RESUMEN
BACKGROUND: Smooth muscle tumors of the vulva are rare and sometimes create diagnostic difficulty because of unusual morphological features. CASE: A 29-year-old African-American female presented with a vulval mass during her 5th week of pregnancy. The lesion was surgically removed under the clinical impression of a Bartholin cyst. Histopathological findings of the lesion and immunohistochemical stain results are characteristic of myxoid epithelioid leiomyoma. CONCLUSION: Up to now, there are only a few cases of myxoid epithelioid leiomyoma of the vulva reported in English literature. We review previously reported cases and discuss the morphologic differential diagnosis. The mass presented in this report was the largest benign epithelioid leiomyoma in the literature.
Asunto(s)
Leiomioma Epitelioide/patología , Neoplasias de la Vulva/patología , Adulto , Femenino , Humanos , Leiomioma Epitelioide/cirugía , Neoplasias de la Vulva/cirugíaRESUMEN
We report a case of gallbladder paraganglioma that was discovered during nonrelated surgery. Retrospective study disclosed a family history of pheochromocytoma. The occurrence of gallbladder paraganglioma in the presence of family history of endocrine neoplasia supports that gallbladder paraganglioma may indeed occur as a part of the multiple endocrine neoplasm syndrome. Gallbladder paraganglioma is a rare tumor, and so far to our knowledge only 6 cases have been reported in the literature. Three cases were discovered incidentally during cholecystectomy for cholelithiasis, 2 presented with right upper quadrant pain, and 1 manifested with gastrointestinal bleeding. We herein review all reported cases of paraganglioma of gallbladder and biliary system.
Asunto(s)
Neoplasias de la Vesícula Biliar/patología , Neoplasia Endocrina Múltiple/patología , Paraganglioma/patología , Adulto , Humanos , Hallazgos Incidentales , MasculinoRESUMEN
We report a case of an adenomatoid tumor (AT) of an adrenal gland with micronodular adrenal cortical hyperplasia (ACH). A 51-year-old man was found to have newly developed hypertension with clinical evidence of primary aldosteronism. A computerized tomogram of the abdomen revealed a solitary mass in the right adrenal gland. He underwent a right adrenalectomy for a presumptive clinical diagnosis of a solitary aldosterone-producing adrenal cortical adenoma. On histopathologic examination, the adrenal gland demonstrated an AT, diagnosed by the characteristic histological features, immunohistochemical stain results, and electron microscopic findings. The surrounding adrenal cortex showed multiple small hyperplastic cortical nodules. After the adrenalectomy, the patient's blood pressure normalized. Primary AT of the adrenal gland coexisting with micronodular ACH associated with hypertension has not been previously reported.
Asunto(s)
Neoplasias de la Corteza Suprarrenal/patología , Adenoma Corticosuprarrenal/patología , Hiperaldosteronismo/patología , Neoplasias de la Corteza Suprarrenal/complicaciones , Neoplasias de la Corteza Suprarrenal/cirugía , Adenoma Corticosuprarrenal/complicaciones , Adenoma Corticosuprarrenal/cirugía , Humanos , Hiperaldosteronismo/etiología , Hiperaldosteronismo/cirugía , Hiperplasia , Masculino , Persona de Mediana Edad , Resultado del TratamientoRESUMEN
Ectopic breast tissue has been described rarely in the vulva and is known to develop a variety of pathologic changes. Our review of the literature found a total of 11 reported cases of primary infiltrating ductal adenocarcinoma arising in ectopic breast tissue of the vulva. We report what we believe is the first case of primary mucinous adenocarcinoma arising in ectopic breast tissue of the vulva diagnosed by characteristic histopathologic features and immunohistochemical stain results. We discuss the criteria used in diagnosis of primary breast carcinoma of the vulva and review previously reported cases.