Meningoencephalitis, pancytopenia, pulmonary insufficiency and splenic abscess in a patient with brucellosis.

A complicated case of brucellosis with some rare features is reported. Brucellosis is a multisystemic disease. However, disseminated brucellosis with cerebral, pulmonary, hematopoietic and splenic involvement in an otherwise healthy patient is a rare event. In this article, we report a case of disseminated brucellosis who was initially diagnosed as myelodysplastic syndrome MDS and meningoencephalitis, pulmonary symptoms, and splenic abscess formation occurred thereafter.

A case of brucellar septic arthritis of the knee with a prolonged clinical course.

Brucellosis is a systemic infectious disease with a broad spectrum of clinical manifestations. Arthritis is frequently observed in its course and may be one of the main presenting clinical features of the disease. We report a case of brucellar monoarthritis of the knee with a prolonged clinical course despite efficient antibiotic treatment.

Nasal carriage of methicillin-resistant Staphylococcus aureus among hospital staff and outpatients.

This study sought to determine the rate of nasal methicillin-resistant Staphylococcus aureus (MRSA) carriage among hospital staff and outpatients. Nasal swabs were obtained from 500 outpatients and 500 hospital staff. Hospital staff were 2.3-fold more likely to carry MRSA than were outpatients (6% vs 2.6%, P = .013).

[Comparison of protein profiles and antibiotic sensitivity of methicillin-resistant Staphylococcus aureus strains isolated from nasal cultures of polyclinic patients and hospital personnel]. / Poliklinik hastalari ile hastane personelinin burun kültürlerinden izole edilen metisiline dirençli Staphylococcus aureus suslarinin protein profillerinin ve antibiyotik duyarliliklarinin karsilastirilmasi.

In this study, the antibiotic susceptibilities and whole cell protein patterns of methicillin resistant Staphylococcus aureus (MRSA) strains which were isolated from nasal swabs of outpatients and healthy hospital staff, have been determined by disk diffusion test and sodium dodecyl sulfate polyacrylamide gel electrophoresis method, respectively. A total of 43 MRSA isolates of which 13 out of 500 outpatients and 30 out of 500 hospital personnel, showed the same protein profiles, and the antibiotic susceptibility patterns were found similar. These findings suggested that the strains isolated from the outpatients were originated from hospital environment.

[Prolonged hepatitis A: three case reports]. / Uzamis hepatit A: üç olgu raporu.

In this report, three patients, admitted to Ankara University Faculty of Medicine, Ibni Sina Hospital, Clinical Bacteriology and Infectious Diseases Department, with the diagnosis of acute viral hepatitis A have been discussed because of their clinical and/or biochemical relapses. Following conservative treatment and bedrest, the liver transaminases decrease to nearly normal levels but a second peak was observed later in three of the cases. Other viral, metabolic and autoimmune factors which could lead to the increase of liver transaminases were ruled out. Anti-HAV IgM antibodies became negative in 2 to 4 months later, and liver enzymes returned to normal in 4 to 5 months after onset of their illnesses. As a result, it was concluded that conservative follow-up and therapy would be sufficient since the prognosis of A hepatitis is usually benign even if it relapsed.

A case of anthrax meningitis.

Meningeal anthrax is a very rare complication of the cutaneous, respiratory and gastrointestinal form of anthrax infection. Anthrax bacilli, most commonly enter the body via the skin, and the organism then disseminates to the central nervous system via the hematogenous or lymphatic routes leading to fatal bacterial meningitis, even with intensive antibacterial therapy.

[In vitro sensitivity of methicillin-resistant Staphylococcus aureus to fusidic acid and trimethoprim-sulfamethoxazole]. / Metisiline dirençli Staphylococcus aureus suslarinin fusidik asit ve trimetoprim-sulfametokaszole in-vitro duyarliligi.

In this study, a total of 225 methicillin resistant Staphylococcus aureus strains isolated from various clinical specimens (114 wounds, 27 blood, 16 of each catheter and sputum, 14 throat swabs, 10 tracheal aspirates, 7 of each urine and drain materials, 6 pleural fluids, 5 graft materials, 2 cerebrospinal fluids, 1 ascitis fluid) of hospitalized patients, were tested in-vitro for their susceptibilities to fusidic acid and trimethoprim-sulfamethoxazole (TMP-SMX) by disk diffusion method. Two-hundred-eighteen (96.9%) of isolates were found susceptible to both fusidic acid and TMP-SMX, 4 (1.8%) were resistant to both of the agents (3 isolates from wound, 1 from sputum), 2 (0.9%) (both of them were wound isolates) were resistant only to fusidic acid, and 1 (0.4%) (throat isolate) was resistant only to TMP-SMX.

[Determination of nasal carriage rates of methicillin resistant Staphylococcus aureus in hospital personnel and in the community]. / Hastane personelinde ve toplumda metisiline dirençli Staphylococcus aureus nazal tasiyicilik oranlarinin belirlenmesi.

In this study, methicillin resistant Staphylococcus aureus (MRSA) nasal carriage rates in hospital staff and community were investigated. The study included 500 hospital personnel and 500 outpatients in Ibni Sina Hospital and Cebeci Hospital of Ankara University School of Medicine between January 1999-March 2001. Outpatients were assigned into the control group and hospital staff into the study group. MRSA nasal carriage rates of hospital staff and control group were found to be 6% and 2.6%, respectively, and the difference between these groups were statistically significant (p < 0.001). There was no significant difference in the nasal carriage rates among the different members of the hospital personnel such as physicians, nurses and auxilliary staff (p > 0.05), however the rates were higher especially in the personnel who were mainly working in the surgical wards and operating theaters.