Correction: CT-Angiographic Aspects of Pulmonary Embolism on SARS COV-2.

[This corrects the article DOI: 10.5334/jbsr.3021.].

CT-Angiographic Aspects of Pulmonary Embolism on SARS COV-2.

Objectives: To study pulmonary embolism during COVID-19 pneumonia. Patients and Methods: This was a one-year retrospective and descriptive study of all patients from three imaging sites with SARS-CoV2 infection. Results: Two hundred and thirty-nine patients were included. The prevalence of pulmonary embolism was 18.4%. The average age was 55 years old. The sex ratio was 1.65. Dyspnea (58.6%), cough (56.1%), and chest pain (40.2%) were the most common reasons for consultation. In 151 patients (63.2%), chest computed tomography (CT) angiography was performed without checking level of D-dimer. The level of D-dimers was elevated in 47.8%. Grade 5 of CO-RADS accounted for 62.3%. In 70.5% of cases, the pulmonary embolism was bilateral with subsegmental involvement in 47.7%.Condensation in 'ground glass' with 'crazy paving' were the predominant typical parenchymal lesions with a frequency of 93.7% and 59.4%. In univariate analysis, D-dimers were significantly associated with the occurrence of pulmonary embolism (p < 0.001). Male sex was associated with a non-significantly higher Risk of having a pulmonary embolism (1.18 95% CI: 0.61-2.31, p = 0.622). The critical level increased the risk of pulmonary embolism in a non-significant way. Only the high level of D-dimers was and this, in a significant way. Conclusion: Pulmonary embolism was increased in the context of SARS-CoV2. The chest CT-angiography associated with the dosage of D-dimers constitutes a good diagnostic arsenal.

Aspects scanographiques de la pneumopathie à COVID-19 à Ouagadougou: Étude multicentrique à propos de 1017 cas.

OBJECTIVE: To study the chest CT profile of SARS-CoV-2 pneumonia in patients in the city of Ouagadougou. PATIENTS AND METHODS: descriptive cross-sectional study with retrospective collection of 1017 patients of both sexes. Included were patients aged 15 and over who had performed a chest CT scan without or with injection of contrast product, suspected or positive for COVID -19. The variables analyzed were: the history, the nature of the examination, the socio-demographic, clinical, CT data including the description of the tomodensitometric lesions and their characteristics, the extent of the parenchymal lesions according to the visual estimate of the French thoracic Imaging Society, complications, other lesions on the chest CT scan and CORADS classification. All parameters (age, sex on the one hand and clinical and CT findings on the other) were subjected to statistical analysis. RESULTS: The mean age of the patients was 56.95 years, predominantly male (1.47). Dyspnea was the most frequent symptomatology, at 46.26% (n = 506). Diabetes was the most common comorbidity with 29.37% (n = 94). Frosted glass opacity accounted for 90.95% of elementary lesions which were predominantly in plaque in 44.35% (n = 451), bilateral in (82.79%) and peripheral subpleural in (81.51%). The lower lobes were the most affected and postero-basal involvement predominant with greater involvement in the right lung. The extent was severe in 28.42% (n = 289). Thirty-nine point twenty-three (39.23)% or 399 of cases presented with complications dominated by pleural effusion at 56.39% (n = 225) and pulmonary embolism at 34.08% (n = 136 ). The lesions were classified as CORADS type in 815 CT reports. CORADS 5 type lesions were found in 47% of patients. Five hundred and ninety-two (592) PCRs of our patients were undetermined, in 58.21%. The PCR was positive in 342 cases or 33.63%. The bi- and multivariate analysis noted: a statistically significant link between the age and the extent of the lesions, between the extent of the lesions and the clinical context, between the extent of the lesions and comorbidities such as diabetes, Hypertension and renal failure. There was also a link between the PCR result and basic lesions such as ground glass and crazy paving and between the occurrence of pulmonary embolism and the presence of hypertension. DISCUSSION: The scanographic profile corresponded to that described in the literature. Frosted glass was the most common elementary lesion. The impairment was severe to critical in patients over 65 with comorbidity. CT angiography was the most requested in front of signs such as dyspnea and desaturation CONCLUSION: A study on CT specificities with precision on the onset of symptoms and the notion of vaccination would complement these results.

Aortic dissection-Pulmonary embolism association: A therapeutic dilemma.

