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PURPOSE: The French National Cancer Institute has developed, in partnership with the French National Authority for Health, breast cancer-specific Care Quality, and Safety Indicators (BC QIs). With regard to the most common form of cancer, our aim is to support local and national quality initiatives, to improve BC pathways and outcomes, reduce heterogeneity of practice and regional inequities. In this study, we measure the BC QIs available in the French National medico-administrative cancer database, the French Cancer Cohort, for 2018. MATERIALS AND METHODS: BC QIs are developed according to the RAND method. QIs are based on good clinical practice and care pathway recommendations. QI computation should be automatable without any additional workload for data collection. They will be published annually for all stakeholders, and especially hospitals. RESULTS: Finally, ten feasible and pertinent QIs were selected. In France, BC care was found to be close to compliance with most QIs: proportion of patients undergoing biopsy prior to first treatment (94.5%), proportion of patients undergoing adjuvant radiotherapy after breast-conserving surgery for BC (94.5%), proportion of women undergoing radiotherapy within 12 weeks after surgery and without chemotherapy (86.2%), proportion of DCIS patients undergoing immediate breast reconstruction (54.3%) and proportion of women with NMIBC undergoing breast reintervention (14.4%). However, some are still far from their recommended rate. In particular, some QIs vary considerably from one region, or one patient, to another. CONCLUSION: Each result needs to be analyzed locally to find care quality leverage. This will strengthen transparency actions aimed at the public.
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Neoplasias de la Mama , Neoplasias de la Mama/patología , Femenino , Humanos , Mastectomía Segmentaria , Indicadores de Calidad de la Atención de Salud , Calidad de la Atención de Salud , Radioterapia AdyuvanteRESUMEN
OBJECTIVES: Premedication practices for neonatal tracheal intubations have not yet been described for neonatal transport teams. Our objective is to describe the use of sedation/analgesia (SA) for tracheal intubations and to assess its tolerance in neonates transported by medical transport teams in France. SETTING: This prospective observational study was part of the EPIPPAIN 2 project and collected around-the-clock data on SA practices in neonates intubated by all five paediatric medical transport teams of the Paris region during a 2-month period. Intubations were classified as emergent, semiemergent and non-emergent. Sedation level and conditions of intubation were assessed with the Tonus, Reactivity, Awareness and Conditions of intubation to Help in Endotracheal intubation Assessment (TRACHEA score). The scores range from 0 to 10 representing an increasing ladder from adequate to inadequate sedation, and from excellent to very poor conditions of intubation. PARTICIPANTS: 40 neonates intubated in 28 different centres. RESULTS: The mean (SD) age was 34.9 (3.9) weeks, and 62.5% were intubated in the delivery room. 30/40 (75%) of intubations were performed with the use of SA. In 18/30 (60.0%) intubations performed with SA, the drug regimen was the association of sufentanil and midazolam. Atropine was given in 19/40 intubations. From the 16, 21 and 3 intubations classified as emergent, semiemergent and non-emergent, respectively, 8 (50%), 19 (90.5%) and 3 (100%) were performed with SA premedication. 79.3% of intubations performed with SA had TRACHEA scores of 3 or less. 22/40 (55%) infants had at least one of the following adverse events: muscle rigidity, bradycardia below 100/min, desaturation below 80% and nose or pharynx-larynx bleeding. 7/24 (29.2%) of those who had only one attempt presented at least one of these adverse events compared with 15/16 (93.8%) of those who needed two or more attempts (p<0.001). CONCLUSION: SA premedication is largely feasible for tracheal intubations performed in neonates transported by medical transport teams including intubations judged as emergent or semiemergent. TRIAL REGISTRATION NUMBER: NCT01346813; Results.
