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1.
Artículo en Chino | WPRIM (Pacífico Occidental) | ID: wpr-1017726

RESUMEN

Airway mucus hypersecretion is one of the pathological changes in children with community acquired pneumonia(CAP),and affects the severity,progression and prognosis of CAP.Diagnosis of airway mucus hypersecretion currently relies on fiberoptic bronchoscopy. To predict the risk of airway mucus hypersecretion and to take early action to avoid serious consequences such as plastic bronchitis and hypoxia and respiratory failure,the article summarizes the relationship between age,clinical characteristics and laboratory indices and the formation of airway mucus hypersecretion in children with CAP. Among them,age,pathogenic species,fever peak and fever range,neutrophil ratio,C-reactive protein,lactate dehydrogenase,D-dimer,serum 25(OH)D,and some interleukins,interferons,and acquired immune indicators have an early warning effect on the development of airway mucus hypersecretion in children with CAP.

2.
J Agric Food Chem ; 67(31): 8476-8484, 2019 Aug 07.
Artículo en Inglés | MEDLINE | ID: mdl-31298527

RESUMEN

Cicada flowers, which are edible and medicinal mushrooms, are the fruiting bodies of Isaria cicadae, a fungus that is parasitic on the larvae of cicada pupae. We hypothesize that host factors might possess stimulatory activity on metabolite synthesis in Isaria cicadae. Here, we first compared the microbial community structures of different wild cicada flowers across geographical regions, compartments, and growth stages via high-throughput sequencing. Isaria cicadae TZC-3, an isolate of the most abundant operational taxonomic unit (OTU6782) in all the fungal communities, was isolated from wild cicada flowers. Furthermore, the effects of cicada pupae on metabolite synthesis in Isaria cicadae TZC-3 were studied in submerged culture. The contents of intercellular polysaccharides, adenosine, N6-(2-hydroxyethyl)-adenosine, free amino acids, and hydrolyzed monosaccharides in the mycelia cultured with cicada pupa powder (4%) were significantly increased as compared with the contents in the control group. This indicates that a cicada pupa can act as an elicitor for metabolite synthesis in Isaria cicadae.


Asunto(s)
Cordyceps/metabolismo , Cuerpos Fructíferos de los Hongos/química , Hemípteros/microbiología , Pupa/microbiología , Adenosina/análisis , Adenosina/metabolismo , Aminoácidos/análisis , Aminoácidos/metabolismo , Animales , Cordyceps/química , Cordyceps/crecimiento & desarrollo , Cuerpos Fructíferos de los Hongos/crecimiento & desarrollo , Cuerpos Fructíferos de los Hongos/metabolismo , Hemípteros/química , Hemípteros/metabolismo , Interacciones Huésped-Patógeno , Microbiota , Micelio/química , Micelio/crecimiento & desarrollo , Micelio/metabolismo , Pupa/química , Pupa/metabolismo
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