Social participation and drug use in a cohort of Brazilian sex workers.

BACKGROUND: Structural interventions focused on community mobilisation to engender an enabling social context have reduced sexual risk behaviours among sex workers. Interventions to date have increased social participation and shown an association between participation and safer sex. Social participation could modify risk for other health behaviours, particularly drug use. We assessed social participation and drug use before and after implementation of a clinical, social and structural intervention with sex workers intended to prevent sexually transmitted infections/HIV infection. METHODS: We followed 420 sex workers participating in the Encontros intervention in Corumbá, Brazil, between 2003 and 2005. We estimated the association of participation in external social groups with drug use at baseline and follow-up using logistic regression and marginal modelling. Follow-up analyses of preintervention/postintervention change in drug use employed inverse probability weighting to account for censoring and were stratified by exposure to the intervention. RESULTS: Social participation showed a protective association with drug use at baseline (1 SD higher level of social participation associated with 3.8% lower prevalence of drug use, 95% CI -0.1 to 8.3). Among individuals exposed to Encontros, higher social participation was associated with an 8.6% lower level of drug use (95% CI 0.1 to 23.3). No significant association was found among the unexposed. CONCLUSIONS: A structural intervention that modified sex workers' social environment, specifically participation in external social groups, was associated with reduced drug use. These findings suggest that sexual risk prevention initiatives that enhance social integration among marginalised populations can produce broad health impacts, including reductions in drug use.

Findings from Encontros: a multilevel STI/HIV intervention to increase condom use, reduce STI, and change the social environment among sex workers in Brazil.

BACKGROUND: Sexually transmitted infection (STI)/HIV prevention programs, which do not modify social structural contexts that contribute to risk of STI/HIV may fail to bring about improvements in health, particularly among groups who experience discrimination and exclusion from public life. We conducted a multilevel intervention with sex workers, including improved clinical care and community-mobilizing strategies to modify social structural factors that shape sexual behavior, to improve condom use and reduce incident STI. METHODS: We followed 420 sex workers participating in the Encontros intervention in Corumbá, Brazil, between 2003 and 2005. We estimated the effect of the intervention on incident chlamydia and gonorrhea infections and condom use using generalized estimating equations and inverse probability weighting by comparing those who actively engaged in the intervention activities (exposed) with those who were less engaged (unexposed). We also determined the association of participation on reported social cohesion and participation in networks. RESULTS: Exposed participants had significantly higher odds of reporting consistent condom use with regular clients (odds ratio [OR]: 1.9, 95% confidence interval:1.1-3.3) and nonsignificantly increased odds with both new clients (OR: 1.6, 0.9-2.8) and nonpaying partners (OR: 1.5, 0.9-1.5). The odds of an incident STI were nonsignificantly reduced for exposed participants compared with unexposed (OR: 0.46, 0.2-1.3). Participation was significantly associated with increased perceived cohesion and participation in networks. CONCLUSION: This prospective study provides evidence that multilevel interventions with mobilizing strategies to modify aspects of the social environment can improve condom use, reduce STIs, and increase social cohesion and participation in networks among sex workers.

Prevalence and factors associated with HSV-2 and hepatitis B infections among truck drivers crossing the southern Brazilian border.

OBJECTIVES: The authors estimate the prevalence of HIV, syphilis, hepatitis B virus (HBV) and herpes simplex virus type-2 (HSV-2) infection and correlates of HBV and HSV-2 infection among truck drivers crossing the southern Brazilian border at Foz do Iguaçu. METHODS: Between October 2003 and March 2005, 1945 truck drivers were sampled while accessing voluntary counselling and testing services; 1833 (94.2%) were tested for HIV (ELISA and confirmatory immunofluorescence assay) and syphilis (non-treponemal (VDRL) and treponemal tests (FTA-ABS)). From these, 799 stored sera were tested for HSV-2 (type-specific ELISA test for detection of IgG) and HBV (core antibodies (anti-HBc) with positives tested for surface antigen (HBsAg)). The authors estimate HIV, syphilis, HSV-2 and HBV prevalence and determine socio-demographic and behavioural correlates of HSV-2 infection and HBV exposure. RESULTS: HIV prevalence was 0.3% (95% CI 0.1 to 0.6) and syphilis 4.5% (95% CI 3.6 to 5.4). Among those tested for HBV and HSV-2, 32.3% (95% CI 28.9 to 35.6) had serological evidence of exposure to HBV and 26.6% (95% CI 23.5 to 29.7) tested positive for HSV-2. Factors independently associated with HBV exposure included increasing age, Brazilian nationality and unprotected anal sex. Increasing age and reporting an unknown number of lifetime partners were associated with HSV-2 infection. CONCLUSIONS: In this sample of truck drivers in southern Brazil, HIV prevalence was lower than national population estimates; exposure to HBV was higher than population estimates, while per cent positive for HSV-2 was similar to population estimates. The low prevalence of HIV in truck drivers indicates prevention successes; however, future HIV prevention programming should incorporate HBV vaccination and sexually transmitted infection prevention.

Social-environmental factors and protective sexual behavior among sex workers: the Encontros intervention in Brazil.

