[Itching: differential diagnosis and therapy].

The lecture deals with the differential diagnosis and treatment of diseases accompanied by itching. It considers the major components of its pathogenesis, which are important to provide a rationale for its therapy. Particular emphasis is laid on the analysis of the most common classifications of the causes of itching, which take into account both pathogenetic and clinical parameters. The main differentially diagnostic signs of dermal and nondermal diseases attended by itching are given. Antihistamines among the agents intended for itching therapy are considered in detail. The efficacy and safety of first- and second-generation antihistamines, including quinuclidine derivatives, are comparatively analyzed.

[Isolation of blood eosinophils in multi-step density gradient]. / Vydelenie éozinofilov krovi v mnogostupenchatom gradiente.

The density and morphology of blood eosinophils from 60 children with atopic dermatitis were investigated. The proportion of hypodense eosinophils is higher during the acute stage of disease than during remission (59.78 +/- 0.20% vs. 21.40 +/- 0.04%).

[Manifestations of pseudo-allergy in different diseases in children]. / Proiavleniia psevdoallergii pri razlichnykh zabolevaniiakh u detei.

Fifty-seven children aged 1 to 14 years with pseudoallergic reactions were followed up. The reactions manifested in the form of eczema, neurodermatitis, urticaria, and Quincke's edema. All the patients showed different pathology associated with the above-indicated skin reactions. The infants presented with the hypertensive hydrocephalic syndrome whereas the elder children with vegetovascular dystonia, biliary and gastrointestinal diseases. The treatment of the revealed pathological process, that included administration of histaglobulin or zaditen, brought about well-defined positive clinical changes.