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1.
Sci Total Environ ; 807(Pt 3): 151053, 2022 Feb 10.
Artículo en Inglés | MEDLINE | ID: mdl-34673065

RESUMEN

The State of Nevada, USA Administrative Code requires a 12-log enteric virus reduction/inactivation, 10-log Giardia cyst reduction, and 10-log Cryptosporidium oocyst reduction for Category A+ reclaimed water suitable for indirect potable reuse (IPR) based on raw wastewater to potable reuse water. Accurately demonstrating log10 reduction values (LRVs) through secondary biological treatment prior to an advanced water treatment train enables redundancy and resiliency for IPR projects while maintaining a high level of public confidence. LRVs for Cryptosporidium and Giardia resulting from secondary biological treatment are not fully established due to a wide range of performance variabilities resulting from different types of secondary biological treatment processes employed in water reclamation. A one-year investigation of two full-scale northern Nevada (e.g. ≤4 mgd; 1.5 × 107 L/day) water reclamation facilities (WRFs) was conducted to monitor Cryptosporidium oocysts and Giardia cysts in untreated wastewater and secondary effluent. This study aimed at establishing secondary treatment LRVs, monitor WRF performance and attempted to correlate performance to protozoan reduction. California's IPR regulations, in which Nevada IPR regulations were modeled after, were based on a maximum concentration of 5-logs (cysts/L) of Giardia and 4-logs (oocysts/L) of Cryptosporidium. The recovery-corrected Giardia and Cryptosporidium concentrations measured in untreated influent (20 samples each at each WRF) were below 5-log cysts/L at the 99th percentile (maximum 4.4-log cysts/L) and 4-log oocysts/L (maximum 2.7 log oocysts/L), respectively. Both secondary treatment WRFs produced secondary effluent that is consistently better than federal and the State of Nevada requirements and perform within an operating envelop for other secondary facilities. Given the results, it appears that a minimum conservative estimate for LRVs for well-operated secondary activated sludge treatment plants (at the 5th percentile) of 0.5 LRV credit for Cryptosporidium and 2.0 LRV for Giardia is warranted. These minimum LRVs are consistent with a conservative review of the available literature.


Asunto(s)
Cryptosporidium , Giardia/aislamiento & purificación , Purificación del Agua , Cryptosporidium/aislamiento & purificación , Nevada , Oocistos/aislamiento & purificación , Aguas Residuales
2.
Regul Toxicol Pharmacol ; 60(1): 1-19, 2011 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-20056125

RESUMEN

The detection of drugs in drinking water sources has raised questions related to safety. In the absence of regulatory or other official guidance, water utilities are faced with a problem of which drugs should be monitored and the detection limits that should be required. The US FDA summarizes data required for drug approval and post marketing adverse reaction reporting. The use of these data as a means of arriving at concentrations in water where adverse health effects are minimal or non-existent was explored. The minimum therapeutic dose was assumed an appropriate point of departure. Appropriate uncertainty factors could be applied depending upon the qualitative and quantitative nature of the data that are available. Assumptions inherent in US FDA's approval of drugs for use in subsets of the population relative to the broader concerns that arise for exposures of the entire population had to be considered. Additional questions are; whether the drug under consideration is carcinogenic, carries pregnancy and lactation warnings, approval for limited vs. chronic use, exposures to multiple compounds that could act in additive or synergistic ways, and the seriousness of toxicities that are observed. Aside from these considerations, a combined uncertainty factor of 1000 appeared adequate.


Asunto(s)
Efectos Colaterales y Reacciones Adversas Relacionados con Medicamentos , Reciclaje/métodos , Eliminación de Residuos Líquidos/métodos , Contaminantes Químicos del Agua/efectos adversos , Purificación del Agua/métodos , Abastecimiento de Agua , Animales , Animales de Laboratorio , Relación Dosis-Respuesta a Droga , Monitoreo del Ambiente , Humanos , Preparaciones Farmacéuticas/análisis , Preparaciones Farmacéuticas/normas , Reciclaje/normas , Medición de Riesgo , Eliminación de Residuos Líquidos/normas , Contaminantes Químicos del Agua/análisis , Contaminantes Químicos del Agua/normas , Purificación del Agua/normas , Abastecimiento de Agua/análisis , Abastecimiento de Agua/normas
3.
Environ Sci Technol ; 37(9): 1882-91, 2003 May 01.
Artículo en Inglés | MEDLINE | ID: mdl-12775061

RESUMEN

The City of Stockton, CA operates a wastewater treatment facility that discharges tertiary treated effluent during the summer and secondary treated effluent during the winter to the San Joaquin River. Investigations were carried out between 1996 and 2002 to provide insight regarding the potential public health benefit that may be provided by year-round tertiary treatment. A hydraulic model of the San Joaquin River and a dynamic disease transmission model integrated a wide array of disparate data to estimate the level of viral gastroenteritis in the population under the two treatment scenarios. The results of the investigation suggest that risk of viral gastroenteritis attributable to the treatment facility under the existing treatment scheme is several orders of magnitude below the 8-14 illnesses per 1000 recreation events considered tolerable by U.S. EPA, and winter tertiary treatment would further reduce the existing risk by approximately 15-50%. The methodologies employed herein are applicable to other watersheds where additional water treatment is being considered to address public health concerns from recreation in receiving waters.


Asunto(s)
Modelos Teóricos , Salud Pública , Recreación , Eliminación de Residuos Líquidos/métodos , Purificación del Agua , Abastecimiento de Agua , Gastroenteritis/etiología , Gastroenteritis/virología , Humanos , Medición de Riesgo , Estaciones del Año
4.
Mendoza; INCYTH; 1995. 34 p.
Monografía en Español | BINACIS | ID: biblio-1220911
5.
Mendoza; INCYTH; 1995. 19 p.
Monografía en Español | BINACIS | ID: biblio-1220912
6.
Mendoza; INCYTH; 1995. 19 p.
Monografía en Inglés | BINACIS | ID: bin-138229
7.
Mendoza; INCYTH; 1995. 34 p.
Monografía en Inglés | BINACIS | ID: bin-138228
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