The dose response of granulocyte-macrophage colony stimulating activity (GM-CSA) for sera of "Swiss" mice after endotoxin "lipopolysaccharide B" Escherichia coli (0127: B8) intraperitoneal administration.

The effect of different doses of endotoxin (Lipopolysaccharide B) on Granulocyte-Macrophage Colony Stimulating Activity (GM-CSA) in the sera of "Swiss" male mice was measured by granulocyte-macrophage "in vitro" colony formation. The highest GM-CSA was found to be present 3-4 hours after 200 micrograms of endotoxin intraperitoneal injection.