Three-Year Outcomes of Biodegradable Polymer-Coated Ultra-Thin (60 µm) Sirolimus-Eluting Stents in Real-World Clinical Practice.

INTRODUCTION: Although drug-eluting stents (DES) have outclassed the use of bare metal stents, the safety and efficacy of DES at long-term follow-up has still been conflicting because of increased occurrence of late or very late restenosis and stent thrombosis after DES implantation. Hence, the present study was aimed to evaluate the 3-year safety and clinical performance of biodegradable polymer-coated ultra-thin (60 µm) sirolimus-eluting stent (SES) in real-world patients with coronary artery disease (CAD). MATERIALS AND METHODS: This was a physician-initiated, retrospective, single-centre, observational study that included 237 consecutive patients who had previously undergone implantation of only Supraflex SES (Sahajanand Medical Technologies Pvt Ltd, Surat, India) for the treatment of CAD. Follow-up was received after 1 year and 3 years of stent implantation. The primary endpoint was major adverse cardiac events (MACE), a composite of cardiac death, myocardial infarction (MI) and target lesion revascularisation (TLR). Stent thrombosis was considered as a safety endpoint. RESULTS: The mean age of patients was 64.1 ± 10.2 years, and 192 (81.0%) patients were male. The average stent length and diameter were 24.4 ± 9.0 mm and 3.1 ± 0.4 mm, respectively. The cumulative MACE rate at 3 years follow-up was 6.5% which included 4 (1.8%) cardiac deaths, 6 (2.8%) MI, and 4 (1.8%) TLR. There were 2 (0.9%) cases of stent thrombosis. CONCLUSION: Treatment of patients with CAD in real-world clinical practice was associated with sustained clinical safety and low rates of restenosis, stent thrombosis and MACE up to 3 years after Supraflex SES implantation.

Unusual presentation of squamous cell carcinoma in young female patient: A case report and review of literature.

Oral squamous cell carcinoma is the most common "malignant neoplasm" of epithelial origin usually affecting individuals over 50 years of age. It is rare in patients aged <40 years old. This report describes a case of squamous cell carcinoma involving anterior mandibular alveolar region in a 17-year-old female patient, with no history of deleterious habits. This report focuses on etiological factors, diagnosis and prognosis related to the case.

Three Dimensional CT Reconstruction for the Evaluation and Surgical Planning of Mid Face Fractures: A 100 Case Study.

BACKGROUND: 3D CT reconstruction is increasingly becoming a valuable tool in maxillofacial trauma. The aim of this study is to evaluate the role of three dimensional computed tomography as compare to conventional radiography in diagnosis and management of mid face fractures. METHODS: Hundred patients of mid face fractures were included in this study. After clinical examination patients were subjected to conventional radiographs. To arrive at correct diagnosis and treatment plan, each patient was subjected to 3D reconstruction. RESULTS: Out of hundred patients of maxillofacial trauma 80% were male and 20% were females. Based on the etiology road traffic accidents (75%) were the most common, followed by assault (16%), fall (7%) and sports related accidents (2%). In 28 cases (28%) 3D CT had significant bearing in final diagnosis and treatment planning of mid face fractures. CONCLUSIONS: 3D CT is valuable in case of severe facial injury, enabling a clear perception of extent of major fracture line and resulting displacement of fragments. So this new modality permits preoperative analysis and surgical planning as compared to conventional radiography in case of mid face fractures.