Aortic dissection is a rare but serious condition. Its association with pulmonary embolism is exceptional and produces a real therapeutic dilemma. We are discussing the case of a 67-year-old male patient who presented with paraplegia with infectious syndrome. The chest X-ray performed to screen for an infectious site led to the suspicion of an aortic aneurysm and the CT angiography showed Stanford type B aortic dissection associated with bilateral proximal pulmonary embolism. The treatment was symptomatic and resulted in the patient's death 48 hours after diagnosis. Management of this pathological association is not standardized between establishing anticoagulant therapy and therapeutic abstention. This management depends on the teams and has a very cautious prognosis.

[Status of obstetrical echography at the imaging service of the University Hospital Center of Bogodogo from January 1st, 2016 to December 31st, 2018]. / État des lieux des échographies obstétricales au service d'imagerie du Centre Hospitalier Universitaire Bogodogo du 1er janvier 2016 au 31 décembre 2018.

Obstetric ultrasound performed according to standards from its prescription to the report is a guarantee of quality. The aim of our study was to take stock of obstetrical ultrasounds in order to make rational the ultrasound follow-ups of pregnancy. This was a descriptive cross-sectional study with retrospective data collection through the reports of obstetrical ultrasounds performed from the 1st January 2016 to 31st December 2018. Of the 13,487 ultrasounds in the study period, 2,355 were obstetric ultrasounds, constituting 1746% of the ultrasound activity. The mean gestational age was 27.54 years (± 6.19). The CHU Bogodogo was the requesting structure for 86.88%. Paramedics were prescribers in 66.47%. Third trimester ultrasounds made up 57.06%. Gestational age in 12.99% was greater than 37 weeks while in 66.37% gestational age was greater than 24 weeks. Prenatal follow-up was indicated in 54.48%. Pregnancies were progressive in 97.49%. Twin pregnancies represent 2.72% and ultrasound pathological pregnancies 11.80%. Obstetric Doppler was performed in 2.12% with pre-eclampsia as the main indication (52%). There was 1.18% malformation with nervous system involvement in 60.71%. Through this inventory, the training of prescribers of obstetric ultrasound appears essential. The establishment of an observatory of obstetric ultrasound practices would be an asset for the quality of these medical examinations.

Ectopic pheochromocytoma or paraganglioma of the ZUCKERKANDL organ: A case report and review of the literature.

INTRODUCTION: Paraganglioma of the ZUCKERKANDL organ are rare. Diagnosis is based on clinical, radiological and biological arguments. We report a case to describe our surgical procedure and insist on the necessity of preoperative diagnosis. PRESENTATION OF CASE: BA, 52-years-old male patient was seen in consultation for left hypochondrium pains. The clinical examination had revealed a painful tumefaction in the left flank and the left hypochondrium. A deep mass was observed, but was difficult to be assessed, due to pain. Abdominal-pelvic CT scan with contrast injection had revealed a tissue mass, suggesting a tumor of the tail of the pancreas. Laparotomy showed this mass was not attached to the tail of the pancreas, and was along the abdominal aorta up to the aortic bifurcation. Upon touching the mass, blood pressure raised up to 240 mmHg. A least mobilization of the mass and the use of nicardipine helped maintain blood pressure below 180mmhg. Dissection was carried out from the aortic bifurcation to the TREITZ's angle and the mass was removed. The follow-ups were characterized by low blood pressure a few minutes following the resection of the mass. DISCUSSION: Pheochromocytoma is rare. The Clinical signs, Abdominal-pelvic CT scan and biology are the steps of the preoperative diagnosis. The surgery consists a lumpectomy. The resuscitation determines the patient's prognosis. CONCLUSION: Pheochromocytoma is an unusual mass. Preoperative diagnosis can be difficult in pauci-symptomatic cases. One should consider this in the face of any abdominal mass, so as to improve planning of resuscitation which determines the patient's prognosis.

Giant lipoma of the left mesocolon: Radiological and surgical aspects.

INTRODUCTION: Abdominal masses are common in digestive surgery and gastro-enterology units. However, meso-intestinal lipomas remain rare and lipoma of the left colon uncommon. We report a case of giant lipoma of the left mesocolon whose diagnosis was highly guided by radiological examinations. PRESENTATION OF CASE: A female patient aged 56, consulted for left subcostal abdominal pains. The clinical examination showed an abdominal mass occupying the left hemiabdomen. The abdominal-pelvic CT scan highlighted a large abdominal-pelvic mass in the left abdomen. Abdominal-pelvic MRI revealed a large fatty mass spreading from the front subphrenic space up to the level of the left iliac fossa, non-suspected and compatible with lipoma. FDG-Pet Scan had not revealed pathological fixing. The mass appeared like a total gap space. Exploratory surgery revealed a lipoma mass in the left mesocolon. Hemicolectomy was performed taking away the mass. Histology confirmed the diagnosis of lipoma and the outcome was favourable. DISCUSSION: Our case represents the fourth case of mesocolon lipoma described in the literature. Imaging, especially TDM and MRI are an important step of the preoperative diagnosis. The surgery consists of either a lumpectomy or a colectomy. CONCLUSION: Lipoma of the left mesocolon is exceptional. Radiological examinations provide most arguments to suggest lipoma. However the organ's diagnosis is provided by surgical exploration and the certainty diagnosis by pathological examination. Treatment is surgical.

