Imagen multimodal no invasiva en rotura coroidea secundaria a explosión de petardo / Multimodal non-invasive imaging in choroidal rupture secondary to a firework explosión

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Miopía, el reto de la Oftalmología y su "explosiva epidemia" mundial / Myopia, the challenge of Ophthalmology and its worldwide "explosive epidemic"

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Retinopatía asociada a ocriplasmina: posible causa de fracaso de cierre de agujero macular / Ocriplasmin retinopathy: Possible cause of macular hole closure failure

CASO CLÍNICO: Mujer de 53 años con agujero macular estadio 2, que recibió como primera opción terapéutica una inyección de ocriplasmina, pero a la que se le tuvo que practicar vitrectomía pars plana por aumento del agujero macular postinyección. La ganancia visual tras la cirugía fue mínima a pesar del cierre del agujero, lo que podría explicarse por la atrofia retiniana externa como consecuencia de los potenciales mecanismos tóxicos asociados a ocriplasmina. Discusión: Son necesarios más estudios para entender el completo impacto de la ocriplasmina en la función visual a largo plazo

CASE REPORT: A 53 year-old woman with a stage 2 macular hole received ocriplasmin injection as a first approach. She subsequently underwent pars plana vitrectomy due to enlargement of the hole post-injection. The visual gain following the surgery was minimal despite closure of the hole. This could be explained by outer retina atrophy as a consequence of potential toxic mechanisms related to ocriplasmin. DISCUSSION: Further studies may be warranted to fully understand the impact of ocriplasmin on long-term visual function

Ocriplasmin retinopathy: Possible cause of macular hole closure failure. / Retinopatía asociada a ocriplasmina: posible causa de fracaso de cierre de agujero macular.

CASE REPORT: A 53 year-old woman with a stage 2 macular hole received ocriplasmin injection as a first approach. She subsequently underwent pars plana vitrectomy due to enlargement of the hole post-injection. The visual gain following the surgery was minimal despite closure of the hole. This could be explained by outer retina atrophy as a consequence of potential toxic mechanisms related to ocriplasmin. DISCUSSION: Further studies may be warranted to fully understand the impact of ocriplasmin on long-term visual function.

Grosor coroideo subfoveal medido con tomografía de coherencia óptica swept source en ojos con edema macular diabético / Subfoveal choroidal thickness in eyes with diabetic macular oedema using swept source optical coherence tomography

PROPÓSITO: Comparar el grosor coroideo subfoveal (GCSF) entre pacientes con edema macular diabético (EMD) y sujetos sanos mediante tomografía de coherencia óptica swept source (SS-OCT). MÉTODO: Estudio transversal con 50 ojos de 36 pacientes con EMD y 47 ojos de 34 pacientes como grupo control. Fue evaluado el GCSF en ambos grupos, realizándose además un análisis entre los ojos con EMD en función del tipo de edema (predominantemente quístico o difuso). RESULTADOS: Los grupos de estudio fueron homogéneos en cuanto a la edad media (63,4 años para EMD y 62,65 años para controles; p = 0,36) y la longitud axial media (23,21 mm para EMD y 23,53 mm para controles; p = 0,06). Se objetivó una reducción estadísticamente significativa en el grosor coroideo entre los ojos con EMD respecto al grupo control (192,82 vs. 222,9 μm; p = 0,041). No se evidenciaron diferencias estadísticamente significativas en los ojos con EMD en función del patrón de edema predominantemente quístico y difuso (205,7 vs. 178,68 μm; p = 0,13). CONCLUSIÓN: El GCSF en pacientes con EMD podría encontrarse reducido, sin que el patrón de engrosamiento macular tomográfico se asocie a diferencias significativas en este sentido. Son necesarios futuros estudios para confirmar estos resultados preliminares

PURPOSE: To compare subfoveal choroidal thickness (GCSF) in patients with diabetic macular oedema (DMO) and healthy subjects using swept source optical coherence tomography (SS-OCT). METHOD: Cross-sectional study including 50 eyes of 36 patients with DMO, and 47 eyes of 34 patients as a control group. GCSF was measured in both groups, analysing between the eyes with DMO according to the type of oedema (predominantly cystic or diffuse). RESULTS: The study groups were homogeneous in terms of mean age (63.4 years for DMO and 62.65 years for controls; P=.36) and the mean axial length (23.21 mm for DME and 23.53 mm for controls; P=.06). A statistically significant reduction in the eye with DME GCSF compared to controls (P=.041, 222.9 vs. 192.82 μm) was observed. No statistically significant differences were observed in the eyes with DMO with a predominantly cystic pattern and diffuse oedema (P=.13, 178.68 vs. 205.7 μm). CONCLUSION: The GCSF in patients with DMO could be reduced. Future studies are needed to confirm these preliminary results

Subfoveal choroidal thickness in eyes with diabetic macular oedema using swept source optical coherence tomography. / Grosor coroideo subfoveal medido con tomografía de coherencia óptica swept source en ojos con edema macular diabético.