OBJECTIVES: We sought to determine the association of social-environmental factors with condom use and sexually transmitted infections (STIs) among 420 sex workers participating in an STI/HIV prevention study in Corumbá, Brazil, to inform future intervention efforts. METHODS: Participants provided urine samples for polymerase chain reaction testing of chlamydia and gonorrhea and responded to multi-item scales addressing perceived social cohesion, participation in networks, and access to and management of resources. We conducted multivariate log-linear and negative binomial regression analyses of these data. RESULTS: Increased social cohesion was inversely associated with number of unprotected sex acts in the preceding week among women (adjusted incidence rate ratio [IRR] = 0.80; P < .01), and there was a marginal association among men (adjusted IRR = 0.41; P = .08). Women's increased participation in social networks was associated with a decrease in frequency of unprotected sex acts (adjusted IRR = 0.83; P = .04), as was men's access to and management of social and material resources (IRR = 0.15; P = .01). Social-environmental factors were not associated with STIs. CONCLUSIONS: The social context within which populations negotiate sexual behaviors is associated with condom use. Future efforts to prevent STI/HIV should incorporate strategies to modify the social environment.

Mobility and its liminal context: exploring sexual partnering among truck drivers crossing the Southern Brazilian border.

Mobile populations, including truck drivers, are at elevated risk of acquiring HIV and other sexually transmitted infections (STI). However, measures of mobility have been poorly operationalized and little research exists exploring the psychosocial context of mobility and sexual risk taking. A systematic sample of 1775 male truck drivers underwent interview at two customs stations on the Southern Brazilian international border in 2003. The psychosocial effect of being mobile was assessed by clustering truckers based on perceptions of the liminal environment, or being outside of one's normal social environment. The relationship between physical mobility (nights spent at home) and liminal cluster with sexual partnerships was assessed. The clustering procedure yielded three dispositions towards the liminal environment. Compared to truckers in the baseline cluster, those who perceive the environment as (1) very, or (2) moderately permissive had increased odds of reporting a commercial sex partner in the past six months and reported increased numbers of commercial partners. For each week slept at home, the odds of reporting a commercial partner decreased by a factor of 0.73 and the average number of commercial partners decreased by a rate of 0.76. Physical and psychosocial measures of mobility were associated independently with increased partnering on the road. Additional exploration of how the liminal environment shapes mobile populations' sexual decision making and vulnerability to STI is warranted.

Chaos, co-existence, and the potential for collective action: HIV-related vulnerability in Brazil's international borders.

In a country where quality HIV/AIDS prevention and care has been foremost on the national agenda, Brazil's extensive and diverse borders are one of the last unstudied potential hotbeds of HIV vulnerability. We carried out a rapid assessment of HIV-related services and the social context of HIV/AIDS at the Brazilian borders including current governmental and community response. The assessment was implemented in six frontier municipalities using the WHO's strategic approach methodology, which combines existing epidemiologic data with field-based qualitative data collection techniques, including observation of service delivery points and in-depth interviews and focus groups with local leaders, providers, and community members, in order to recommend context-specific HIV prevention strategies. This paper focuses on the qualitative findings regarding the role of the social context in shaping HIV vulnerability at the Brazilian borders. We documented a profound lack of governmental structure and response to HIV/AIDS at the borders as well as a notable absence of social cohesion and mobilization among the diverse population groups and communities situated at the borders with regard to HIV/AIDS. The weak governmental and community response is situated within a larger socio-political context of economic inequity and social division, which must be addressed if an effective response to HIV can be developed at Brazil's international borders. Possibilities for encouraging a collective response among the diverse border populations are explored.

Obstetric and perinatal outcomes in multiparous adolescents

Objetivo: comparar os resultados obstétricos e perinatais de adolescentes multíparas com dois grupos de gestantes: adolescentes primíparas e adultas multíparas. O estudo incluiu 199 adolescentes multíparas, que foram comparadas com 398 adolescentes primíparas e 398 adultas multíparas. Os critérios de exclusão foram: presença de doença materna crônica, natimorto, gestação gemelar e malformação fetal. A análise estatística inclui o teste qui-quadrado, o teste "t" de Student para amostras independentes e análise múltipla por regressão logística. A porcentagem de recém-nascidos pequenos para a idade gestacional foi significativamente maior entre adolescentes multíparas (7,3%) do que entre adultas multíparas (3,6%), sendo que as únicas variáveis significativamente associadas ao risco para recém-nascidos pequenos para a idade gestacional foram idade materna -<9 anos e pequeno número de consultas pré-natais (Odds ratio=2,119 e Odds Ratio=0,311). Adolescentes multíparas apresentaram desempenho obstétrico e perinatal semelhante às adolescentes primíparas e adultas multíparas, exeto pela frequência de recém-nascidos pequenos para a idade gestacional, que foi significativamente maior entre adolescentes multíparas quando comparadas com adultas multíparas. A idade materna -<9 anso e o pequeno número de consultas pré-natal foram as únicas variáveis associadas ao risco para recém-nascidos pequenos para idade gestacional.