Anomalies associées aux holoprosencéphalies à l'échographie anténatale: à propos d'une série de 11 cas à Ouagadougou (Burkina Faso)

Objectifs : décrire les anomalies associées aux holoprosencéphalies suspectées lors de l'échographie anténatale. Patients et méthodes. Il s'est agi d'une étude transversale descriptive. Nous avons inclus de façon consécutive, les cas suspects d'holoprosencéphalies diagnostiqués au cours d'échographies anténatales évolutives réalisées dans notre centre d'imagerie, entre janvier 2016 et décembre 2018, quel que soit l'âge gestationnel. Résultats : 11 cas suspects d'holoprosencéphalies ont été identifiés. Il s'agissait de formes alobaires dans huit cas et de forme semi lobaire dans trois cas. L'âge gestationnel médian lors du diagnostic était de 31 semaines d'aménorrhée [13 et 38 ans]. L'âge maternel médian était de 32 ans [23-41ans]. Il n'y avait pas de diabète maternel ou d'antécédent familial noté chez ces patientes. Les anomalies encéphaliques à type d'absence de la ligne médiane, de ventricules unique et de fusions des thalami étaient notées chez tous les foetus. Les anomalies nasales étaient présentes dans 8 cas /11, labiales dans 2 cas/11 et oculaires dans 5 cas/11. Les foetus étaient majoritairement de type féminin. On notait la présence d'autres anomalies dans 5 cas/11. Il s'agissait de néphropathie, d'anomalie fémorale et d'une communication interventriculaire. Conclusion : Malformation rare, l'holoprosencéphalie est diagnostiquée tardivement dans notre contexte. Il n'y avait pas de facteur étiopathogénique retrouvé. Les tests génétiques et l'étude du caryotype n'étaient pas disponibles dans notre contexte au cours de l'étude

Profil mammo-échographique et histopathologique des cancers du sein de la femme à Ouagadougou (Burkina Faso)

Objectif : Décrire les aspects radiologiques et histopathologiques des tumeurs malignes mammaires chez la femme au Burkina Faso. Matériels et méthodes : étude transversale analytique à collecte rétrospective réalisée de janvier 2014 à octobre 2017. Les patientes incluses ont eu une microbiopsie mammaire sous guidage échographique après une exploration mammographique et échographique, avec un résultat histopathologique de malignité. Les variables recueillies étaient l'âge, les antécédents, la taille des nodules, la classification ACR et le diagnostic anatomopathologique. Résultats : l'échantillon de lésions malignes étaient constitué de 173 nodules. L'âge moyen était de 49.15 ± 11.55 ans et la taille moyenne des lésions de 31.57 ± 18.21mm. Les femmes de moins de 40 ans représentaient 16,8% de l'échantillon. Les antécédents familiaux étaient connus dans 7% des cas. A l'imagerie, on notait 4,05% de lésions classées ACR3, 68,79% de lésions ACR4 et 27,17% de nodules ACR5. Les tumeurs malignes étaient constituées essentiellement de carcinomes canalaires infiltrants dans 98,26 %. Conclusion. Le cancer du sein est mis en évidence chez la femme de la cinquantaine. Les nodules ont une tendance à la bénignité chez les femmes jeunes. La taille moyenne de la lésion est importante au moment du diagnostic

Right upper pulmonary vein metastasis from hepatocarcinoma.

Metastatic tumor involvement of the heart is uncommon but may occur with all types of primary neoplasms. We report the case of a 51-year-old male who developed a massive mass involving the upper right pulmonary vein. The tumor was removed and the final pathology report disclosed metastatic hepatocellular carcinoma. Hepatocellular carcinoma affecting the pulmonary veins is a very rare condition.

Effectiveness of a community-based educational programme in reducing the cumulative incidence and prevalence of human Taenia solium cysticercosis in Burkina Faso in 2011-14 (EFECAB): a cluster-randomised controlled trial.