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Analgésicos Opioides/uso terapéutico , Intubación Intratraqueal/métodos , Premedicación/estadística & datos numéricos , Atropina/uso terapéutico , Femenino , Humanos , Recién Nacido , Unidades de Cuidado Intensivo Neonatal , Intubación Intratraqueal/efectos adversos , Masculino , Midazolam/uso terapéutico , Dolor/epidemiología , Dolor/etiología , Paris , Estudios Prospectivos , Sufentanilo/uso terapéuticoRESUMEN
OBJECTIVES: To assess premedication practices before tracheal intubation of premature newborns in the delivery room (DR). STUDY DESIGN: From the national population-based prospective EPIPAGE 2 cohort in 2011, we extracted all live born preterms intubated in the DR in level-3 centers, without subsequent circulatory resuscitation. Studied outcomes included the rate and type of premedication, infants' and maternities' characteristics and survival and major neonatal morbidities at discharge from hospital. Univariate and multivariate analysis were performed and a generalized estimating equation was used to identify factors associated with premedication use. RESULTS: Out of 1494 included neonates born in 65 maternities, 76 (5.1%) received a premedication. Midazolam was the most used drug accounting for 49% of the nine drugs regimens observed. Premedicated, as compared to non premedicated neonates, had a higher median [IQR] gestational age (30 [28-31] vs 28 [27-30] weeks, p<10-3), median birth weight (1391 [1037-1767] vs 1074 [840-1440] g, p<10-3) and median 1-minute Apgar score (8 [6-9] vs 6 [3-8], p<10-3). Using univariate analyses, premedication was significantly less frequent after maternal general anesthesia and during nighttime and survival without major morbidity was significantly higher among premedicated neonates (56/73 (81.4%) vs 870/1341 (69.3%), p = 0.028). Only 10 centers used premedication at least once and had characteristics comparable to the 55 other centers. In these 10 centers, premedication rates varied from 2% to 75%, and multivariate analysis identified gestational age and 1-minute Apgar score as independent factors associated with premedication use. CONCLUSION: Premedication rate before tracheal intubation was only 5.1% in the DR of level-3 maternities for premature neonates below 34 weeks of gestation in France in 2011 and seemed to be mainly associated with centers' local policies.
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Enfermedades del Prematuro/prevención & control , Midazolam/uso terapéutico , Premedicación/métodos , Peso al Nacer , Estudios de Cohortes , Salas de Parto , Femenino , Francia/epidemiología , Edad Gestacional , Humanos , Recién Nacido , Enfermedades del Prematuro/epidemiología , Intubación Intratraqueal , Masculino , Morbilidad , Embarazo , Estudios Retrospectivos , Factores de RiesgoRESUMEN
AIM: Continuous pain occurs routinely, even after invasive procedures, or inflammation and surgery, but clinical practices associated with assessments of continuous pain remain unknown. METHODS: A prospective cohort study in 243 neonatal intensive care units (NICUs) from 18 European countries recorded the frequency of pain assessments, use of mechanical ventilation, sedation, analgesia or neuromuscular blockade for each neonate for up to 28 days after NICU admission. RESULTS: Only 2113 of 6648 (31.8%) of neonates received assessments of continuous pain, occurring variably among tracheal ventilation (TrV, 46.0%), noninvasive ventilation (NiV, 35.0%) and no ventilation (NoV, 20.1%) groups (p < 0.001). Daily assessments for continuous pain occurred in only 10.4% of all neonates (TrV: 14.0%, NiV: 10.7%, NoV: 7.6%; p < 0.001). More frequent assessments of continuous pain occurred in NICUs with pain guidelines, nursing champions and surgical admissions (all p < 0.01), and for newborns <32 weeks gestational age, those requiring ventilation, or opioids, sedatives-hypnotics, general anaesthetics (O-SH-GA) (all p < 0.001), or surgery (p = 0.028). Use of O-SH-GA drugs increased the odds for pain assessment in the TrV (OR:1.60, p < 0.001) and NiV groups (OR:1.40, p < 0.001). CONCLUSION: Assessments of continuous pain occurred in less than one-third of NICU admissions and daily in only 10% of neonates. NICU clinical practices should consider including routine assessments of continuous pain in newborns.