PURPOSE: To compare subfoveal choroidal thickness (GCSF) in patients with diabetic macular oedema (DMO) and healthy subjects using swept source optical coherence tomography (SS-OCT). METHOD: Cross-sectional study including 50 eyes of 36 patients with DMO, and 47 eyes of 34 patients as a control group. GCSF was measured in both groups, analysing between the eyes with DMO according to the type of oedema (predominantly cystic or diffuse). RESULTS: The study groups were homogeneous in terms of mean age (63.4 years for DMO and 62.65 years for controls; P=.36) and the mean axial length (23.21mm for DME and 23.53mm for controls; P=.06). A statistically significant reduction in the eye with DME GCSF compared to controls (P=.041, 222.9 vs. 192.82 µm) was observed. No statistically significant differences were observed in the eyes with DMO with a predominantly cystic pattern and diffuse oedema (P=.13, 178.68 vs. 205.7 µm). CONCLUSION: The GCSF in patients with DMO could be reduced. Future studies are needed to confirm these preliminary results.

Propranolol e inyecciones intravítreas de ranibizumab en el desprendimiento seroso macular secundario a hemangioblastoma retiniano capilar / Oral propranolol and intravitreal ranibizumab for refractory serous macular detachment secondary to retinal capillary hemangioblastoma

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Estudio comparativo de la modificación de la osmolaridad en enfermedad injerto contra huésped / Comparative study of modification of the osmolarity in graft versus host disease

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Goldmann-Witmer, diagnóstico de certeza en coroiditis unifocal helioide / Goldmann-Witmer, definitive diagnosis in unifocal helicoid choroiditis

CASO CLÍNICO: Paciente sano de 20 años con pérdida de visión aguda en el ojo izquierdo. Al examen del fondo de ojo presentó una alteración macular compatible con coroiditis unifocal helioide caracterizada por ser una lesión inflamatoria atípica redondeada, solitaria, blanca-amarillenta, de aproximadamente del tamaño de un disco óptico. En el estudio etiológico se detectó leve positividad serológica de IgG (inmunoglobulinas G) Antitoxoplasma gondii. DISCUSIÓN: Una serología inespecífica y las características atípicas de la lesión limitan el diagnóstico. El coeficiente Goldmann-Witmer puede ser útil en el diagnóstico de lesiones localizadas al relacionar concentraciones entre IgG séricas y humor acuoso

CASE REPORT: A 20 year-old healthy patient consulted due to acute loss vision in his left eye. A fundus examination showed a macular alteration compatible with unifocal helioid choroiditis, characterized by being an atypical inflammatory yellow-white, round, single lesion of approximately an optic disc in diameter. The etiology study detected low Antitoxoplasma gondii Ig G (immunoglobulin) titers. DISCUSSION: The non-specificity of the serology and the atypical characteristics of the lesion is a limitation in the diagnosis. The Goldmann-Witmer coefficient may be useful in the diagnosis of atypical lesions, by comparing the concentration of IgG from the serum and aqueous humor

Láser subumbral para coriorretinopatía serosa central activa / Subthreshold laser for active central serous chorioretinopathy

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Retinopatía hipertensiva bilateral diagnóstica de feocromocitoma / Bilateral hypertensive retinopathy diagnostic of pheochromocytoma

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[Goldmann-Witmer, definitive diagnosis in unifocal helicoid choroiditis]. / Goldmann-Witmer, diagnóstico de certeza en coroiditis unifocal helioide.

CASE REPORT: A 20 year-old healthy patient consulted due to acute loss vision in his left eye. A fundus examination showed a macular alteration compatible with unifocal helioid choroiditis, characterized by being an atypical inflammatory yellow-white, round, single lesion of approximately an optic disc in diameter. The etiology study detected low Antitoxoplasma gondii Ig G (immunoglobulin) titers. DISCUSSION: The non-specificity of the serology and the atypical characteristics of the lesion is a limitation in the diagnosis. The Goldmann-Witmer coefficient may be useful in the diagnosis of atypical lesions, by comparing the concentration of IgG from the serum and aqueous humor.

Hydrophilic acrylic intraocular lens clouding: a clinicopathological review.

PURPOSE: An analysis is made of a serious late complication (opacification) of different models of hydrophilic acrylic intraocular lenses (IOLs). METHODS: Seven lenses were explanted from seven patients treated for cataracts with phacoemulsification and implantation of different types of hydrophilic acrylic IOLs (five SC60B-OUV from MDR, one Aquasense from OII, and one H60M Hydroview lens from Bausch & Lomb) who developed important vision impairment in the late postoperative period (1 to 3 years) due to lens opacification. The explanted lenses were subjected to exhaustive study involving photographic analysis, scanning electron microscopy, and energy dispersive X-ray spectroscopy. RESULTS: Light and scanning electron microscopy revealed diffuse, variable-size granular deposits within the optic of the SC60B-OUV lens, and on the anterior and posterior optic surfaces of the H60M Hydroview lens, though without affecting the haptics in any of the models. Dispersive energy X-ray spectroscopy of the deposits revealed the presence mainly of calcium and phosphorus salts. CONCLUSIONS: Hydrophilic acrylic IOL opacification is a serious late complication of unknown etiology. The condition is more frequent among diabetic patients, and the only management option is IOL explantation and replacement with a lens of some other material. More frequent and longer follow-up is required of those patients wearing lenses for which cases of opacification have been documented, particularly in the presence of predisposing factors (diabetes, uveitis). Caution is required with new lenses, avoiding their generalized use until they have successfully passed the test of time.