BACKGROUND: The effectiveness of drug-free interventions in controlling human cysticercosis is not well known. We aimed to estimate the effectiveness of a community-based educational intervention in reducing the frequency of human cysticercosis in Burkina Faso. METHODS: We did a cluster-randomised controlled trial between 2011 and 2014. 60 eligible villages from three provinces (Boulkiemdé, Sanguié, and Nayala) were randomly allocated to the intervention or control group. Villages raising pigs, that were not a regional capital or located on a main road, that were more than 20 km from Ouagadougou or 5 km from one another, were eligible. In each village, 60 participants were asked for blood samples at baseline, 18 months later (before randomisation), and 18 months after randomisation. Villages were block randomised (1:1) by pig-raising department immediately after the pre-randomisation visit. The intervention aimed to improve knowledge of Taenia solium transmission and control through screening and structured discussion of a 52-min movie, and to increase community self-efficacy through a Self-esteem, Associative strengths, Resourcefulness, Action planning, Responsibility (SARAR) approach via the Participatory Hygiene and Sanitation Transformation (PHAST) model. The primary outcome was active cysticercosis, defined as the presence of circulating antigens detected by use of B158/B60 ELISA. Effectiveness measured at the village level was estimated by use of three Bayesian hierarchical models. This study is registered with ClinicalTrials.gov, number NCT0309339. FINDINGS: Two villages in the same randomisation block were excluded, resulting in a final sample size of 58 villages. Overall, the intervention tended towards a decrease in the cumulative incidence of active cysticercosis from baseline to after randomisation (adjusted cumulative incidence ratio 0·65, 95% Bayesian credible interval [95% CrI] 0·39-1·05) and a decrease in active cysticercosis prevalence from baseline to after randomisation (adjusted prevalence proportion ratio 0·84; 95% CrI 0·59-1·18). The intervention was shown to be effective in Nayala and Sanguié but not in Boulkiemdé. INTERPRETATION: Community-engaged participatory interventions can be effective at reducing the incidence and prevalence of cysticercosis in some low-resource settings. FUNDING: US National Institutes of Health (National Institute of Neurological Disorders and Stroke, Fogarty International Center, and National Institute of General Medical Sciences).

Evaluating the Recombinant T24H Enzyme-Linked Immunoelectrotransfer Blot Assay for the Diagnosis of Neurocysticercosis in a Panel of Samples from a Large Community-Based Randomized Control Trial in 60 Villages in Burkina Faso.

Current guidelines for the diagnosis of neurocysticercosis (NCC) recommend the use of the lentil lectin-bound glycoprotein enzyme-linked immunoelectrotransfer blot assay (LLGP-EITB) as the reference standard for serological testing. In response to the drawbacks involved with the use of the LLGP-EITB, a recombinant T24H antigen (rT24H) EITB assay was developed, with promising results. However, the test has yet to be evaluated among individuals from sub-Saharan Africa (SSA). The aim of the present study was to investigate the performance of the rT24H EITB assay for the detection of NCC cases in a panel of serum samples (N = 366, of which 173 patients presented with epileptic seizures and/or severe chronic headaches, and 193 matched manifestation-free participants) collected as part of a large community-based trial in Burkina Faso. A perfect agreement between the rT24H EITB and the native gp24 (and its homodimer, gp42) LLGP-EITB was found (kappa value of 1.0). Furthermore, among patients with the neurological manifestations of interest who underwent a computed tomography scan, the rT24H EITB and native antigen LLGP-EITB had a comparable ability to correctly identify NCC cases with multiple viable (rT24H: sensitivity: 80.0%), single viable (66.7%), and calcified/degenerating cysts only (25.0%), albeit for multiple viable and calcified cysts, the rT24H estimated sensitivity seemed lower, but more uncertain, than previously reported. The rT24H EITB specificity was high (98.2%) and in line with previous studies. This study confirms the value of the recombinant rT24H EITB as an alternative to the native antigen LLGP-EITB for the diagnosis of NCC in a SSA community setting.