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Dolor Crónico/diagnóstico , Unidades de Cuidado Intensivo Neonatal/estadística & datos numéricos , Dimensión del Dolor/estadística & datos numéricos , Europa (Continente) , Femenino , Humanos , Recién Nacido , Recien Nacido Prematuro , Masculino , Estudios Prospectivos , Respiración ArtificialRESUMEN
BACKGROUND: We aimed to examine current bedside analgesia/sedation (A/S) and pain assessment (PA) practices in Italian neonatal intensive care units (NICUs) in relation to the findings of an epidemiological European study and recently-introduced national guidelines. METHODS: We analyzed the Italian data from the EUROPAIN (EUROpean-Pain-Audit-In-Neonates) prospective observational study on A/S practices that involved 6680 newborns admitted to tertiary-level NICUs in 18 European countries. Demographics, type of assisted ventilation, type and mode of A/S administration and PA were analyzed. Multivariate linear regression models were used to identify factors predicting A/S and PA practices. RESULTS: From October 1st, 2012 to June 30th, 2013, thirty Italian NICUs gathered data on 422 newborn: 131 on invasive ventilation (IV); 150 on noninvasive ventilation (NIV); and 141 on spontaneous ventilation (SV). A/S was documented for 35.3% of all infants admitted (86.3% IV; 17.3% NIV; 7.1% SV [p = 0.0001]), and varied considerably between NICUs (as reported in other European countries). Strong analgesics were used in 32.5% of cases, sedatives in 10.2%, mild analgesics in 3.8%. Fentanyl was used in 78.6% of cases, morphine in 8.4%, neuromuscular blockers in 5.3%, midazolam in 22.1%. The performance of PA was documented in 67.5% of all newborn (85.5% IV; 67.3% NIV; 51.1% SV [p = 0.001]). Illness severity, type of ventilation, bedside PA, and number of NICU beds were all factors associated with A/S use on multivariate analysis, while gestational age ≤ 32 weeks, and type of ventilation and presence of a pain team were associated with PA. CONCLUSIONS: We documented a generally widespread, but still highly variable use of A/S and PA at Italian NICUs, despite the diffusion of national guidelines. There is an urgent need to improve routine PA to enable customized pain and stress control (and prevention) in all infants. TRIAL REGISTRATION: Clinical Trials.gov # NCT01694745 .
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Analgesia/métodos , Analgésicos/administración & dosificación , Sedación Consciente/métodos , Hipnóticos y Sedantes/administración & dosificación , Unidades de Cuidado Intensivo Neonatal , Dimensión del Dolor/métodos , Dolor/epidemiología , Europa (Continente)/epidemiología , Femenino , Estudios de Seguimiento , Edad Gestacional , Humanos , Incidencia , Recién Nacido , Masculino , Manejo del Dolor/métodos , Estudios Prospectivos , Respiración Artificial/métodos , Encuestas y CuestionariosRESUMEN
INTRODUCCIÓN: Las escalas clínicas son hoy en día el mejor método para evaluar el dolor en el neonato, dada la imposibilidad de autorreporte en este grupo de edad. Se diseñó un estudio con el objetivo de determinar las prácticas actuales en relación con la valoración clínica del dolor en España y los factores asociados al uso de escalas clínicas.MÉTODOS: El estudio es de tipo observacional, longitudinal y prospectivo. Participaron 30 unidades y se reclutó a 468 neonatos. RESULTADOS: Solo 13 unidades (43,3%) disponían de protocolos de valoración del dolor. Se evaluó el dolor con una escala en 78 neonatos (16,7%, IC del 95%, 13,1-20,1) y el número medio de valoraciones del dolor por paciente y día de estancia fue de 2,3 ± 4,8, con una mediana de 0,75. Del total de 7.189 días-paciente estudiados, 654 (9,1%) conllevaron al menos una valoración del dolor. Veinte unidades (66,7%) no realizaron evaluación del dolor con una escala clínica en ningún paciente. Entre las que sí lo hicieron, se observó una gran variabilidad en el porcentaje de pacientes en los que se evaluó el dolor y en las escalas utilizadas. La escala CRIES (C-Crying; R-Requires increased oxygen administration; I-Increased vital signs; E-Expression; SSleeplessness) fue la que se usó en más unidades. En el análisis multivariante solo la ventilación mecánica invasiva se asoció a recibir valoración del dolor con una escala (OR 1,46, p = 0,042). DISCUSIÓN: La mayoría de los neonatos ingresados en cuidados intensivos en España no recibe una valoración del dolor. Muchas unidades todavía no utilizan rutinariamente las escalas clínicas y entre las que las utilizan existe una gran variabilidad. Estos resultados pueden servir de base para la elaboración de guías nacionales al respecto del dolor en el neonato
