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PLoS One ; 13(2): e0191804, 2018.
Artículo en Inglés | MEDLINE | ID: mdl-29389976

RESUMEN

There are no universally approved re-vaccination guidelines for non-transplant pediatric cancer survivors. We hypothesized that by utilizing a response-based re-vaccination schedule, we could tailor vaccine schedules in off-treatment cancer survivors. Pre-vaccination antibody levels were obtained in 7 patients at an average of 20 days after the end of treatment date. In those without protective antibody levels, we administered vaccines 3 months after completion of treatment. Revaccinating patients 3 months after the end of treatment date resulted in protective antibody levels for most vaccines. We showed, on a preliminary basis, that vaccinating non-transplanted pediatric cancer survivors can be dynamically implemented in children with recovering immune function.


Asunto(s)
Neoplasias/inmunología , Sobrevivientes , Vacunas/administración & dosificación , Formación de Anticuerpos , Niño , Estudios de Factibilidad , Femenino , Humanos , Masculino , Vacunas/inmunología
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