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1.
Toxicon ; 238: 107565, 2024 Feb 01.
Artículo en Inglés | MEDLINE | ID: mdl-38159684

RESUMEN

Numb chin syndrome is a rare pain disorder characterized by decreased sensation and paresthesia in the territory of the mental nerve. Neuropathic pain is sometimes described in this setting, and the most common treatments include oral analgesics, gabapentinoids, and carbamazepine; however, botulinum toxin type A has never been used in this setting. We describe a case of bilateral numb chin syndrome, secondary to Burkitt lymphoma, associated with refractory and persistent burning neuropathic pain, effectively treated twelve times with subcutaneous Botulinum toxin type A (BoNT/A) injections. The procedure was well tolerated, but the patient reported incomplete mouth closure of minimal entity. BoNT/A could be a safe and effective therapy for neuropathic pain associated with numb chin syndrome.


Asunto(s)
Toxinas Botulínicas Tipo A , Linfoma de Burkitt , Neuralgia , Humanos , Toxinas Botulínicas Tipo A/uso terapéutico , Mentón/inervación , Neuralgia/tratamiento farmacológico , Linfoma de Burkitt/complicaciones , Parestesia/complicaciones
2.
Front Neurol ; 14: 1228098, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-37465764

RESUMEN

Genitofemoral neuralgia is an uncommon pain disorder that could be resistant to conventional treatment. A 78-year-old woman with refractory right genitofemoral neuralgia was treated with BoNT/A subcutaneous injections; the treatment was performed three times with significant pain improvement, although temporary, and without adverse events. BoNT/A may be a promising alternative intervention in the setting of genitofemoral neuralgia refractory to oral and/or topical treatment.

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