INTRODUCTION: Clinical scales are currently the best method to assess pain in the neonate, given the impossibility of self-report in this age group. A study is designed with the aim of determining the current practices as regards the clinical assessment of pain in Spanish Neonatal Units and the factors associated with the use of clinical scales. METHODS: A prospective longitudinal observational study was conducted. A total of 30 Units participated and 468 neonates were included. RESULTS: Only 13 Units (43.3%) had pain assessment protocols. Pain was evaluated with a scale in 78 neonates (16.7%, 95% CI; 13.1-20.1) and the mean number of pain assessments per patient and per day was 2.3 (Standard Deviation; 4.8), with a median of 0.75. Of the total number of 7,189 patient-days studied, there was at least one pain assessment in 654 (9.1%). No pain assessment was performed with a clinical scale on any patient in 20 (66.7%) Units. Among those that did, a wide variation was observed in the percentage of patients in whom pain was assessed, as well as in the scales used. The CRIES (C-Crying; R-Requires increased oxygen administration; I-Increased vital signs; E-Expression; S-Sleeplessness) scale was that used in most Units. In the multivariate analysis, only invasive mechanical ventilation was associated with receiving a pain assessment with a scale (OR 1.46, P=.042). DISCUSSION: The majority of neonates admitted into Intensive Care in Spain do not receive a pain assessment. Many units still do not routinely use clinical scales, and there is a wide variation between those that do use them. These results could serve as a basis for preparing national guidelines as regards pain in the neonate
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Humanos , Masculino , Femenino , Recién Nacido , Unidades de Cuidado Intensivo Neonatal , Dimensión del Dolor , Manejo del Dolor , Analgésicos/uso terapéutico , Estudios Prospectivos , Estudios Longitudinales , EspañaRESUMEN
BACKGROUND: Heelstick is the most frequently performed skin-breaking procedure in the neonatal intensive care units (NICUs). There are no large multicenter studies describing the frequency and analgesic approaches used for heelsticks performed in NICUs. OBJECTIVES: To describe the frequency of heelsticks and their analgesic management in newborns in the NICU. To determine the factors associated with the lack of specific preprocedural analgesia for this procedure. DESIGN: EPIPPAIN 2 (Epidemiology of Procedural PAin In Neonates) is a descriptive prospective epidemiologic study. SETTING: All 16 NICUs in the Paris region in France. PARTICIPANTS: All newborns in the NICU with a maximum corrected age of 44 weeks +6 days of gestation on admission who had at least one heelstick during the study period were eligible for the study. The study included 562 newborns. METHODS: Data on all heelsticks and their corresponding analgesic therapies were prospectively collected. The inclusion period lasted six weeks, from June 2, 2011 to July 12, 2011. Newborns were followed from their admission to the 14th day of their NICU stay or discharge, whichever occurred first. RESULTS: The mean (SD) gestational age was 33.3 (4.4) weeks and duration of participation was 7.5 (4.4) days. The mean (SD; range) of heelsticks per neonate was 16.0 (14.4; 1-86) during the study period. Of the 8995 heelsticks studied, 2379 (26.4%) were performed with continuous analgesia, 5236 (58.2%) with specific preprocedural analgesia. Overall, 6764 (75.2%) heelsticks were performed with analgesia (continuous and/or specific). In a multivariate model, the increased lack of preprocedural analgesia was associated with female sex, term birth, high illness severity, tracheal or noninvasive ventilation, parental absence and use of continuous sedation/analgesia. CONCLUSIONS: Heelstick was very frequently performed in NICUs. Although, most heelsticks were performed with analgesia, this was not systematic. The high frequency of this procedure and the known adverse effects of repetitive pain in neonates should encourage the search of safe and effective strategies to reduce their number.