Évaluation des connaissances des praticiens sur la radioprotection des patients au Burkina Faso

Objectif : Évaluer les connaissances des praticiens sur la radioprotection des patients au Burkina Faso.Méthodes : Étude descriptive transversale multisites du 1er mars au 31 mai 2015 dans trois structures sanitaires auprès des prescripteurs chez qui un questionnaire comportant plusieurs items en rapport avec les connaissances sur la radioprotection a été administré.Résultats : Le questionnaire a été soumis à 164 médecins : 123 (75%) ont accepté de le remplir ; 82,9% prenaient en compte le rapport bénéfice-risque ; 60% informaient le patient sur les risques des rayonnements ionisants ; 26,9% avaient une bonne connaissance sur les objectifs de la radioprotection et 17,9% sur les principes de la radioprotection ; 83,7% étaient informée de l'existence du risque de cancer radio-induit ; 80% reconnaissaient l'exposition médicale comme source d'irradiation et 36,6% considéraient l'IRM comme une technique irradiante. Conclusion : Notre étude a montré une faible connaissance des principes, des objectifs de la radioprotection par les praticiens bien que l'existence du risque de cancer radio-induit lors de la réalisation de certains examens radiologiques n'était pas ignorée

La ponction biopsie hépatique écho-guidée en ambulatoire à Ouagadougou : indications, apport diagnostique et complications

Objectif : Déterminer l'apport diagnostique de la ponction biopsie hépatique par voie per cutanée sous guidage échographique.Matériel et méthodes : étude rétrospective descriptive réalisée de mars 2013 à mars 2017. Ont été inclus tous les patients ayant bénéficié d'une biopsie hépatique sous guidage échographique. Les variables recueillies ont été le sexe, l'âge, l'indication, le nombre de carottes biopsiques, les complications et le diagnostic anatomopathologique.Résultats. 53 patients ont été colligés. Il y avait 37 hommes (69,81%) et 16 femmes (30,18 %) soit un sex ratio de 2,31. L'âge moyen était de 45,79 ans avec des extrêmes de 15 et de 82 ans. Les indications étaient principalement représentées par l'exploration des nodules dans 49 cas (92,24%) et des hépatopathies chroniques dans 4 cas (7,76%). Le diagnostic anatomopathologique était essentiellement dominé par le CHC dans 33 cas (63,46%). Une douleur modérée passagère, était notée chez 37,73% des patients au passage de la capsule. Aucune complication majeure n'était retrouvée.Conclusion. La réalisation des PBH sous guidage échographique était fiable et réalisable en ambulatoire, pour peu que le bilan d'hémostase, l'utilisation d'une prémédication et d'une aiguille fine avec un système coaxial soit respecté

Prevalence of neurocysticercosis among people with epilepsy in rural areas of Burkina Faso.

PURPOSE: To estimate the lifetime prevalence of neurocysticercosis (NCC)-associated epilepsy and the proportion of NCC among people with epilepsy in three Burkina Faso villages. METHODS: Three villages were selected to represent three types of pig-rearing methods: (1) Batondo, where pigs are left to roam; (2) Pabré, where pigs are mostly tethered or penned; and (3) Nyonyogo, where the majority of residents are Muslim and few pigs are raised. In Batondo and Nyonyogo, all concessions (a group of several households) were included. Half of the concessions in Pabré were randomly chosen. All households of selected concessions were included, and one person per household was randomly selected for epilepsy screening and serologic testing for cysticercosis. Self-reported cases of epilepsy were also examined and confirmed cases included in analyses other than the estimate of NCC-associated epilepsy prevalence. Epilepsy was defined as ever having had more than one episode of unprovoked seizures. Individuals with medically confirmed epilepsy had a computerized tomography (CT) scan of the brain before and after contrast medium injection. The diagnosis of NCC was made using a modification of the criteria of Del Brutto et al. KEY FINDINGS: Thirty-nine (4%) of 888 randomly selected villagers and 33 (94%) of 35 self-reported seizures cases were confirmed to have epilepsy by medical examination. Among the 68 participants with epilepsy who had a CT scan, 20 patients were diagnosed with definitive or probable NCC for a proportion of 46.9% (95% confidence interval [CI] 30.2-64.1) in Batondo and 45.5% (95% CI 19.0-74.1) in Pabré. No cases of NCC were identified in Nyonyogo. SIGNIFICANCE: All the definitive and probable cases of NCC were from the two villages where pig breeding is common. Prevention policies intended to reduce the burden of epilepsy in this country should include measures designed to interrupt the life cycle of Taenia solium.

[Trilateral retinoblastoma in Burkina Faso: three cases]. / Rétinoblastome trilatéral en milieu africain burkinabé : à propos de trois cas.

The authors describe three cases of trilateral retinoblastoma, a rare syndrome that occurs most often in young children. Two of these children were 3 years old at diagnosis, and the other 4 years old. The retinoblastoma was unilateral in one child and bilateral in the others. All underwent computed tomography (CT) imaging, which made it possible to locate the intraocular tumor lesions, to specify the extent of the tumor and to look for a possible intracranial neoplasm. Unfortunately, the cost of CT is high, which limits its use in our context.