RESUMEN
El cáncer de laringe es la segunda neoplasia maligna de cabeza y cuello en adultos. Hemos decidido la búsqueda de un método diagnóstico eficaz y eficiente de las tumoraciones laríngeas sospechosas de malignidad. Se realiza la punción aspiración con aguja fina transcartilaginosa laríngea (PAAF TCL) en las lesiones laríngeas de estadios TNM altos (III y IV) como método diagnóstico alternativo a la tradicional biopsia por microcirugía laríngea. Se logra así la optimización de recursos institucionales y el beneficio de los pacientes en función del tratamiento de los mismos.
Laryngeal cancer is the second leading cause ofhead and neck malignant neoplasms in adults. Wedecided to search for effective diagnostic method oflaryngeal tumors suspicious of malignancy. Transcartilaginous Fine Needle Aspiration Biopsy (TF-NAB) is performed in laryngeal lesions of high levelTNM stage (III and IV) as an alternative to traditionalbiopsy by laryngeal microsurgery. It achievesthe optimization of institutional resources and thebenefit of patients according to their treatment.
O câncer de laringe é segunda neoplasia maligna de cabeça e pescoço em adultos. Decidimos buscar um método diagnóstico eficaz e eficiente das tumorações laríngeas com suspeitas de malignidade.Realiza-se a Punção Aspiração com Agulha Fina Transcartilaginosa Laríngea (PAAF TCL) nas lesões laríngeas de estádios TNM altos (III e IV) como método diagnóstico alternativo à tradicional biopsia por microcirurgia laríngea. Obtém-se assim a otimização de recursos institucionais e o benefício dos pacientes em função do seu tratamento.
Asunto(s)
Humanos , Biopsia con Aguja Fina/instrumentación , Biopsia con Aguja Fina/métodos , Neoplasias Laríngeas/diagnóstico , Análisis Costo-Eficiencia , Análisis Costo-BeneficioRESUMEN
La psoriasis es una enfermedad cutánea inflamatoria crónica, recidivante, que afecta al 2% de la población. Se clasifica de acuerdo a su apariencia morfológica. Existen formas raras excesivamente hiperqueratósicas, entre ellas la variante rupioides, de la cual se han reportado pocos casos en la literatura. Presentamos un caso clínico de psoriasis rupiodes diseminada con buena respuesta al tratamiento sistémico con acitretin
Psoriasis is a relapsing chronic inflammatory skin disease affecting about 2% of population. It is classified according morphological appearance. There are exceedingly rare hyperkeratotic forms, including rupioid variant, which few cases have been reported in the literature. A case of widespread rupioid psoriasis with good response to systemic treatment with acitretin is presented.
Asunto(s)
Humanos , Femenino , Adulto , Acitretina , Psoriasis/clasificación , Psoriasis/etiología , Bolivia , Enfermedades de la PielRESUMEN
The Dubin-Johnson syndrome is a hereditary deficiency in the excretion ofconjugated bilirrubin by hepatocytes characterized by chronic hyperbilirubinemia, alteration in coproporphyrin metabolism, and intracellular deposition of a dark melanin-like pigment giving the liver a typical black cast. We report a 28-year-old male patient who presented conjunctival jaundice and conjugated-hyperbilirubinemia without no other alteration in hepatic biochemistry. The diagnosis of this syndrome was perfomed by using the low-risk methods of laparoscopy-facilitated hepatic biopsy and oral cholecystography In contrast, we avoided the classical Bromsulphalein test because of potential severe side effects. We stress here the current importance of these tests for confirming the diagnosis. By using this methodology, we were not able to quantify the isomeric profile of the urinary coproporphyrins nor 99mTc-HIDA cholescintigraphy. In conclusion, we confirm the utility of hepatic biopsy with the aid of laparoscopy and oral cholecystography for the diagnosis of the Dubin-Johnson syndrome on the basis of their effectiveness and relative lack of complications.