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Unidades de Cuidado Intensivo Neonatal , Manejo del Dolor/métodos , Talón , Humanos , Recién Nacido , Flebotomía/métodos , Estudios ProspectivosRESUMEN
Theme: Nursing education, management and leadership.
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BACKGROUND: Newborns in intensive care units (ICUs) undergo numerous painful procedures including venipunctures. Skin-breaking procedures have been associated with adverse neurodevelopment long-term effects in very preterm neonates. The venipuncture frequency and its real bedside pain management treatment are not well known in this setting. OBJECTIVES: To describe venipuncture frequency, its pain intensity, and the analgesic approach in ICU newborns; to determine the factors associated with the lack of preprocedural analgesia and with a high pain score during venipuncture. DESIGN: Further analysis of EPIPPAIN 2 (Epidemiology of Procedural Pain In Neonates), which is a descriptive prospective epidemiologic study. SETTING: All 16 neonatal and pediatric ICUs in the Paris region in France. PARTICIPANTS: All newborns in the ICU with a maximum corrected age under 45 weeks of gestation on admission who had at least one venipuncture during the study period. METHODS: Data on all venipunctures, their pain score assessed with the DAN scale and their corresponding analgesic therapies were prospectively collected. The inclusion period lasted six weeks, from June 2, 2011, to July 12, 2011. Newborns were followed from their admission to the 14th day of their ICU stay or discharge, whichever occurred first. RESULTS: 495 newborns who underwent venipunctures were included. The mean (SD) gestational age was 33.0 (4.4) weeks and duration of participation was 8.0 (4.5) days. A total of 257 (51.9%) neonates were very preterm (<33 weeks). The mean (SD; range) number of venipunctures per neonate during the study period was 3.8 (2.8; 1-19) for all neonates and 4.1 (2.9; 1-17) for neonates <33 weeks. Of the 1887 venipunctures, 1164 (61.7%) were performed successfully in one attempt, 437 (23.2%) with continuous analgesia, 1434 (76.0%) with specific preprocedural analgesia. In multivariate models, lack of preprocedural analgesia was associated with higher disease-severity score, intrauterine growth retardation, invasive or noninvasive ventilation, venipuncture performed on the first day of hospitalization or at nighttime, and the use of continuous sedation/analgesia. High pain scores were significantly associated with absence of parents during procedures, surgery during the study period, and higher number of attempts. CONCLUSIONS: Venipuncture is very frequent in preterm and term neonates in the ICUs. 76% were performed with preprocedural analgesia. Strategies to reduce the number of attempts and to promote parental presence seem necessary.
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Dolor/etiología , Flebotomía/efectos adversos , Humanos , Recién Nacido , Paris , Estudios ProspectivosRESUMEN
INTRODUCTION: Clinical scales are currently the best method to assess pain in the neonate, given the impossibility of self-report in this age group. A study is designed with the aim of determining the current practices as regards the clinical assessment of pain in Spanish Neonatal Units and the factors associated with the use of clinical scales. METHODS: A prospective longitudinal observational study was conducted. A total of 30 Units participated and 468 neonates were included. RESULTS: Only 13 Units (43.3%) had pain assessment protocols. Pain was evaluated with a scale in 78 neonates (16.7%, 95% CI; 13.1-20.1) and the mean number of pain assessments per patient and per day was 2.3 (Standard Deviation; 4.8), with a median of 0.75. Of the total number of 7,189 patient-days studied, there was at least one pain assessment in 654 (9.1%). No pain assessment was performed with a clinical scale on any patient in 20 (66.7%) Units. Among those that did, a wide variation was observed in the percentage of patients in whom pain was assessed, as well as in the scales used. The CRIES (C-Crying; R-Requires increased oxygen administration; I-Increased vital signs; E-Expression; S-Sleeplessness) scale was that used in most Units. In the multivariate analysis, only invasive mechanical ventilation was associated with receiving a pain assessment with a scale (OR 1.46, P=.042). DISCUSSION: The majority of neonates admitted into Intensive Care in Spain do not receive a pain assessment. Many units still do not routinely use clinical scales, and there is a wide variation between those that do use them. These results could serve as a basis for preparing national guidelines as regards pain in the neonate.
