Analysis of Choroidal Vascularity in Children with Unilateral Hyperopic Amblyopia.

This institutional case control study was carried out to compare choroidal vascularity (CV) in amblyopic eyes, fellow eyes, and control eyes in children with unilateral hyperopic amblyopia. Sixty-four eyes of 32 childeren with unilateral anisometropic hyperopic amblyopia and 38 eyes of 19 healthy children (controls), aged 3 to 16 years. Subfoveal choroidal thickness (CT) and CV were measured using spectral domain optical coherence tomography. The mean subfoveal CT of amblyopic eyes (338.9 ± 60.0 µm) was greater than that of fellow eyes (315.3 ± 63.3 µm, P = 0.043) and control eyes (313.0 ± 42.1 µm, P = 0.025). The mean CV of amblyopic eyes (0.715 ± 0.020) was greater than that of control eyes (0.700 ± 0.020, P < 0.001). While a positive correlation between CT and CV was found in normal eyes (r = 0.470, P = 0.004), a strong negative correlation existed in amblyopic eyes (r = -0.684, P < 0.001). In conclusion, although mean CV was higher in amblyopic eyes, the negative correlation between CT and CV may suggests insufficient blood supply to the outer retina and choroid in the affected eyes of patients with unilateral anisometropic hyperopic amblyopia.

Surgical Feasibility of Curtler-Beard Reconstruction for Large Upper Eyelid Defect.

PURPOSE: To report long-term surgical outcomes of Cutler-Beard reconstructive surgery in patients with large full-thickness upper eyelid defects following malignant tumor excision. METHODS: The medical records of 5 consecutive patients with full-thickness upper eyelid defects following tumor resection who underwent Cutler-Beard surgery were reviewed retrospectively between April 2005 and November 2018. Surgical procedure comprises 2 stages: first, complete tumor resection followed by bridged full-thickness lower eyelid advancement flap; second, separation of the closed eyelid with eyelid margin repair 7 to 9 weeks later. Postoperative anatomical, functional and cosmetic outcomes, and complications were evaluated during follow-up at 22 to 77 months. RESULTS: Patients were in the age group of 49 to 75 years, including 3 (60%) females and 2 (40%) males. Three of the 5 patients (60%) exhibited sebaceous cell carcinoma and 2 (40%) showed squamous cell carcinoma. Three patients (60%) underwent Cutler-Beard surgery after recurrence of primary carcinoma following previous operation. Three patients underwent revision surgery with entropion, 2 underwent correction for wound dehiscence and 1 was treated with symblepharon lysis. No serious or permanent ocular complications were observed during the operation or follow-up with the patients. The procedure resulted in good aesthetic quality and acceptable sequelae at the donor site. CONCLUSIONS: Cutler-Beard procedure for the reconstruction of large and full-thickness upper eyelid defects is an effective procedure with satisfactory long-term results, although a few patients may require minor revision surgery.