method, and the continuous updated estimator (CUE) method. Two criteria were considered for the comparison of the four statistical methods: the root mean squared error and the empirical coverage of the nominal 95% confidence intervals for the difference between means. Based on the results of the simulation study, for sensitivity analysis purposes, we recommend the use of ANCOVA (with robust standard errors when heteroscedasticity is present) together with the CUE-based covariate adjustment method.

'Do Well B.': Design Of WELL Being monitoring systems. A study protocol for the application in autism.

INTRODUCTION: Individuals with autism spectrum disorder (ASD) have difficulties in communication and social interaction resulting from atypical perceptual and cognitive information processing, leading to an accumulation of anxiety. Extreme overloading experienced internally may not be externally visible. Identifying stressful situations at an early stage may avoid socially problematic behaviour from occurring, such as self-injurious behaviour. Activation of the autonomous nervous system (ANS) is involved in the response to anxiety, which can be measured through heart rate variability and skin conductance with the use of portable devices, non-intrusively and pain-free. Thus, developing innovative analysis of signal perception and reaction is necessary, mainly for non-communicative individuals with autism. METHODS AND ANALYSIS: The protocol will take place in real life (home and social environments). We aim to associate modifications of the ANS with external events that will be recorded in a synchronous manner through a specific design (spy glasses with video/audio recording). Four phases will be carried out on ASD participants and aged-matched controls: (1) 24-hour baseline pre-experiment (physical activity, sleep), (2) 2 h in a real life situation, (3) 30 min in a quiet environment, interrupted by a few seconds of stressful sound, (4) an interview to record feelings about events triggering anxiety. ASD and control participants will be together for phases 2 and 3, revealing different physiological responses to the same situations, and thus identifying potentially problematic events. The novelty will be to apply time-series analyses (which led to several Nobel Prizes in quantitative finance) on ANS series (heart rate, heart rate variability, skin conductance) and wrist motion. ETHICS AND DISSEMINATION: Ethical approval has been obtained from Ethics Committee of Clermont-Ferrand (South-East I), France (2014-A00611-46). Trial findings will be disseminated via open-access peer-reviewed publications, conferences, clinical networks, public lectures and our websites. TRIAL REGISTRATION NUMBER: ClinicalTrials identifier NCT02275455.