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Unidades de Cuidado Intensivo Neonatal , Manejo del Dolor , Dimensión del Dolor , Analgésicos/uso terapéutico , Femenino , Humanos , Recién Nacido , Estudios Longitudinales , Masculino , Estudios Prospectivos , EspañaRESUMEN
BACKGROUND: Neonates who are in pain or are stressed during care in the intensive care unit (ICU) are often given sedation or analgesia. We investigated the current use of sedation or analgesia in neonatal ICUs (NICUs) in European countries. METHODS: EUROPAIN (EUROpean Pain Audit In Neonates) was a prospective cohort study of the management of sedation and analgesia in patients in NICUs. All neonates admitted to NICUs during 1 month were included in this study. Data on demographics, methods of respiration, use of continuous or intermittent sedation, analgesia, or neuromuscular blockers, pain assessments, and drug withdrawal syndromes were gathered during the first 28 days of admission to NICUs. Multivariable linear regression models and propensity scores were used to assess the association between duration of tracheal ventilation (TV) and exposure to opioids, sedatives-hypnotics, or general anaesthetics in neonates (O-SH-GA). This study is registered with ClinicalTrials.gov, number NCT01694745. FINDINGS: From Oct 1, 2012, to June 30, 2013, 6680 neonates were enrolled in 243 NICUs in 18 European countries. Mean gestational age of these neonates was 35.0 weeks (SD 4.6) and birthweight was 2384 g (1007). 2142 (32%) neonates were given TV, 1496 (22%) non-invasive ventilation (NIV), and 3042 (46%) were kept on spontaneous ventilation (SV). 1746 (82%), 266 (18%), and 282 (9%) neonates in the TV, NIV, and SV groups, respectively, were given sedation or analgesia as a continuous infusion, intermittent doses, or both (p<0.0001). In the participating NICUs, the median use of sedation or analgesia was 89.3% (70.0-100) for neonates in the TV group. Opioids were given to 1764 (26%) of 6680 neonates and to 1589 (74%) of 2142 neonates in the TV group. Midazolam was given to 576 (9%) of 6680 neonates and 536 (25%) neonates of 2142 neonates in the TV group. 542 (25%) neonates in the TV group were given neuromuscular blockers, which were administered as continuous infusions to 146 (7%) of these neonates. Pain assessments were recorded in 1250 (58%) of 2138, 672 (45%) of 1493, and 916 (30%) of 3017 neonates in the TV, NIV, and SV groups, respectively (p<0.0001). In the univariate analysis, neonates given O-SH-GA in the TV group needed a longer duration of TV than did those who were not given O-SH-GA (mean 136.2 h [SD 173.1] vs 39.8 h [94.7] h; p<0.0001). Multivariable and propensity score analyses confirmed this association (p<0.0001). INTERPRETATION: Wide variations in sedation and analgesia practices occur between NICUs and countries. Widespread use of O-SH-GA in intubated neonates might prolong their need for mechanical ventilation, but further research is needed to investigate the therapeutic and adverse effects of O-SH-GA in neonates, and to develop new and safe approaches for sedation and analgesia. FUNDING: European Community's Seventh Framework Programme.
