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An Acad Bras Cienc ; 86(3): 1295-302, 2014 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-25014916

RESUMEN

The phytochemical profile and antimicrobial activity of cultivar (cv.) extracts of Lotus uliginosus (cvs. Trojan and Serrano), L. tenuis (cv. Larrañaga) and L. corniculatus (cv. São Gabriel) were investigated. The phytochemical analysis revealed tannins, coumarins and flavonoids in all extracts, with variations among cultivars, showing genotypic variability. By High Performance Liquid Chromatographic method, the cvs. Larrañaga and São Gabriel showed the highest percentage of catechin and epicatechin, respectively, and presented rutin, which was not detected in the other ones. These genotypes showed antifungal activity but not antibacterial one. The cv. Larrañaga inhibited the mycelia growth of Alternaria sp. and Fusarium graminearum while the cv. São Gabriel was active only against Alternaria sp. The cultivars showed the greatest amounts of secondary metabolites and demonstrated significant activity against filamentous fungi. The results provide a direction for further research about pharmacological use of Lotus spp.


Asunto(s)
Antibacterianos/farmacología , Antifúngicos/farmacología , Lotus/química , Extractos Vegetales/química , Alternaria/efectos de los fármacos , Antibacterianos/química , Antifúngicos/química , Candida/efectos de los fármacos , Cromatografía Líquida de Alta Presión , Cumarinas/aislamiento & purificación , Cumarinas/farmacología , Flavonoides/química , Flavonoides/farmacología , Fusarium/efectos de los fármacos , Genotipo , Bacterias Gramnegativas/efectos de los fármacos , Bacterias Grampositivas/efectos de los fármacos , Lotus/clasificación , Lotus/genética , Extractos Vegetales/farmacología , Taninos/aislamiento & purificación , Taninos/farmacología
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