Emergence of plasmid-mediated colistin resistance and New Delhi metallo-ß-lactamase genes in extensively drug-resistant Escherichia coli isolated from a patient in Thailand.

We reported a case of Escherichia coli with colistin resistance and an extensively drug-resistant phenotype. Molecular analysis revealed that the isolate carried mcr-1 and multiple ß-lactamase genes includingblaNDM1, blaCTX-M-15, blaTEM1, and blaCMY-2. This is the first report of a clinical mcr-1 isolate in Thailand highlighting the urgent need for a comprehensive antimicrobial resistance containment strategy to prevent further spread.