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Analgésicos/uso terapéutico , Sedación Consciente/estadística & datos numéricos , Hipnóticos y Sedantes/uso terapéutico , Unidades de Cuidado Intensivo Neonatal/estadística & datos numéricos , Analgésicos Opioides/uso terapéutico , Peso al Nacer , Sedación Consciente/métodos , Europa (Continente) , Femenino , Edad Gestacional , Humanos , Recién Nacido , Masculino , Midazolam/uso terapéutico , Puntaje de Propensión , Estudios Prospectivos , Respiración Artificial/métodos , Respiración Artificial/estadística & datos numéricosRESUMEN
Breastfeeding contributes to the health of the child and the mother. Given the lack of studies done in France, it is relevant to examine, besides the sociodemographic factors, the psychosocial and the relational factors. The objectives of the study are: to describe the proportion of mothers who breastfeed up to six months, to identify the sociodemographic, psychosocial and relational factors. This is a prospective, observational, single-center cohort study. The instruments used are the socio-demographic and clinical data questionnaire, the Maternel Sensitivity Scale, the Social Behavioral Inventory and the Situational Anxiety Inventory. Of the 247 mothers who participed in the study, 134 responded at six months and 55 mothers reported breastfeeding at six months. Multivariate analysis revealed the significant factors associated with the continuation of breastfeeding up to six months: the determination of mothers to breastfeed (OR (95% CI): 3.99 (1.04 to 15.31)), high maternal sensitivity at 48h (OR (95% CI): 0.16 (0.03 to 0.84)) and the presence of maternal anxiety at 48 h (OR (95% CI): 1.18 (1.06 to 1.32)). The conjunction of the interactionist approach and of maternal sensitivity is a promising avenue for the support of breastfeeding. Psychosocial and relational factors are fields that need to be explored. Knowledge of these factors can strengthen the strategies to inform and support breastfeeding mothers.
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Lactancia Materna/estadística & datos numéricos , Madres , Adulto , Ansiedad/psicología , Femenino , Maternidades , Humanos , Lactante , Recién Nacido , Paris , Estudios Prospectivos , Encuestas y CuestionariosRESUMEN
AIM: The most common manifestation of sickle cell disease (SCD) is painful vaso-occlusive episodes (PVOE), and inappropriate treatment leads to unnecessary suffering and potentially fatal complications. This study describes how French paediatric emergency departments (EDs) manage PVOE and their knowledge, and implementation of the French National Authority for Health recommendations on the management of sickle cell patients. METHODS: A questionnaire on managing PVOE was sent to all the 111 French paediatric EDs. RESULTS: We received responses from 81 (72.9%) of the EDs. Of those who responded to each individual question, 85% said that they had read the national recommendations, 71.6% said they used nalbuphine for moderate PVOE, and 85% used intravenous morphine for severe PVOE. The majority (91.7%) of EDs thought that intravenous morphine provided relief for severe PVOE, but only 30.9% thought that intravenous nalbuphine did. A 50:50 nitrous oxide/oxygen mix was used by 71.3% of departments to relieve procedural pain and by 48% to enhance analgesia when morphine was insufficient for severe pain. CONCLUSIONS: Most French EDs follow the national recommendations for PVOE. Nalbuphine was the most commonly used opioid for moderate PVOE and morphine for severe PVOE. A nitrous oxide/oxygen mixture was widely used for PVOE.
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Analgésicos/uso terapéutico , Anemia de Células Falciformes/complicaciones , Servicio de Urgencia en Hospital , Dolor/tratamiento farmacológico , Dolor/etiología , Adolescente , Anemia de Células Falciformes/terapia , Niño , Francia , Adhesión a Directriz , Humanos , Morfina/uso terapéutico , Nalbufina/uso terapéutico , Óxido Nitroso/uso terapéutico , Dolor/diagnóstico , Pautas de la Práctica en Medicina , Encuestas y CuestionariosRESUMEN
The assessment of pain in children in the paediatric emergency department is essential for high quality care. Recognizing pain is not enough: only the use of validated assessments tools enables staff to include pain on part of daily care. The objective analysis of care practices helps to improve the quality of care in children.